Fertility Outcomes after Surgical Management of Colorectal Endometriosis: A Single-center Retrospective Study

Study Objective: To assess the pregnancy rate after surgery for colorectal endometriosis.Design: A retrospective, single-center study performed from January 2014 to December 2019.Setting: A university tertiary referral center.Patients: Patients with the intention to get pregnant younger than the age of 43 years, with or without a history of infertility and who were surgically managed for colorectal endometriosis.Interventions: Complete excision of deeply infiltrating endometriosis. Measurements and Main Results: The postoperative pregnancy rate was assessed. Seventy-seven patients had surgery; their mean age was 32.5 +/- 4.4 years. Preoperative documented infertility was present in 77.9% of patients (n = 60). The mean length of history of infertility was 36.2 +/- 24.9 months. The procedure was performed by laparoscopic surgery in 92.2% of patients (n = 71). Nonconservative, conservative, and mixed treatment were performed in 66.2% (n = 51), 29.9% (n = 23), and 3.9% of patients (n = 3), respectively. According to the Clavien-Dindo classification, the 3B complication rate was 6.5% (n = 5). The mean follow-up was 46.7 +/- 20.6 months. Clinical pregnancies were defined by the presence of intra-uterine pregnancy with an embryo with cardiac activity. The postoperative pregnancy rate was 62.3% (n = 48), and 54.2% (n = 26) were spontaneous. The mean number of pregnancies was 1.2 +/- 0.4 per patient. In addition, 18.7% of patients (n = 9) got pregnant twice. The mean time from surgery to pregnancy was 13.8 +/- 13.1 months. The live birth rate was 89.1% (n = 41). There were no significant differences concerning the prognostic criteria reported in the literature (anti-mueurollerian hormone level, age, presence of adenomyosis). There were no predictive criteria for live births.Conclusion: According to this study, surgery for colorectal endometriosis results in a high postoperative pregnancy rate. Studies with a high level of evidence are needed to determine good candidates for this type of surgery. Journal of Minimally Invasive Gynecology (2023) 30, 230-239. (c) 2022 AAGL. All rights reserved.

Automated summary

This study aimed to assess the pregnancy rate after surgery for colorectal endometriosis. The results showed a high postoperative pregnancy rate for patients with colorectal endometriosis, and further studies with a high level of evidence are needed to determine good candidates for this type of surgery.