A Review of State-of-the-Art on Enabling Additive Manufacturing Processes for Precision Medicine

Article Engineering, Manufacturing

Volumetric 3D printing for rapid production of medicines

Lucia Rodriguez-Pombo et al.

Summary: 3D printing has potential in personalized medicine era, volumetric printing allows rapid drug printing with advantages in speed and overcoming limitations, drug release rates can be controlled by adjusting resin composition ratios.

ADDITIVE MANUFACTURING (2022)

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Review Pharmacology & Pharmacy

Innovations in Chewable Formulations: The Novelty and Applications of 3D Printing in Drug Product Design

Lucia Rodriguez-Pombo et al.

Summary: Chewable dosage forms have gained popularity in medical field due to their ease of swallowing. However, current formulations lack individualized dosing and palatability preferences. Three-dimensional printing has emerged as a novel manufacturing method to produce customized chewable dosage forms.

PHARMACEUTICS (2022)

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Article Pharmacology & Pharmacy

3D printed tacrolimus suppositories for the treatment of ulcerative colitis

Iria Seoane-Viano et al.

Summary: This study presents the fabrication of self-supporting tacrolimus suppositories using 3D printing technology, offering potential benefits for patients with ulcerative colitis. Although the two suppository formulations showed differences in drug release rate and disintegration, both released over 80% of the drug within 120 minutes.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

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Article Pharmacology & Pharmacy

Preparation and characterization of hot-melt extruded polycaprolactone-based filaments intended for 3D-printing of tablets

Laura Viidik et al.

Summary: Hot-melt extruded (HME) filaments are essential for 3D printing drug delivery systems (DDS) using fused deposition modelling (FDM). This study designed novel polymeric HME filaments loaded with active pharmaceutical ingredients (APIs), and investigated their physical properties, mechanical properties, drug release, and short-term stability. The combination of polycaprolactone (PCL) and arabic gum (ARA) showed promise as a carrier system for 3D-printable HME filaments and tablets, with sustained drug release observed in vitro.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

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Article Pharmacology & Pharmacy

Haptic Evaluation of 3D-printed Braille-encoded Intraoral Films

Georgios K. Eleftheriadis et al.

Summary: The application of 3D printing technology in the pharmaceutical field not only enables personalized dosing and formulation designs, but also allows for the direct imprinting of haptic identifiers on drug surfaces, catering to specific populations such as visually impaired individuals. Research shows that using fused deposition modelling (FDM) technique to manufacture intraoral films with Braille characters can provide novel design concepts for drug delivery, demonstrating the potential of FDM technology in combining individualized therapies and customized services for specific populations.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

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Article Chemistry, Medicinal

A Wirelessly Controlled Scalable 3D-Printed Microsystem for Drug Delivery

Farzad Forouzandeh et al.

Summary: A 3D-printed microsystem for drug delivery, including a refillable microreservoir and a phase-change peristaltic micropump, was optimized for murine inner ear drug delivery and demonstrated favorable results in long-term subcutaneous implantation experiments. Real-time monitoring during drug infusion showed similar results with syringe pump infusion, indicating the scalability of this low-cost design and fabrication methodology for different clinical applications and delivery sites.

PHARMACEUTICALS (2021)

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Article Pharmacology & Pharmacy

Quality considerations on the pharmaceutical applications of fused deposition modeling 3D printing

Alice Melocchi et al.

Summary: 3D printing technology, particularly FDM, has rapidly become a hot topic in pharmaceutical research and media attention, with significant growth expected in 2020. Further development of FDM 2.0 process is needed to ensure the production of safe, high-quality personalized drug products.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Review Chemistry, Multidisciplinary

Vat photopolymerization 3D printing for advanced drug delivery and medical device applications

Xiaoyan Xu et al.

Summary: Vat photo-polymerization 3D printing technology offers high resolution and fast printing speeds, making it ideal for creating custom medical devices and drug delivery systems. Its adoption is expected to advance personalized healthcare systems.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Materials Science, Biomaterials

Anti-biofilm multi drug-loaded 3D printed hearing aids

Maria Vivero-Lopez et al.

Summary: Over 5% of the world's population has disabling hearing loss, affecting approximately one third of individuals over 65 years. Hearing aids loaded with antibiotics have been successfully 3D printed, showing antibacterial properties and sustained drug release. This highlights the potential of vat photopolymerization 3D printing for manufacturing medical devices with anti-bacterial properties.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

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Article Orthopedics

Design and development of a novel 3D-printed non-metallic self-locking prosthetic arm for a forequarter amputation

Trevor Binedell et al.

