Ultrasonic-assisted extraction-synergistic deep eutectic solvents for green and efficient incremental extraction of Paris polyphylla saponins

Article Plant Sciences

Polyphyllin D induces apoptosis and protective autophagy in breast cancer cells through JNK1-Bcl-2 pathway

Jiazhe Liu et al.

Summary: The study found that Polyphyllin D (PD) can induce autophagy in breast cancer cells through activation of the JNK1/Bcl-2 pathway, and increase PD-induced cell apoptosis by inhibiting autophagy, thus achieving anti-tumor effects.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

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Review Multidisciplinary Sciences

Bioactive secondary metabolites in Paris polyphylla Sm. and their biological activities: A review

Chandra Bahadur Thapa et al.

Summary: Paris polyphylla contains bioactive secondary metabolites such as Paris saponins, which have demonstrated antioxidant, anticancer, antifungal properties. This review paper summarizes the importance of these bioactive components for research and drug development.

HELIYON (2022)

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Article Chemistry, Applied

Integrated natural deep eutectic solvent and pulse-ultrasonication for efficient extraction of crocins from gardenia fruits (Gardenia jasminoides Ellis) and its bioactivities

Hao Huang et al.

Summary: This study proposed a green strategy, using natural deep eutectic solvent (NADES) based pulse-ultrasonication-assisted extraction (PUAE), to efficiently extract crocins from gardenia fruits. The optimized conditions led to the maximum yield of crocins, and UPLC-Triple-TOF/MS identified crocetin as the main compound.

FOOD CHEMISTRY (2022)

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Article Biochemistry & Molecular Biology

Deep Eutectic Solvent as Green Solvent in Extraction of Biological Macromolecules: A Review

Jordy Kim Ung Ling et al.

Summary: Greater awareness of environmental sustainability has led to the transition from synthetic organic solvents to greener solvents in various industries. Deep eutectic solvents (DESs), with their demonstrated applications in extraction of small-molecule bioactive compounds, are considered highly promising green solvents. However, the use of DES in biomacromolecule extraction has not been extensively studied. This review provides an overview of DES properties and discusses recent advances in DES extraction of proteins, carbohydrates, and lipids. It also highlights the importance of DES properties on extraction performance and identifies future research needs.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Article Agricultural Engineering

Comprehensive utilization of corncob for furfuryl alcohol production by chemo-enzymatic sequential catalysis in a biphasic system

Chong-Yang Bu et al.

Summary: A new process for producing furfuryl alcohol from corncob was proposed using deep eutectic solvents and whole cell catalysis. The process involved pretreating corncob with deep eutectic solvents to convert xylan into furfural, enzymatic hydrolysis to obtain glucose-rich enzymatic hydrolysate, and using NADH for furfural reduction. The final furfuryl alcohol yield reached 20.7% with corncob as substrate, demonstrating high-value production and comprehensive utilization of corncob.

BIORESOURCE TECHNOLOGY (2021)

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Article Chemistry, Applied

Ultrasound-assisted development of stable grapefruit peel polyphenolic nano-emulsion: Optimization and application in improving oxidative stability of mustard oil

Jyoti Nishad et al.

Summary: The study demonstrated the feasibility of fabricating stable grapefruit-peel-phenolic nano-emulsion in mustard oil through the assistance of ultrasonication and Span-80. This method provides a basic guideline for formulating stable nano-emulsions for use in active food packaging, oils, and pharmaceuticals.

FOOD CHEMISTRY (2021)

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Review Agriculture, Multidisciplinary

Review on Extraction of Phenolic Compounds from Natural Sources Using Green Deep Eutectic Solvents

Ali Ali Redha

Summary: This literature review discusses the extraction of phenolic compounds using green deep eutectic solvents, including their composition, factors affecting extraction, and extraction conditions.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

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Review Plant Sciences

The traditional uses, phytochemistry, and pharmacological properties of Paris L. (Liliaceae): A review

Yu-Gang Ding et al.

