相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicans
Chaochen Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Novel Carboline Fungal Histone Deacetylase (HDAC) Inhibitors for Combinational Treatment of Azole-Resistant Candidiasis
Zhuang Li et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Lanosterol 14α-demethylase (CYP51)/histone deacetylase (HDAC) dual inhibitors for treatment of Candida tropicalis and Cryptococcus neoformans infections
Tianbao Zhu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads
Linda Schaeker-Huebner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Fungal Lysine Deacetylases in Virulence, Resistance, and Production of Small Bioactive Compounds
Ingo Bauer et al.
GENES (2021)
Potent Dual BET/HDAC Inhibitors for Efficient Treatment of Pancreatic Cancer
Shipeng He et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Discovery of Thieno[2,3-d]pyrimidine-Based Hydroxamic Acid Derivatives as Bromodomain-Containing Protein 4/Histone Deacetylase Dual Inhibitors Induce Autophagic Cell Death in Colorectal Carcinoma Cells
Zhaoping Pan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Discovery of Novel Fungal Lanosterol 14α-Demethylase (CYP51)/Histone Deacetylase Dual Inhibitors to Treat Azole-Resistant Candidiasis
Guiyan Han et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight
Terence C. S. Ho et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Multidrug transporters of Candida species in clinical azole resistance
Rajendra Prasad et al.
FUNGAL GENETICS AND BIOLOGY (2019)
Systemic infection with Candida albicans in breast tumor bearing mice: Cytokines dysregulation and induction of regulatory T cells
N. Ahmadi et al.
JOURNAL DE MYCOLOGIE MEDICALE (2019)
Straightforward hit identification approach in fragment-based discovery of bromodomain-containing protein 4 (BRD4) inhibitors
Petro Borysko et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Discovery of Janus Kinase 2 (JAK2) and Histone Deacetylase (HDAC) Dual Inhibitors as a Novel Strategy for the Combinational Treatment of Leukemia and Invasive Fungal Infections
Yahui Huang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor
Yujun Zhao et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Panobinostat andMultipleMyeloma in 2018
Andrew J. Yee et al.
ONCOLOGIST (2018)
Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor
Yujun Zhao et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Drug Discovery Targeting Bromodomain-Containing Protein 4
Zhiqing Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor
Keith F. McDaniel et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
The Search for Potent, Small-Molecule HDACIs in Cancer Treatment: A Decade After Vorinostat
Chiara Zagni et al.
MEDICINAL RESEARCH REVIEWS (2017)
The antifungal pipeline: a reality check
John R. Perfect
NATURE REVIEWS DRUG DISCOVERY (2017)
Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation
Jesus A. Romo et al.
MBIO (2017)
Selective BET bromodomain inhibition as an antifungal therapeutic strategy
Flore Mietton et al.
NATURE COMMUNICATIONS (2017)
Structure-based design, synthesis and in vitro antiproliferative effects studies of novel dual BRD4/HDAC inhibitors
Mingfeng Shao et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Synthesis and evaluation of novel dual BRD4/HDAC inhibitors
Seika Amemiya et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Inhibitors of histone deacetylase as antitumor agents: A critical review
Mohammed Manal et al.
BIOORGANIC CHEMISTRY (2016)
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
Shaokun Shu et al.
NATURE (2016)
Histone Deacetylases and Their Inhibition in Candida Species
Cecile Garnaud et al.
FRONTIERS IN MICROBIOLOGY (2016)
How Chemotherapy Increases the Risk of Systemic Candidiasis in Cancer Patients: Current Paradigm and Future Directions
Flora Teoh et al.
PATHOGENS (2016)
Antifungal Drugs: The Current Armamentarium and Development of New Agents
Nicole Robbins et al.
MICROBIOLOGY SPECTRUM (2016)
Histone deacetylase-mediated morphological transition in Candida albicans
Jueun Kim et al.
JOURNAL OF MICROBIOLOGY (2015)
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition
Philipp Rathert et al.
NATURE (2015)
Histone deacetylases: targets for antifungal drug development
Livia Kmetzsch
VIRULENCE (2015)
Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762
Aristeidis Chaidos et al.
BLOOD (2014)
Targeting bromodomains: epigenetic readers of lysine acetylation
Panagis Filippakopoulos et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Novel Carboline Derivatives as Potent Antifungal Lead Compounds: Design, Synthesis, and Biological Evaluation
Shengzheng Wang et al.
ACS MEDICINAL CHEMISTRY LETTERS (2014)
Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates
Christopher J. Millard et al.
MOLECULAR CELL (2013)
Candida albicans morphogenesis and host defence: discriminating invasion from colonization
Neil A. R. Gow et al.
NATURE REVIEWS MICROBIOLOGY (2012)
Multilaboratory Testing of Two-Drug Combinations of Antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis
Vishnu Chaturvedi et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
Mark A. Dawson et al.
NATURE (2011)
Selective inhibition of BET bromodomains
Panagis Filippakopoulos et al.
NATURE (2010)
Chemical phylogenetics of histone deacetylases
James E. Bradner et al.
NATURE CHEMICAL BIOLOGY (2010)
A comparative histopathological study of systemic candidiasis in association with experimentally induced breast cancer
Z. W. Choo et al.
ONCOLOGY LETTERS (2010)
Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens
M. A. Pfaller et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2009)
In vitro interactions of anidulafungin with azole antifungals, amphotericin B and 5-fluorocytosine against Candida species
JA Karlowsky et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2006)
Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals:: Correlation with reduction in CDR and ERG upregulation
WL Smith et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
分享论文
