☆ 4.1 Article

A proof of concept reinforcement learning based tool for non parametric population pharmacokinetics workflow optimization

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2023)

An Algorithm for Nonparametric Estimation of a Multivariate Mixing Distribution with Applications to Population Pharmacokinetics

Walter M. Yamada et al.

Summary: Population pharmacokinetic modeling is essential for drug development and optimal dosing. Our nonparametric maximum likelihood method allows for estimating multivariate mixing distributions without assumptions about shape. This approach is discrete and applicable to high-dimensional mixture models.

PHARMACEUTICS (2021)

添加到收藏夹

Article Mathematics, Applied

Julia: A Fresh Approach to Numerical Computing

Jeff Bezanson et al.

SIAM REVIEW (2017)

添加到收藏夹

Review Pharmacology & Pharmacy

Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification

Jennifer E. Sager et al.

DRUG METABOLISM AND DISPOSITION (2015)

添加到收藏夹

Article Pharmacology & Pharmacy

Enhancing population pharmacokinetic modeling efficiency and quality using an integrated workflow

Henning Schmidt et al.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2014)

添加到收藏夹

A proof of concept reinforcement learning based tool for non parametric population pharmacokinetics workflow optimization

相关参考文献

An Algorithm for Nonparametric Estimation of a Multivariate Mixing Distribution with Applications to Population Pharmacokinetics

Julia: A Fresh Approach to Numerical Computing

Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification

Enhancing population pharmacokinetic modeling efficiency and quality using an integrated workflow

导出引文

分享论文