Cardiovascular risks of chemo-immunotherapy for lung cancer: A population-based cohort study

Review Cardiac & Cardiovascular Systems

Cardiovascular Outcomes and Hospitalizations in Asian Patients Receiving Immune Checkpoint Inhibitors: A Population-based Study

Jeffrey Shi Kai Chan et al.

Summary: This retrospective cohort study examined the associations between immune checkpoint inhibitors (ICI) and adverse cardiovascular events in Asian users. The results showed that MACE and cardiovascular hospitalization rates were highest during the first year after initiating ICI. Compared to non-Asian users, Asian users had a lower incidence of MACE and a smaller proportion of cardiovascular-related hospitalizations.

CURRENT PROBLEMS IN CARDIOLOGY (2023)

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Review Cardiac & Cardiovascular Systems

Inequity in Cardio-Oncology: Identifying Disparities in Cardiotoxicity and Links to Cardiac and Cancer Outcomes

Rachel E. Ohman et al.

Summary: Minority and underresourced communities face higher rates of fatal cancer and cardiovascular disease. Disparities in treatment-associated cardiotoxicity show that black breast cancer survivors have elevated risk, while female patients treated with certain drugs have higher risks compared with male patients. Large-scale studies are needed to better understand racial, ethnic, socioeconomic, and gender disparities in cardio-oncology.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2021)

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Review Immunology

A Network Comparison on Safety Profiling of Immune Checkpoint Inhibitors in Advanced Lung Cancer

Yi-Dan Yan et al.

Summary: This study compared the risk of adverse events across different immune checkpoint inhibitor (ICI) regimens in patients with advanced lung cancer. The findings suggested that treatments containing chemotherapy increased the risk of treatment-related adverse events compared to ICI-based regimens without chemotherapy. Among various ICI-based treatments, ICI monotherapy + chemotherapy was considered a better choice based on the overall immune-related safety profiles.

FRONTIERS IN IMMUNOLOGY (2021)

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Review Oncology