Quality evaluation of berberine food supplements with high-field and compact 1H NMR spectrometers

Article Chemistry, Applied

Rapid determination and optimisation of berberine from HimalayanBerberis lyciumby soxhlet apparatus using CCD-RSM and its quality control as a potential candidate for COVID-19

Anil Kumar Katare et al.

Summary: Berberis plants, particularly berberine, have shown potential in treating COVID-19. A rapid determination and extraction method for berberine has been developed using the central composite design-response surface methodology.

NATURAL PRODUCT RESEARCH (2022)

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Article Chemistry, Analytical

Quality assessment of Curcuma dietary supplements: Complementary data from LC-MS and 1H NMR

Sothearath Sorng et al.

Summary: This study evaluated the quality of turmeric dietary supplements by analyzing their chemical composition using UHPLC-MS and H-1 NMR. The results showed significant variability in the composition of these supplements and found that the actual quantities of curcuminoids and piperine in the supplements often did not match the claimed amounts.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2022)

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Review Chemistry, Inorganic & Nuclear

Recent Applications of Benchtop Nuclear Magnetic Resonance Spectroscopy

Hyo-Yeon Yu et al.

Summary: Benchtop nuclear magnetic resonance (NMR) spectroscopy utilizes small permanent magnets to generate magnetic fields, offering operational simplicity and cost efficiency as an alternative to high-field NMR spectroscopy. It has found diverse applications in fields such as food science, pharmaceuticals, and reaction monitoring.

MAGNETOCHEMISTRY (2021)

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Article Medicine, Research & Experimental

Efficacy and safety of berberine for dyslipidemia: study protocol for a randomized double-blind placebo-controlled trial

Ying Zhao et al.

Summary: This study is a randomized, double-blind, and placebo-controlled clinical trial to evaluate the efficacy and safety of berberine for dyslipidemia. It aims to determine the effectiveness and safety of berberine in treating dyslipidemia by measuring primary outcomes such as the percentage of low-density lipoprotein cholesterol reduction at week 12.

TRIALS (2021)

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Review Biochemistry & Molecular Biology

An insight into the medicinal attributes of berberine derivatives: A review

Sobhi Gaba et al.

Summary: Berberine, a plant-derived isoquinoline alkaloid, has shown remarkable therapeutic diversity and potential for the discovery of new therapeutic agents. Despite its clinical utility being compromised by undesirable pharmacokinetic properties, structural modifications have been made to improve its therapeutic efficacy, leading to significant advancements in its medicinal chemistry. This review provides a comprehensive overview of recent advancements in the field and serves as a valuable guide for the rational design of berberine-based compounds.

BIOORGANIC & MEDICINAL CHEMISTRY (2021)

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Article Chemistry, Analytical

A validated high-performance thin-layer chromatography method for the simultaneous estimation of berberine, berbamine, palmatine, magnoflorine and jatrorrhizine from Berberis aristata

Ishita A. Basera et al.

Summary: Indian barberry, a medicinal herb native to the Northern Himalaya, has different pharmacological and therapeutic effects, with important bioactive constituents including berberine. A validated simultaneous high-performance thin-layer chromatography method has been developed for the concurrent estimation of five representative biomarkers of B. aristata, aiding in its qualitative analysis.

JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC (2021)

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Article Biochemistry & Molecular Biology

Analysis of Monacolins and Berberine in Food Supplements for Lipid Control: An Overview of Products Sold on the Italian Market

Sara Marcheluzzo et al.

Summary: The use of dietary supplements for the prevention and management of diseases associated with excess of lipids is increasing in Western countries. However, there is a lack of standardization of active ingredients in supplements containing red yeast rice and extracts from Berberis species, highlighting the need for strict regulation and monitoring.

MOLECULES (2021)

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Article Biochemistry & Molecular Biology