4.6 Review

Psychiatric symptoms in multiple sclerosis: a biological perspective on synaptic and network dysfunction

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Clinical Neurology

Fatigue, depression, and pain in multiple sclerosis: How neuroinflammation translates into dysfunctional reward processing and anhedonic symptoms

Henrik Heitmann et al.

Summary: Fatigue, depression, and pain are common symptoms in multiple sclerosis (MS) patients, with recent neuroimaging and neuroimmunological findings suggesting that dysfunctional reward processing may represent a shared mechanism for these symptoms. Therapeutic focus on monoaminergic neurotransmission is key, but current treatments have limitations in addressing these symptoms effectively.

MULTIPLE SCLEROSIS JOURNAL (2022)

Review Clinical Neurology

Psychiatric disorders in multiple sclerosis

Sparaco Maddalena et al.

Summary: The article discusses the common psychiatric symptoms in people with MS and their impact factors, such as depression, bipolar disorder, anxiety, schizophrenia, and obsessive-compulsive symptoms. It also mentions some radiological studies on PD, emphasizing the common features of gray matter atrophy, white matter abnormalities, and corpus callosum involvement in MS and PD.

JOURNAL OF NEUROLOGY (2021)

Article Clinical Neurology

Depression is associated with disconnection of neurotransmitter-related nuclei in multiple sclerosis

Matteo Martino et al.

Summary: Depression in multiple sclerosis patients is associated with reduced functional connectivity of neurotransmitter-related brainstem nuclei, as well as distinct alterations in white matter microstructure, primarily involving the limbic network.

MULTIPLE SCLEROSIS JOURNAL (2021)

Article Cell Biology

Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis

Massimiliano Di Filippo et al.

Summary: The study reveals a possible link between IL-17A and hippocampal function, with IL-17A disrupting hippocampal long-term potentiation and showing correlation with dysfunction in EAE. Mice lacking IL-17A exhibit preserved visuo-spatial learning abilities in the presence of EAE.

CELL REPORTS (2021)

Review Biochemistry & Molecular Biology

Insights into the Pathophysiology of Psychiatric Symptoms in Central Nervous System Disorders: Implications for Early and Differential Diagnosis

Giulia Menculini et al.

Summary: Psychiatric symptoms are common in neurological diseases and can often be the first clinical manifestations, emphasizing the importance of a coordinated diagnostic approach between neurologists and psychiatrists.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Psychiatry

Prevalence of bipolar disorder in multiple sclerosis: a systematic review and meta-analysis

Boney Joseph et al.

Summary: A systematic review and meta-analysis on the prevalence of bipolar disorder (BD) in adults with multiple sclerosis (MS) found that the pooled prevalence rate of BD in MS patients was 2.95%, with higher prevalence in the Americas compared to Europe. Subgroup analysis showed a higher prevalence of BD in females with MS (7.03%) than in males (5.64%), but this difference was not statistically significant.

EVIDENCE-BASED MENTAL HEALTH (2021)

Article Clinical Neurology

Impaired connectivity within neuromodulatory networks in multiple sclerosis and clinical implications

Antonio Carotenuto et al.

JOURNAL OF NEUROLOGY (2020)

Article Clinical Neurology

Bipolar disorders and deep grey matter in multiple sclerosis: A preliminary quantitative MRI study

L. Lorefice et al.

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2020)

Article Clinical Neurology

Fronto-limbic disconnection in patients with multiple sclerosis and depression

Quinten van Geest et al.

MULTIPLE SCLEROSIS JOURNAL (2019)

Article Clinical Neurology

Fronto-limbic disconnection in patients with multiple sclerosis and depression

Quinten van Geest et al.

MULTIPLE SCLEROSIS JOURNAL (2019)

Article Clinical Neurology

Use of coping strategies in multiple sclerosis: Association with demographic and disease-related characteristics

D. P. Holland et al.

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2019)

Review Medicine, General & Internal

Multiple sclerosis

Alan J. Thompson et al.

LANCET (2018)

Review Neurosciences

Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease

Evanthia Nanou et al.