Summary: This study aimed to design and develop a 3D-printed cosmetic forequarter prosthesis that is fully customized, lightweight, cool to wear, and matches the user's appearance needs. By using an iterative user-centered design approach, the final cost was 20% cheaper than traditional forequarter prostheses and received high user satisfaction.

PROSTHETICS AND ORTHOTICS INTERNATIONAL (2021)

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Review Pharmacology & Pharmacy

Pharmaceutical applications of powder-based binder jet 3D printing process - A review

Koyel Sen et al.

Summary: Pharmaceutical applications of 3D printing have matured with FDA approval of Spritam, the first commercial 3D printed dosage form, but there is still a lack of understanding regarding the effect of raw materials on printed dosage forms and the feasibility of using this technology beyond conventional methods.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Review Pharmacology & Pharmacy

Electrochemical biosensors: a nexus for precision medicine

Thomas D. Pollard et al.

Summary: Precision medicine has great potential for improving patient quality of life through therapeutic drug monitoring (TDM), with electrochemical biosensors (ECBs) offering a cost-effective, portable, and highly sensitive solution to current TDM challenges. Emerging strategies for continuous drug monitoring are being explored to enhance the field's developments and outlook.

DRUG DISCOVERY TODAY (2021)

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Article Computer Science, Interdisciplinary Applications

Artificial intelligence based design of 3D-printed tablets for personalise d me dicine

Zdenek Grof et al.

Summary: A computational method based on an Evolutionary Algorithm is introduced to find tablet internal structures that result in prescribed dissolution profiles of each API. The algorithm has been tested on known solutions and successfully applied to finding tablet structures that result in delayed release and step-wise release profiles. This approach, combined with patient-specific requirements, can be used for automated design of 3D-printed tablets in the framework of personalized medicine.

COMPUTERS & CHEMICAL ENGINEERING (2021)

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Article Pharmacology & Pharmacy

Paracetamol extended release FDM 3D printlets: Evaluation of formulation variables on printability and drug release

Marija Duranovic et al.

Summary: Paracetamol printlets were prepared using hot-melt extrusion process and fused deposition modelling with PCL and PEO backbone polymers. The study showed that the backbone polymer plays a crucial role in obtaining printlets with desired properties. PEO-based filaments were more prone to clogging in the printcore, but exhibited faster drug release.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

Oral preparations with tunable dissolution behavior based on selective laser sintering technique

Yan Yang et al.

Summary: Selective laser sintering (SLS) is used to prepare 3D printlets for tissue engineering and personalized implants. The printability of oral solid preparations was evaluated using a low energy laser, finding that yellow drugs and tartrazine lake can enhance printability. Increasing laser energy density improves printing efficiency but reduces accuracy, with different drugs having different printing mechanisms.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Review Pharmacology & Pharmacy

Recent progress of 3D-printed microneedles for transdermal drug delivery

Qingliang Yang et al.

Summary: Microneedles as a novel transdermal drug delivery system have gained extensive attention for their improved patient compliance and self-administration compared to traditional administration methods. Recent studies on utilizing 3D printing to fabricate transdermal drug delivery systems show promising potential for versatile printing methodologies and different formulation strategies.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

3D printed bilayer tablet with dual controlled drug release for tuberculosis treatment

Atabak Ghanizadeh Tabriz et al.

Summary: This study utilized Fusion Deposition Modelling (FDM) to design and fabricate a bilayer tablet for tuberculosis treatment, with one drug releasing in the stomach and another in the upper intestine. The bilayer tablet preparation involved hot melt extrusion and 3D printing, optimizing drug release and ensuring consistent drug-containing layers. The study demonstrated the potential application of FDM technology in developing personalized clinical treatment options for oral fixed-dose combinations.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

3D printed estradiol-eluting urogynecological mesh implants: Influence of material and mesh geometry on their mechanical properties

Zara-Louise Farmer et al.

Summary: This study investigated the use of thermoplastic polyurethane (TPU) as an alternative material for surgical mesh implants instead of polypropylene (PP), and hormone-loaded meshes were produced using fused deposition modelling. The results showed that TPU meshes were more suitable for pelvic floor repair than PP, and 3D printed meshes exhibited linear release of 17-beta-estradiol (E2) over a two weeks period.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Materials Science, Biomaterials

Stereolithography (SLA) 3D printing of a bladder device for intravesical drug delivery

Xiaoyan Xu et al.

Summary: This study introduces the use of stereolithography (SLA) 3D printing for manufacturing novel indwelling bladder devices that allow extended and localized delivery of lidocaine hydrochloride. The devices showed good blood compatibility, resistance to external forces, and sustained drug release capabilities. This new approach offers potential for personalized and revolutionary intravesical drug delivery for bladder diseases.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

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Article Biochemistry & Molecular Biology

Tailoring Atomoxetine Release Rate from DLP 3D-Printed Tablets Using Artificial Neural Networks: Influence of Tablet Thickness and Drug Loading

Gordana Stanojevic et al.

