4.3 Article

Electrochemical immunosensor nanoarchitectonics with the Ag-rGO nanocomposites for the detection of receptor-binding domain of SARS-CoV-2 spike protein

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Applied

Development of a label free electrochemical sensor based on a sensitive monoclonal antibody for the detection of tiamulin

Aiping Wang et al.

Summary: An electrochemical immunosensor using Ag-GO nanocomposites and AuNPs was developed for the detection of tiamulin, showing enhanced conductivity and a low LOD in a wide linear range. This efficient and simple sensor demonstrated high accuracy in detecting tiamulin in real samples, suggesting its potential as a detection platform for veterinary antibiotics in animal derived foods.

FOOD CHEMISTRY (2022)

Review Immunology

Innate immunological pathways in COVID-19 pathogenesis

Soren R. Paludan et al.

Summary: COVID-19 is a disease characterized by significant dysregulation of the innate immune system. The activation of specific pattern recognition receptors by SARS-CoV-2 and host-derived molecules leads to protective interferon responses and pathological cytokine responses. These pathways are modulated by virus-host interactions and host stress-sensing pathways.

SCIENCE IMMUNOLOGY (2022)

Review Chemistry, Multidisciplinary

Molecular Mechanisms of the Medicines for COVID-19

Makoto Komiyama

Summary: This article surveys the developments of specific medicines for COVID-19, with a focus on their molecular mechanisms of therapeutic actions. Most of these medicines are enzyme inhibitors that selectively hinder critical steps for viral proliferation. However, current medicines have not fully met the requirements to overcome the COVID-19 pandemic, indicating the need for further innovation.

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2022)

Article Virology

Rapid and universal detection of SARS-CoV-2 and influenza A virus using a reusable dual-channel optic fiber immunosensor

Yi Yang et al.

Summary: The study developed a low-cost, easy-to-operate dual-channel optical fiber immunosensor capable of detecting SARS-CoV-2 mutations and multiple influenza A strains. The sensor showed rapid detection, high sensitivity, and specificity, making it a potential on-site screening and surveillance technique for infectious disease.

JOURNAL OF MEDICAL VIROLOGY (2022)

Article Chemistry, Analytical

Amperometric immunosensor developed for sensitive detection of SARS-CoV-2 spike S1 protein in combined with portable device

Arzum Erdem et al.

Summary: In this study, an amperometric immunosensor based on a disposable screen-printed carbon electrode (SPCE) was developed for specific and sensitive detection of SARS-CoV-2 S1 protein. The sensor showed good performance in both buffer medium and artificial saliva medium, with a low limit of detection (LOD) and successful discrimination between S1 protein and HA antigen.

TALANTA (2022)

Article Chemistry, Analytical

Development of a Low-Cost Cotton-Tipped Electrochemical Immunosensor for the Detection of SARS-CoV-2

Shimaa Eissa et al.

Summary: The study presents an electrochemical immunosensor for the detection of SARS-CoV-2 virus antigen, which shows good sensitivity and selectivity by integrating sample collection and detection tools into a single platform. The biosensor offers a promising diagnostic tool for rapid detection of COVID-19 virus antigen in nasal samples.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Rapid SARS-CoV-2 Detection Using Electrochemical Immunosensor

Biljana Mojsoska et al.

Summary: The development of diagnostic tests that can quickly identify infected individuals and assign treatment options is crucial during the COVID-19 pandemic. A proof-of-concept label-free electrochemical immunoassay for rapid detection of SARS-CoV-2 virus via spike surface protein has been introduced, showing high sensitivity for detection and portability for on-site diagnosis.

SENSORS (2021)

Article Biophysics

Multiplex quantitative detection of SARS-CoV-2 specific IgG and IgM antibodies based on DNA-assisted nanopore sensing

Zehui Zhang et al.

Summary: The article introduces a new serologic assay method utilizing DNA-assisted nanopore sensing for quantification of SARS-CoV-2 antibodies in human serum. This technology provides higher accuracy, larger dynamic range, and potential for automated testing compared to current clinically used point-of-care assays and ELISA assays.

BIOSENSORS & BIOELECTRONICS (2021)

Review Chemistry, Multidisciplinary

Molecular-Level Anatomy of SARS-CoV-2 for the Battle against the COVID-19 Pandemic

Makoto Komiyama

Summary: The article discusses the chemical information on COVID-19, focusing on molecular-level understanding of the virus, including the basics of the causative pathogen, the molecular structure of the spike on the viral surface, and the binding mode of these spikes to human cell receptors. By delving into the conformational changes of spike proteins and the impact of SARS-CoV-2 mutations on pathogenicity, the article helps readers gain a better understanding of COVID-19.

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2021)

Article Chemistry, Analytical

A sandwich-type electrochemical immunosensor using rGO-TEPA-Thi-Au as sensitive platform and CMK-3@AuPtNPs as signal probe for AFP detection

Haolin Xiao et al.

Summary: In this study, a highly sensitive electrochemical immunosensor was developed for the effective detection of the cancer marker AFP. The platform modified with Thi and AuNPs, along with the signal probe CMK-3@AuPtNPs, resulted in improved sensitivity and signal amplification. The immunosensor demonstrated a wide linear range, low detection limit, excellent stability, and recovery, showcasing its potential for clinical applications.

