4.4 Article

ALA-PDT regulates macrophage M1 polarization via ERK/MAPK-NLRP3 pathway to promote the early inflammatory response

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro

Lei Li et al.

Summary: This study demonstrates that ALA-PDT can promote wound healing by regulating the formation of granulation tissue, inflammatory process, and M1/M2 macrophages differentiation. In vitro, ALA-PDT can modulate the ratio of M2 polarization to M1 polarization via the NF-KB signaling pathway.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2022)

Article Biochemistry & Molecular Biology

The role of Cryptococcus neoformans histone deacetylase genes in the response to antifungal drugs, epigenetic modulators and to photodynamic therapy mediated by an aluminium phthalocyanine chloride nanoemulsion in vitro

Kunal Ranjan et al.

Summary: The study reveals that genetic variations in histone deacetylase genes of Cryptococcus affect the sensitivity of the pathogen to drugs, and a synergistic effect can be observed when antifungal drugs are combined with histone deacetylase inhibitors. This is the first study to highlight the combined effects of antifungal drugs, histone deacetylase or DNA methyltransferase inhibitors, and photodynamic therapy in vitro for Cryptococcus.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2021)

Review Oncology

Chinese guidelines on the clinical application of 5-aminolevulinic acid-based photodynamic therapy in dermatology (2021 edition)

Lei Shi et al.

Summary: The expert group revised and updated the first edition of the expert consensus statement on Clinical application of 5-aminolevulinic acid-based photodynamic therapy, providing Chinese dermatologists with updated treatment references.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2021)

Review Pharmacology & Pharmacy

Photodynamic Therapy Review: Principles, Photosensitizers, Applications, and Future Directions

Jose H. Correia et al.

Summary: Photodynamic therapy (PDT) is a minimally invasive therapeutic modality that selectively targets tumor cells by using photosensitizers and specific light wavelengths. New research on enhanced tumor selectivity of photosensitizers and improved effectiveness of PDT is being conducted, along with exploring new applications of PDT.

PHARMACEUTICS (2021)

Review Oncology

Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer

Chunxiao Li et al.

Summary: Macrophages play a crucial role in the tumor microenvironment, where they can be polarized into tumor-associated macrophages (TAMs). The abundance of TAMs in tumors is closely linked with poor prognosis, leading to investigations into therapeutic strategies targeting TAMs. These strategies include inhibiting macrophage recruitment to tumors, repolarizing TAMs towards an anti-tumor phenotype, and inducing macrophage-mediated destruction of cancer cells. As tumor immunotherapy gains more importance, new anti-tumor strategies focusing on TAMs are being discussed.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)

Article Biochemistry & Molecular Biology

Photodynamic therapy mediated by aluminium-phthalocyanine nanoemulsion eliminates primary tumors and pulmonary metastases in a murine 4T1 breast adenocarcinoma model

Mosar Correa Rodrigues et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Focus on the Role of NLRP3 Inflammasome in Diseases

Roberta Fusco et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Biochemistry & Molecular Biology

The NLRP3 inflammasome: Mechanism of action, role in disease and therapies

Li Wang et al.

MOLECULAR ASPECTS OF MEDICINE (2020)

Review Biochemistry & Molecular Biology

Daylight Photodynamic Therapy: An Update

Chaw-Ning Lee et al.

MOLECULES (2020)

Article Oncology

Immunogenic cell death induced by a new photodynamic therapy based on photosens and photodithazine

Victoria D. Turubanova et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)

Article Dermatology

Activation of NLRP3 signalling accelerates skin wound healing

Hiroyasu Ito et al.

EXPERIMENTAL DERMATOLOGY (2018)

Article Biochemistry & Molecular Biology

Photodynamic activity of Temoporfin nanoparticles induces a shift to the M1-like phenotype in M2-polarized macrophages

Zhenxin Zhu et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2018)

Review Medicine, General & Internal

Wound healing

Peng-Hui Wang et al.

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION (2018)

Review Oncology

Contribution of photodynamic therapy in wound healing: A systematic review

Vanessa Nesi-Reis et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2018)

Article Multidisciplinary Sciences

Inhibition of the NLRP3-inflammasome as a potential approach for neuroprotection after stroke

Saifudeen Ismael et al.

SCIENTIFIC REPORTS (2018)

Review Biochemistry & Molecular Biology

New photosensitizers for photodynamic therapy

Heidi Abrahamse et al.

BIOCHEMICAL JOURNAL (2016)

Article Chemistry, Multidisciplinary

Hypoxia Induced by Upconversion-Based Photodynamic Therapy: Towards Highly Effective Synergistic Bioreductive Therapy in Tumors

Yanyan Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Biochemistry & Molecular Biology

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

Nod-Like Receptor Protein-3 Inflammasome Plays an Important Role during Early Stages of Wound Healing

Eileen M. Weinheimer-Haus et al.

PLOS ONE (2015)

Article Pharmacology & Pharmacy

Inhibition of inflammasome activation improves the impaired pattern of healing in genetically diabetic mice

Alessandra Bitto et al.

BRITISH JOURNAL OF PHARMACOLOGY (2014)

Review Biochemistry & Molecular Biology

Mechanisms and Functions of Inflammasomes

Mohamed Lamkanfi et al.

Review Multidisciplinary Sciences

Inflammasomes in health and disease

Till Strowig et al.

NATURE (2012)

Article Oncology

Photodynamic Therapy of Cancer: An Update

Patrizia Agostinis et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2011)

Article Oncology

Successful treatment of refractory facial acne using repeat short-cycle ALA-PDT: Case study

Hui-Lin Ding et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2011)

Review Biochemistry & Molecular Biology

The Inflammasomes

Kate Schroder et al.

Article Oncology

Topical ALA PDT for the treatment of severe acne vulgaris

Xiu-Li Wang et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2010)

Review Dermatology

Inflammation in wound repair: Molecular and cellular mechanisms

Sabine A. Eming et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)