NEURON (2018)

Article Clinical Neurology

Pulse steroid therapy in multiple sclerosis and mood changes: An exploratory prospective study

Lorena Lorefice et al.

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2018)

Review Neurosciences

Multiple sclerosis and cognition: synaptic failure and network dysfunction

Massimiliano Di Filippo et al.

NATURE REVIEWS NEUROSCIENCE (2018)

Article Clinical Neurology

Default mode network changes in multiple sclerosis: a link between depression and cognitive impairment?

S. Bonavita et al.

EUROPEAN JOURNAL OF NEUROLOGY (2017)

Review Clinical Neurology

Neuropsychiatric syndromes of multiple sclerosis

Ruth Murphy et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2017)

Review Clinical Neurology

Prevalence of depression and anxiety in Multiple Sclerosis: A systematic review and meta-analysis

Rosa E. Boeschoten et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2017)

Article Clinical Neurology

Gray matter trophism, cognitive impairment, and depression in patients with multiple sclerosis

Emanuele Pravata et al.

MULTIPLE SCLEROSIS JOURNAL (2017)

Article Clinical Neurology

Gray matter trophism, cognitive impairment, and depression in patients with multiple sclerosis

Emanuele Pravata et al.

MULTIPLE SCLEROSIS JOURNAL (2017)

Review Clinical Neurology

The varieties of psychosis in multiple sclerosis: A systematic review of cases

Carlos R. Camara-Lemarroy et al.

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2017)

Article Clinical Neurology

The spectrum of psychosis in multiple sclerosis: a clinical case series

Thomas G. Gilberthorpe et al.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2017)

Review Pharmacology & Pharmacy

Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity

Danielle M. Gerhard et al.

DRUG DISCOVERY TODAY (2016)

Article Multidisciplinary Sciences

Persistent activation of microglia and NADPH drive hippocampal dysfunction in experimental multiple sclerosis

Massimiliano Di Filippo et al.

SCIENTIFIC REPORTS (2016)

Article Neurosciences

Hippocampal-DMN Disconnectivity in MS is Related to WM Lesions and Depression

Maria A. Rocca et al.

HUMAN BRAIN MAPPING (2015)

Review Clinical Neurology

The incidence and prevalence of psychiatric disorders in multiple sclerosis: A systematic review

Ruth Ann Marrie et al.

MULTIPLE SCLEROSIS JOURNAL (2015)

Review Clinical Neurology

The incidence and prevalence of psychiatric disorders in multiple sclerosis: A systematic review

Ruth Ann Marrie et al.

MULTIPLE SCLEROSIS JOURNAL (2015)

Article Psychology, Clinical

Predictors of Anxiety in Multiple Sclerosis

Narineh Hartoonian et al.

REHABILITATION PSYCHOLOGY (2015)

Article Neurosciences

Effects of central and peripheral inflammation on hippocampal synaptic plasticity

Massimiliano Di Filippo et al.

NEUROBIOLOGY OF DISEASE (2013)

Article Neurosciences

Neuroplasticity in Depressed Individuals Compared with Healthy Controls

Michael J. Player et al.

NEUROPSYCHOPHARMACOLOGY (2013)

Article Neurosciences

TNF-α-mediated anxiety in a mouse model of multiple sclerosis

Nabila Haji et al.

EXPERIMENTAL NEUROLOGY (2012)

Article Clinical Neurology

Diffusion tensor imaging abnormalities in depressed multiple sclerosis patients

A. Feinstein et al.

MULTIPLE SCLEROSIS JOURNAL (2010)

Article Clinical Neurology

Default-mode network dysfunction and cognitive impairment in progressive MS

M. A. Rocca et al.

NEUROLOGY (2010)

Review Neurosciences

LTP and LTD: An embarrassment of riches

RC Malenka et al.

NEURON (2004)

Article Clinical Neurology

Depression and anxiety in multiple sclerosis. A clinical and MRI study in 95 subjects

M Zorzon et al.

JOURNAL OF NEUROLOGY (2001)