MICROCHEMICAL JOURNAL (2021)

Review Oncology

COVID-19: immunopathology, pathophysiological mechanisms, and treatment options

Larissa E. van Eijk et al.

Summary: COVID-19, caused by SARS-CoV-2, is a complex viral disease with varying symptoms, understanding its immunopathology and developing effective treatment strategies are crucial. Pathological observations provide valuable insights, current management strategies include supportive care and drug therapy.

JOURNAL OF PATHOLOGY (2021)

Article Chemistry, Analytical

Highly selective and sensitive sandwich immunosensor platform modified with MUA-capped GNPs for detection of spike Receptor Binding Domain protein: A precious marker of COVID 19 infection

Elif Burcu Aydin et al.

Summary: A label-free electrochemical biosensing system was developed for the diagnosis of coronavirus with a novel production procedure for the fabrication of gold nanoparticles-capped bioelectrode. The bioelectrode showed promising application potential for RBD biosensing by forming covalent ester linking between hydroxylated ITO electrode and GNPs-capped MUA.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Article Chemistry, Analytical

Development of a SERS-based lateral flow immunoassay for rapid and ultra-sensitive detection of anti-SARS-CoV-2 IgM/IgG in clinical samples

Haifeng Liu et al.

Summary: This study reported a surface-enhanced Raman scattering-based lateral flow immunoassay method for the high sensitivity simultaneous detection of anti-SARS-CoV-2 IgM/IgG. The method utilized custom SERS tags and dual layers of Raman dye, with signal intensities easily recorded by a portable Raman instrument for high sensitivity analysis. Validation on samples from COVID-19 patients and healthy individuals showed high accuracy and specificity.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Article Chemistry, Analytical

Dual mode competitive electrochemical immunoassay for dibutyl phthalate detection based on PEI functionalized nitrogen doped graphene-CoSe2/gold nanowires and thionine-Au@Pt core-shell

Jiawen Li et al.

Summary: A sensitive dual mode competitive electrochemical immunosensor for quantitative determination of dibutyl phthalate (DBP) was successfully developed. It utilized signal amplification and multiple detection methods to achieve highly sensitive detection of DBP in real samples.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Article Medicine, General & Internal

Simpler and faster Covid-19 testing: Strategies to streamline SARS-CoV-2 molecular assays

Nuttada Panpradist et al.

Summary: A low-cost RT-PCR kit was developed for faster detection of SARS-CoV-2 infections, with high sensitivity and specificity demonstrated in both laboratory and clinical settings. The assay showed promising performance and could potentially expand access to Covid-19 testing.

EBIOMEDICINE (2021)

Article Medicine, General & Internal

Accuracy of a Novel SARS-CoV-2 Antigen-Detecting Rapid Diagnostic Test from Standardized Self-Collected Anterior Nasal Swabs

Bilgin Osmanodja et al.

Summary: A novel Ag-RDT for anterior nasal self-collection has been validated with high sensitivity and specificity, providing a valuable alternative for sample collection.

JOURNAL OF CLINICAL MEDICINE (2021)

Review Microbiology

Coronavirus biology and replication: implications for SARS-CoV-2

Philip V'kovski et al.

Summary: This review discusses key aspects of coronavirus biology and their implications for SARS-CoV-2 infections, treatment, and prevention strategies. Understanding virus-host interactions at the molecular level is crucial for developing effective intervention strategies. Summarizing the discoveries of SARS-CoV-2 infection and comparing it with other coronaviruses will support future preparedness and combat strategies.

NATURE REVIEWS MICROBIOLOGY (2021)

Review Biochemistry & Molecular Biology

A systematic review of SARS-CoV-2 vaccine candidates

Yetian Dong et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Review Engineering, Biomedical

Electrochemical biosensors: perspective on functional nanomaterials for on-site analysis

Il-Hoon Cho et al.

BIOMATERIALS RESEARCH (2020)

Article Chemistry, Analytical

A voltammetric immunosensor for clenbuterol based on the use of a MoS2-AuPt nanocomposite

Renyue Ji et al.

MICROCHIMICA ACTA (2018)

Article Nanoscience & Nanotechnology

Fully Printed, Rapid-Response Sensors Based on Chemically Modified Graphene for Detecting NO2 at Room Temperature

Lei Huang et al.

ACS APPLIED MATERIALS & INTERFACES (2014)

Article Nanoscience & Nanotechnology

Oxidative stress-mediated antibacterial activity of graphene oxide and reduced graphene oxide in Pseudomonas aeruginosa

Sangiliyandi Gurunathan et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2012)

Article Chemistry, Physical

Facile Synthesis and Application of Ag-Chemically Converted Graphene Nanocomposite

Jianfeng Shen et al.

NANO RESEARCH (2010)

Article Chemistry, Physical

Single sheet functionalized graphene by oxidation and thermal expansion of graphite

Michael J. McAllister et al.

CHEMISTRY OF MATERIALS (2007)

Article Multidisciplinary Sciences

Preparation and characterization of graphene oxide paper

Dmitriy A. Dikin et al.

NATURE (2007)