相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
Sudabeh Alatab et al.
LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)
FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells
Robin Schwarzer et al.
IMMUNITY (2020)
Pathophysiology of Inflammatory Bowel Diseases
John T. Chang
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses
Daisuke Oikawa et al.
COMMUNICATIONS BIOLOGY (2020)
Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease
Matthias Friedrich et al.
IMMUNITY (2019)
Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment
Christina Eftychi et al.
IMMUNITY (2019)
Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD
Yi Rang Na et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)
ABIN-2, of the TPL-2 Signaling Complex, Modulates Mammalian Inflammation
Louise V. Webb et al.
TRENDS IN IMMUNOLOGY (2019)
NF-κB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells
Lauren G. Jones et al.
CELL DEATH & DISEASE (2019)
Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice
Johanna Pott et al.
CELL HOST & MICROBE (2018)
Crucial Role of Linear Ubiquitin Chain Assembly Complex-Mediated Inhibition of Programmed Cell Death in TLR4-Mediated B Cell Responses and B1b Cell Development
Yoshiteru Sasaki et al.
JOURNAL OF IMMUNOLOGY (2018)
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
Nieves Peltzer et al.
NATURE (2018)
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
Lucia Taraborrelli et al.
NATURE COMMUNICATIONS (2018)
Linear ubiquitination of cFLIP induced by LUBAC contributes to TNF-induced apoptosis
Yong Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Origin, Differentiation, and Function of Intestinal Macrophages
Calum C. Bain et al.
FRONTIERS IN IMMUNOLOGY (2018)
Current and emerging therapeutic targets for IBD
Markus F. Neurath
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis
Derrick D. Eichele et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2017)
Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease
J. Kenneth Baillie et al.
PLOS GENETICS (2017)
NF-kappa B signaling in inflammation
Ting Liu et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2017)
Reparative inflammation takes charge of tissue regeneration
Michael Karin et al.
NATURE (2016)
Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι
Yuki Nakanishi et al.
CELL REPORTS (2016)
Perturbations of mucosal homeostasis through interactions of intestinal microbes with myeloid cells
Regina Schey et al.
IMMUNOBIOLOGY (2015)
Immunopathogenesis of IBD: current state of the art
Heitor S. P. de Souza et al.
Nature Reviews Gastroenterology & Hepatology (2015)
EP4 Receptor-Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis
Masato Nakatsuji et al.
PLoS Genetics (2015)
Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways
Claudia Guenther et al.
GUT (2015)
Innate and adaptive immunity in inflammatory bowel disease
Alessandra Geremia et al.
AUTOIMMUNITY REVIEWS (2014)
Macrophages in intestinal homeostasis and inflammation
Calum C. Bain et al.
IMMUNOLOGICAL REVIEWS (2014)
RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
Nozomi Takahashi et al.
NATURE (2014)
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
Marius Dannappel et al.
NATURE (2014)
A20 controls intestinal homeostasis through cell-specific activities
Lars Vereecke et al.
NATURE COMMUNICATIONS (2014)
HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death
Nieves Peltzer et al.
CELL REPORTS (2014)
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
James A. Rickard et al.
ELIFE (2014)
Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
Snehlata Kumari et al.
ELIFE (2014)
Cytokines in inflammatory bowel disease
Markus F. Neurath
NATURE REVIEWS IMMUNOLOGY (2014)
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
Lance W. Peterson et al.
NATURE REVIEWS IMMUNOLOGY (2014)
A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide
Jonathan M. Williams et al.
DISEASE MODELS & MECHANISMS (2013)
Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells
Yoshiteru Sasaki et al.
EMBO JOURNAL (2013)
TNF-alpha-induced intestinal epithelial cell shedding: implications for intestinal barrier function
Alastair J. M. Watson et al.
BARRIERS AND CHANNELS FORMED BY TIGHT JUNCTION PROTEINS II (2012)
IκB kinase regulation of the TPL-2/ERK MAPK pathway
Thorsten Gantke et al.
IMMUNOLOGICAL REVIEWS (2012)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins et al.
NATURE (2012)
Intestinal macrophages and response to microbial encroachment
P. D. Smith et al.
MUCOSAL IMMUNOLOGY (2011)
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
Patrick-Simon Welz et al.
NATURE (2011)
Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
Claudia Guenther et al.
NATURE (2011)
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
Fumiyo Ikeda et al.
NATURE (2011)
Enterocyte death and intestinal barrier maintenance in homeostasis and disease
Lars Vereecke et al.
TRENDS IN MOLECULAR MEDICINE (2011)
Linear polyubiquitination: a new regulator of NF-κB activation
Kazuhiro Iwai et al.
EMBO REPORTS (2009)
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
Toshiro Sato et al.
NATURE (2009)
Involvement of linear polyubiquitylation of NEMO in NF-κB activation
Fuminori Tokunaga et al.
NATURE CELL BIOLOGY (2009)
Intestinal mucosal barrier function in health and disease
Jerrold R. Turner
NATURE REVIEWS IMMUNOLOGY (2009)
Regulation of tissue homeostasis by NF-κB signalling: implications for inflammatory diseases
Manolis Pasparakis
NATURE REVIEWS IMMUNOLOGY (2009)
NF-κB in inflammatory bowel disease
I. Atreya et al.
JOURNAL OF INTERNAL MEDICINE (2008)
Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
David Artis
NATURE REVIEWS IMMUNOLOGY (2008)
Epithelial NEMO links innate immunity to chronic intestinal inflammation
Arianna Nenci et al.
NATURE (2007)
A ubiquitin ligase complex assembles linear polyubiquitin chains
Takayoshi Kirisako et al.
EMBO JOURNAL (2006)
Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis
RB Sartor
NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY (2006)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
FR Greten et al.
CELL (2004)
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium
F El Marjou et al.
GENESIS (2004)