4.6 Article

Sulfolobus islandicus Employs Orc1-2-Mediated DNA Damage Response in Defense against Infection by SSV2

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Summary: Archaeal virus STSV2 interferes with the cell cycle of its host Sulfolobus islandicus, leading to giant cell formation and asymmetric division. The CRISPR-Cas system plays a key role in defending against the virus. This study sheds light on how archaeal viruses manipulate host cells.

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