Organocalcium Hydride-Catalyzed Intramolecular C(sp3)-H Annulation of Functionalized 2,6-Lutidines

Article Chemistry, Physical

Calcium Mediated C-H Silylation of Aromatic Heterocycles with Hydrosilanes

Xun Gong et al.

Summary: This study demonstrates that a series of aromatic heterocycles can undergo regioselective C-H silylation under mild conditions by using compound 1.

CHEMCATCHEM (2022)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Calcium-catalyzed C(sp)-H silylation of terminal alkynes with hydrosilanes

Xizhou Zheng et al.

Summary: This work presents a C(sp)-H silylation of terminal alkynes with hydrosilanes using a molecular calcium hydride catalyst. The reaction demonstrates high selectivity and yield with a broad range of substrates, showing high atom efficiency. Control experiments and kinetic studies provide insights into the catalytic reaction mechanism.

POLYHEDRON (2022)

添加到收藏夹

Article Chemistry, Physical

Regioselective C-H Alkylation of Aromatic Ethers with Alkenes by a Half-Sandwich Calcium Catalyst

Lanxiao Zhao et al.

Summary: This study demonstrated the catalytic ortho-regioselective C-H alkylation of alkoxy-substituted benzene derivatives with alkenes using a half-sandwich calcium alkyl complex as the precatalyst. The potential catalytic reaction intermediates were isolated and X-ray structurally characterized, with DFT calculations elucidating the different reaction profiles of sp(2) and sp(3) C-H activations.

ACS CATALYSIS (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Metal-catalysed C-H bond activation and borylation

Ranjana Bisht et al.

Summary: Transition metal-catalysed direct borylation of hydrocarbons via C-H bond activation has gained significant attention for its synthetic versatility. Selectivity control is a challenging issue, but recent efforts have led to impressive progress in both proximal and distal C-H bond borylation reactions. Innovative methodologies have been developed for ortho C-H bond borylation reactions, while meta and para selective reactions remain a challenge. Advancements have also been made for aliphatic C(sp(3))-H borylations and enantioselective borylations. This review discusses the development of different approaches and findings since 2014, as well as various applications of C-H borylation reactions in the synthesis of natural products, therapeutics, and materials chemistry.

CHEMICAL SOCIETY REVIEWS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Diastereoselective synthesis of tetrahydrobenzo[b]azocines by Lu(OTf)3-catalyzed [4+4] cycloaddition of donor-acceptor cyclobutanes with anthranils

Meifeng Hou et al.

Summary: In this study, the construction of N-heterocyclic eight-membered rings using Lu(OTf)(3) as a catalyst is reported. A formal [4+4] cycloaddition reaction of cyclobutane 1,1-diesters with anthranils was used to deliver oxa-bridged eight-membered heterocycles, providing a potential method for building complex azocine compounds.

CHEMICAL COMMUNICATIONS (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Construction of Medium-Sized Rings by Gold Catalysis

Ronald L. Reyes et al.

Summary: This review focuses on methodologies for constructing medium-sized rings using gold catalysis, particularly emphasizing the pathway, precursor selection, catalyst choice, and mechanistic attributes. Gold-mediated cyclization reactions show significant potential in building 7-membered rings and medium-sized (8-11-membered) ring structures.

CHEMICAL REVIEWS (2021)

添加到收藏夹

Article Chemistry, Physical

Highly Diastereo- and Enantioselective Synthesis of Tetrahydrobenzo[b]azocines via Palladium-Catalyzed [4+4] Cycloaddition

Can Gao et al.

Summary: This study presents a palladium-catalyzed asymmetric [4 + 4] cycloaddition, allowing for efficient synthesis of highly stereochemically controlled nitrogen-heterocyclic compounds. The method provides good regio-, stereo-, and enantioselectivity, with the ability to tolerate complex substrates derived from natural products.

ACS CATALYSIS (2021)

添加到收藏夹

Article Chemistry, Physical

Calcium-Catalyzed Dehydrogenative Silylation of Aromatic Ethers with Hydrosilane

Lanxiao Zhao et al.

Summary: This study demonstrated the catalytic regioselective C-H silylation of alkoxy-substituted benzene derivatives using a specific calcium complex, offering an efficient and direct method for synthesizing silyl-substituted aromatic ether derivatives while avoiding transition metal. Proposed calcium anisyl complexes were isolated and structurally characterized as catalytic reaction intermediates.

ACS CATALYSIS (2021)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Calcium-mediated C(sp3)-H Activation and Alkylation of Alkylpyridines

Xizhou Zheng et al.

Summary: Calcium-mediated reaction successfully catalyzes regioselective benzylic C-H bond addition of alkylpyridines, resulting in alkylated pyridine derivatives.

INORGANIC CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A photochemical ring expansion of 6-to 8-membered nitrogen heterocycles by [1,3]-sigmatropic rearrangement

Morgan A. Manning et al.

Summary: A new route to azocines and benzoazocines from furopyridinones is described through a photochemically induced [1,3]-sigmatropic rearrangement. The method provides excellent atom economy by sequencing thermal and photochemical ring expansion steps under continuous flow.

CHEMICAL COMMUNICATIONS (2021)

添加到收藏夹

Article Chemistry, Applied

Rare-Earth-Metal-Catalyzed Synthesis of Azaindolines and Naphthyridines via C-H Cyclization of Functionalized Pyridines

Pengqing Ye et al.