Summary: Genus Paris, mainly distributed in Southwest China, has over 320 chemical components isolated, showing a wide range of pharmacological effects such as antitumor, cytotoxic, antimicrobial, hemostatic, and anti-inflammatory activities. The rhizomes of Paris species are traditionally used in folk medicine to treat wounds, bleeding, and stomachache.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

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Article Chemistry, Applied

Sonication-synergistic natural deep eutectic solvent as a green and efficient approach for extraction of phenolic compounds from peels of Carya cathayensis Sarg

Xizhe Fu et al.

Summary: Combining natural deep eutectic solvent with pulse-ultrasonication technique demonstrated significant synergistic effect and high efficiency in extracting phenolic compounds from Carya cathayensis Sarg. peels. The development and validation of a second-order kinetic model further confirmed the synergistic effect and influence during extraction.

FOOD CHEMISTRY (2021)

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Article Agricultural Engineering

Sustainable ultrasound-assisted extraction of valuable phenolics from inflorescences of Helichrysum arenarium L. using natural deep eutectic solvents

Milena Ivanovic et al.

Summary: The study demonstrates an environmentally friendly analytical method using NADESs and UAE to extract valuable phenolic compounds from Helichrysum arenarium L. The optimized conditions obtained promising extraction efficiencies, showcasing potential for clean production with minimal environmental impact.

INDUSTRIAL CROPS AND PRODUCTS (2021)

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Article Plant Sciences

Ecdysteroids and spirosterane steroids from the traditional Chinese medicine Paris polyphylla var. yunnanensis

Kai Guo et al.

Summary: The phytochemical investigation of Paris polyphylla var. yunnanensis rhizomes resulted in the isolation of four ecdysteroids, including two new ones, and two known spirostane steroids. The structures were identified through spectroscopic analyses and comparisons with existing literature. All isolates were tested for their immunosuppressive and adipogenesis inhibitory activities, but were found to be inactive.

PHYTOCHEMISTRY LETTERS (2021)

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Article Engineering, Chemical

Ultrasound-assisted pressurized liquid extraction of anthocyanins from Aronia melanocarpa pomace

Thalles Allan Andrade et al.

Summary: This study aimed to investigate the optimum conditions for ultrasonic-assisted pressurized liquid extraction of anthocyanins from Aronia melanocarpa pomace. Through optimization of pressure, temperature, ultrasound intensity, and solvent concentration, the total anthocyanin content extracted was increased by 19% at 80 degrees Celsius.

SEPARATION AND PURIFICATION TECHNOLOGY (2021)

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Article Acoustics

Effects of ultrasound-assisted basic electrolyzed water (BEW) extraction on structural and functional properties of Antarctic krill (Euphausia superba) proteins

Yufeng Li et al.

Summary: The novel protein extraction method using ultrasound-assisted basic electrolyzed water (BEW) improved the efficiency and functional properties of Antarctic krill proteins, leading to enhancements in foam capacity, foam stability, and emulsifying capacity. Overall, ultrasound-assisted BEW shows potential as an alternative method for extracting high-quality marine proteins.

ULTRASONICS SONOCHEMISTRY (2021)

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Review Chemistry, Analytical

Advances in ionic liquids and deep eutectic solvents-based liquid phase microextraction of metals for sample preparation in Environmental Analytical Chemistry

Belen Herce-Sesa et al.

Summary: The incorporation of ionic liquids in LPME for metal extraction has shown great potential in sample preparation for environmental analysis. This has led to the development of more efficient and selective extraction methods, with the use of task specific ionic liquids and deep eutectic solvents. The future development of IL-LPME for metal extraction shows promise for further advancements in the field.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2021)

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Review Chemistry, Multidisciplinary

Basics and properties of deep eutectic solvents: a review

Tracy El Achkar et al.

Summary: Deep eutectic solvents, emerging in green chemistry only seventeen years ago, have led to a plethora of publications covering various research areas and diverse fields of application. They are seen as promising alternatives to conventional organic solvents due to their straightforward preparation using highly accessible and natural compounds, as well as high tunability in properties. The physicochemical properties of these solvents, such as phase behavior, density, viscosity, ionic conductivity, surface tension, and polarity, can be controlled by factors like the choice of forming compounds, molar ratio, temperature, and water content.

