期刊
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
卷 130, 期 -, 页码 68-80出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jpba.2016.05.044
关键词
Molecularly imprinted polymer; Adsorbent; Separation; Sensor; Pharmaceutical compound
资金
- Environment Research and Technology Development Fund from the Ministry of the Environment, Japan [5-1552]
- Japan Society for the Promotion of Science [15601162, 15K13756]
- Grants-in-Aid for Scientific Research [15K13756] Funding Source: KAKEN
A well-organized molecularly imprinted polymer (MIP) provides the amazing selective molecular recognition ability, which have been close to natural enzymes and antibodies. One of the most efficient applications of MIPs is a selective separation and detection of pharmaceutical compounds in biological and/or environmental samples. MIP-based solid phase extraction now capacitates the selective concentration of the targeting compound from real samples. Also, many of the attractive methodological approaches and applications regarding the analysis of pharmaceutical samples using molecular imprinting technologies (MITs) have been reported in recent years. In this review, we summarize a part of the recent these works related to a new preparation concept of the adsorption adsorbents, sensitive sensor techniques, cell/bacteria separation, and drug delivery system. We believe that our concise summary will be of assistance to additional methodological MITs and highly selective separations/detections. (C) 2016 Elsevier B.V. All rights reserved.
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