Summary: Various 3DP technologies have been investigated for producing customizable medicines and medical devices, with this study focusing on tailoring drug release rates from DLP 3D-printed tablets. By varying tablet thickness and drug loading, a series of tablets with different doses and release profiles were successfully fabricated, demonstrating the technology's potential for on-demand manufacturing of dosage forms.

MOLECULES (2021)

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Article Pharmacology & Pharmacy

Smartphone-enabled 3D printing of medicines

Xiaoyan Xu et al.

Summary: 3D printing technology is being widely used in personalized pharmaceuticals, and portable, easy-to-operate printers are needed to realize the potential of point-of-care manufacturing of personalized medications.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Review Chemistry, Multidisciplinary

From Diagnosis to Treatment: Recent Advances in Patient-Friendly Biosensors and Implantable Devices

Pei Li et al.

Summary: Patient-friendly medical diagnostics and treatments have gained significant attention for their rapid development of portable biosensors and implantable devices. Challenges related to wearable biosensors are highlighted, along with advances in implantable devices and patient-friendly surgical approaches.

ACS NANO (2021)

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Article Pharmacology & Pharmacy

3D-printing of solid lipid tablets from emulsion gels

Jenny Johannesson et al.

Summary: This study demonstrated the successful fabrication of solid lipid tablets containing poorly water-soluble drug using semi-solid extrusion printing, with advantages including rapid disintegration and consistency in oil droplet size after dispersion.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

3D printing of gummy drug formulations composed of gelatin and an HPMC-based hydrogel for pediatric use

Tatsuaki Tagami et al.

Summary: The study used a 3D bioprinter to fabricate gummy drug formulations for pediatric patients, incorporating gelatin, HPMC, and other materials. The strength of the gummy formulations was significantly influenced by the concentration of gelatin, and dissolution tests showed 85% drug release within 15 minutes from most formulations.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Engineering, Manufacturing

An Experimental and Numerical Study on Coaxial Extrusion of a Non-Newtonian Hydrogel Material

Ilhan Yu et al.

Summary: This study investigates the stability of coaxial extrusion of a non-Newtonian material, Pluronic F127, and finds that viscosity ratio, flowrate ratio, and non-Newtonian behaviors can affect the stability of the process. The study highlights the interconnected relationship between viscosity, flowrate, and non-Newtonian fluid behaviors and provides guidance on how to alter extrusion parameters to achieve the desired flow pattern.

JOURNAL OF MANUFACTURING SCIENCE AND ENGINEERING-TRANSACTIONS OF THE ASME (2021)

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Review Pharmacology & Pharmacy

Opportunities and challenges of three-dimensional printing technology in pharmaceutical formulation development

Mengsuo Cui et al.

Summary: Three-dimensional printing technology prints products layer by layer, offering competitive advantages in product design complexity, personalization, and on-demand manufacturing. This technology shows innovative potential in drug delivery systems, while also facing limitations and challenges in pharmaceutical formulation development.

ACTA PHARMACEUTICA SINICA B (2021)

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Review Pharmacology & Pharmacy

3DP Printing of Oral Solid Formulations: A Systematic Review

Chiara R. M. Brambilla et al.

Summary: Three-dimensional (3D) printing technology allows for the manufacturing of personalized dosage forms, with applications such as oral solid dosage forms. Different 3DP techniques, such as FDM, inkjet 3DP, SLA, and SLS, have been used for manufacturing oral solid formulations and each technique has its own advantages and disadvantages. The selection of the most suitable technique depends on various factors, including the type of formulation and desired physical-mechanical properties.

PHARMACEUTICS (2021)

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Review Pharmacology & Pharmacy

Harnessing artificial intelligence for the next generation of 3D printed medicines

Moe Elbadawi et al.

Summary: Artificial intelligence is reshaping various sectors, but its potential in the pharmaceutical industry has yet to be fully tapped. The integration of AI and 3D printing technology offers opportunities for personalized medicine production and streamlined processes. Leveraging AI in pharmaceutical 3DP can enhance efficiency and drive the development of personalized medicine.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Article Biophysics

Optical biosensors-Illuminating the path to personalized drug dosing

Jun Jie Ong et al.

Summary: Optical biosensors are poised to revolutionize the medical industry, with successful applications in health monitoring and potential benefits in drug detection and monitoring. Personalized dosing using optical biosensors has the ability to significantly improve patient lives.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Pharmacology & Pharmacy

Customizable drug tablets with constant release profiles via 3D printing technology

Yan Jie Neriah Tan et al.