ADVANCED SYNTHESIS & CATALYSIS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Calcium Hydride Reduction of Polycyclic Aromatic Hydrocarbons

Andrew S. S. Wilson et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mononuclear calcium complex as effective catalyst for alkenes hydrogenation

Xianghui Shi et al.

CHEMICAL COMMUNICATIONS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Regio- and Enantioselective C-H Cyclization of Pyridines with Alkenes Enabled by a Nickel/N-Heterocyclic Carbene Catalysis

Wu-Bin Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Calcium-Catalyzed Arene C-H Bond Activation by Low-Valent AlI

Steffen Brand et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

3d Transition Metals for C-H Activation

Parthasarathy Gandeepan et al.

CHEMICAL REVIEWS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Reduction of 1,3,5,7-cyclooctatetraene by a molecular calcium hydride: an even electron polarised insertion/deprotonation mechanism

Michael S. Hill et al.

CHEMICAL COMMUNICATIONS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Potassium Amide-Catalyzed Benzylic C-H Bond Addition of Alkylpyridines to Styrenes

Dan-Dan Zhai et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Platinum-Catalyzed C-H Functionalization

Jay A. Labinger

CHEMICAL REVIEWS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Formal Allylic C(sp3)-H Bond Activation of Alkenes Triggered by a Sodium Amide

Wei Bao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

B(C6F5)3-Catalyzed (Convergent) Disproportionation Reaction of lndoles

Yuxi Han et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Enantioselective Phosphine-Catalyzed Formal [4+4] Annulation of α,β-Unsaturated Imines and Allene Ketones: Construction of Eight-Membered Rings

Huanzhen Ni et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Calcium Hydride Cation [CaH]+ Stabilized by an NNNN-type Macrocyclic Ligand: A Selective Catalyst for Olefin Hydrogenation

Danny Schuhknecht et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Transition-Metal-Catalyzed C-H Alkylation Using Alkenes

Zhe Dong et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Metal-Organic Cooperative Catalysis in C-H and C-C Bond Activation

Dong-Su Kim et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Organocatalysis in Inert C-H Bond Functionalization

Yan Qin et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Iron-Catalyzed C-H Bond Activation

Rui Shang et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

(C6F5)3B Catalyzed Chemoselective and ortho-Selective Substitution of Phenols with α-Aryl α-Diazoesters

Zhunzhun Yu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Alkaline earths as main group reagents in molecular catalysis

Michael S. Hill et al.

CHEMICAL SOCIETY REVIEWS (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Transition metal-catalysed couplings between arenes and strained or reactive rings: combination of C-H activation and ring scission

Fen Wang et al.

CHEMICAL SOCIETY REVIEWS (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Asymmetric Ruthenium-Catalyzed Hydrogenation of 2,6-Disubstituted 1,5-Naphthyridines: Access to Chiral 1,5-Diaza-cis-Decalins

Jianwei Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Calcium Hydride Catalyzed Highly 1,2-Selective Pyridine Hydrosilylation

Julia Intemann et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Metal-free catalytic C-H bond activation and borylation of heteroarenes

Marc-Andre Legare et al.

SCIENCE (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Rhodium-catalyzed C-H functionalization-based approach to eight-membered lactams

Shangze Wu et al.

CHEMICAL SCIENCE (2015)

添加到收藏夹

Article Chemistry, Medicinal

Update on the Discovery and Development of Cholesteryl Ester Transfer Protein Inhibitors for Reducing Residual Cardiovascular Risk

Nathan B. Mantlo et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Scope and mechanism of asymmetric C(sp3)-H/C(Ar)-X coupling reactions: computational and experimental study

Evgeny Larionov et al.

CHEMICAL SCIENCE (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Cationic Calcium Hydride Cluster Stabilized by Cyclen-Derived Macrocyclic N,N,N,N Ligands

Phillip Jochmann et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

添加到收藏夹

Article Chemistry, Medicinal

Design, synthesis and structure-activity-relationship of 1,5-tetrahydronaphthyridines as CETP inhibitors

Maria-Carmen Fernandez et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

Ruthenium(II)-Catalyzed C-H Bond Activation and Functionalization

Percia Beatrice Arockiam et al.

CHEMICAL REVIEWS (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

From Limestone to Catalysis: Application of Calcium Compounds as Homogeneous Catalysts

Sjoerd Harder

CHEMICAL REVIEWS (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

Intramolecular Hydroamination of Aminoalkenes by Calcium and Magnesium Complexes: A Synthetic and Mechanistic Study

Mark R. Crimmin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

添加到收藏夹

Article Chemistry, Multidisciplinary

Early Main-Group Metal Catalysts for the Hydrogenation of Alkenes with H-2

Jan Spielmann et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

添加到收藏夹

Article Chemistry, Multidisciplinary

Rational design of a well-defined soluble calcium hydride complex

Sjoerd Harder et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis of medium ring nitrogen heterocycles via a tandem copper-catalyzed C-N bond formation - Ring-expansion process

A Klapars et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

添加到收藏夹

Organocalcium Hydride-Catalyzed Intramolecular C(sp3)-H Annulation of Functionalized 2,6-Lutidines

相关参考文献

导出引文

分享论文