ENVIRONMENTAL CHEMISTRY LETTERS (2021)

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Article Chemistry, Applied

One-pot method based on deep eutectic solvent for extraction and conversion of polydatin to resveratrol from Polygonum cuspidatum

Bo Sun et al.

Summary: A novel one-pot method based on deep eutectic solvent (DES) was developed to efficiently extract and convert polydatin to resveratrol from Polygonum cuspidatum. The extraction yield of resveratrol using DES was significantly higher than traditional solvents. The DES disrupted plant cell walls to enhance resveratrol yield.

FOOD CHEMISTRY (2021)

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Article Agricultural Engineering

Ultrasound-assisted extraction of five anthraquinones from Rheum palmatum water extract residues and the antimicrobial activities

Li-Xia Dai et al.

Summary: This study successfully enriched five anthraquinones from Rheum palmatum water extract residues using ultrasound-assisted extraction method, with rhein showing strong antifungal activity against Botrytis cinerea.

INDUSTRIAL CROPS AND PRODUCTS (2021)

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Article Biochemistry & Molecular Biology

Natural Deep Eutectic Solvents for the Extraction of Bioactive Steroidal Saponins from Dioscoreae Nipponicae Rhizoma

Gui-Ya Yang et al.

Summary: A simple and environmentally friendly extraction method using natural deep eutectic solvents (NADESs) was established to extract four bioactive steroidal saponins from Dioscoreae Nipponicae Rhizoma (DNR). The optimized extraction parameters were determined, and the steroidal saponins were successfully recovered using D101 macroporous resin. This study highlights the potential of NADESs as green media for efficiently extracting bioactive compounds from natural products.

MOLECULES (2021)

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Article Plant Sciences

Effects of Yunanan Baiyao adjunct therapy on postoperative recovery and clinical prognosis of patients with traumatic brain injury: A randomized controlled trial

Lifeng Chen et al.

Summary: Adjunct therapies with YB and XNJ can improve postoperative recovery and clinical prognosis in patients with moderate-to-severe TBI, possibly through divergent regulation of S100B and SOD pathways.

PHYTOMEDICINE (2021)

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Article Agricultural Engineering

Gibberellin A3 induces polyaerial shoot formation and increases the propagation rate in Paris polyphylla rhizomes

Mulan Wang et al.

Summary: The study found that Paris polyphylla rhizomes mainly sprout one shoot, but occasionally multiple apical shoots can develop. Application of GA3 can break dormancy within two weeks and stimulate the growth of polyapical shoots at a rate of 100%. These results suggest that GA3 treatment can efficiently induce the formation of polyapical shoots in P. polyphylla, providing a promising propagation technique.

INDUSTRIAL CROPS AND PRODUCTS (2021)

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Article Acoustics

Comparison of the effect of extraction methods on the quality of green coffee oil from Arabica coffee beans: Lipid yield, fatty acid composition, bioactive components, and antioxidant activity

Wenjiang Dong et al.

Summary: This study compared the extraction efficiency of four methods for extracting green coffee oil, as well as the impact on fatty acids, tocopherols, diterpenes, and total phenols in the oil. The results showed significant differences in these components among the different extraction methods, with GCO exhibiting high antioxidant activity.

ULTRASONICS SONOCHEMISTRY (2021)

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Review Chemistry, Multidisciplinary

Recent Advances in Ionic Liquids in Biomedicine

Alexander M. Curreri et al.

Summary: Ionic liquids and deep eutectic solvents have seen a significant growth in biomedical applications, particularly in drug solubilization, formulation, delivery, protein stabilization, and new biosensors. Overcoming current challenges in these applications will require considerations of biocompatibility, impurities, and a comprehensive understanding of microscopic interactions within ionic liquids.

ADVANCED SCIENCE (2021)

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Review Biotechnology & Applied Microbiology

Genetic Diversity, Chemical Components, and Property of Biomass Paris polyphylla var. yunnanensis

Nong Zhou et al.

Summary: This review article discusses the genetic diversity, chemical components, and the influence of arbuscular mycorrhizal fungi on Paris polyphylla var. yunnanensis biomass resources. It highlights the potential value of utilizing this biomass resource in the biomedical field.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

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Review Chemistry, Analytical