Summary: Medicine should be personalized based on individual differences, and can be achieved by using 3D printing to customize drug tablets with specific dosages, release durations, and combinations of drugs. The method involves printing a template and fabricating the drug tablet according to the template, allowing for customizable tablets with a simple structure and efficient constant release profile.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Review Chemistry, Multidisciplinary

Semi-solid extrusion 3D printing in drug delivery and biomedicine: Personalised solutions for healthcare challenges

Iria Seoane-Viano et al.

Summary: SSE 3D printing is a low-temperature printing technology suitable for drug delivery and biomedical applications, creating objects of any size and shape by sequentially depositing layers of gel or paste.

JOURNAL OF CONTROLLED RELEASE (2021)

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Review Pharmacology & Pharmacy

Connected healthcare: Improving patient care using digital health technologies

Atheer Awad et al.

Summary: Digital technologies of Healthcare 4.0 are revolutionizing traditional healthcare models, with advancements in patient monitoring, personalized medicine, precision surgery, and medical logistics using drones. This review discusses the most promising healthcare technologies, their strengths, limitations, and opportunities for clinical adoption.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Review Pharmacology & Pharmacy

Advances in powder bed fusion 3D printing in drug delivery and healthcare

Atheer Awad et al.

Summary: Powder bed fusion (PBF) is a 3D printing method that selectively consolidates powders into 3D objects using a power source. PBF technologies offer benefits such as superior printing resolution and speed, as well as the ability to create complex products without the need for secondary supports, making them well suited for bespoke drug-laden formulations, devices, and implants.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Review Pharmacology & Pharmacy

Polymeric drug delivery systems by additive manufacturing

Sedigheh Borandeh et al.

Summary: This review provides a comprehensive overview on recent developments in polymeric drug delivery systems prepared by additive manufacturing, discussing the materials, properties, design and fabrication techniques, and mechanisms used for achieving controlled release systems. The current challenges and future perspectives for personalized medicine and clinical use are briefly discussed.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Article Pharmacology & Pharmacy

Industry 4.0 for pharmaceutical manufacturing: Preparing for the smart factories of the future

N. Sarah Arden et al.

Summary: Over the past two centuries, medicines have evolved from crude herbal preparations to sophisticated drug products, with pharmaceutical manufacturing technologies continuing to advance. The application of modern technologies like IoT, AI, robotics and advanced computing is expected to enhance the agility, efficiency, flexibility, and quality of industrial production of medicines, shaping the future of pharmaceutical manufacturing. Vision and understanding of regulatory, technical, and logistical barriers are essential for realizing the benefits of these technologies.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Chemistry, Multidisciplinary

Machine learning predicts 3D printing performance of over 900 drug delivery systems

Brais Muniz Castro et al.

Summary: Three-dimensional printing (3DP) is a transformative technology in pharmaceutical research, producing personalized drug products. However, slow progress has been made due to the lengthy trial-and-error optimization process. Artificial intelligence (AI) has the potential to revolutionize pharmaceutical 3DP by analyzing large datasets.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Chemistry, Analytical

Fully Integrated 3D-Printed Electronic Device for the On-Field Determination of Antipsychotic Drug Quetiapine

Katerina Ragazou et al.

Summary: In this study, a novel all-3D-printed device for the determination of quetiapine fumarate (QF) via voltammetric mode was developed. The device features optimized electrochemical parameters, requires no post-treatment before use, and exhibits high sensitivity and reproducibility in testing.

SENSORS (2021)

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Review Pharmacology & Pharmacy

Disrupting 3D printing of medicines with machine learning

Moe Elbadawi et al.

Summary: 3D printing technology has the potential to revolutionize pharmaceutical development, but its integration into clinical settings can be accelerated by partnering with modern technologies like machine learning. This collaboration can expedite drug product development and inspire innovative dosage-form design, marking the next era of personalized medicine.

TRENDS IN PHARMACOLOGICAL SCIENCES (2021)

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Article Engineering, Biomedical

Design and Usability Evaluations of a 3D-Printed Implantable Drug Delivery Device for Acute Liver Failure in Preclinical Settings

Shin-Young Kim et al.

Summary: This study evaluates the in vivo safety and usability of a 3D-printed implantable drug delivery device for ALF treatment. The results show that the device is safe for use and can deliver various active pharmaceutical ingredients to the liver tissue for the treatment of acute liver failure.

ADVANCED HEALTHCARE MATERIALS (2021)

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Article Pharmacology & Pharmacy

Machine Learning Uncovers Adverse Drug Effects on Intestinal Bacteria

Laura E. McCoubrey et al.

Summary: The human gut microbiome plays a crucial role in human health, and drugs can have significant effects on it. This study utilizes a machine learning model to predict the impact of drugs on the growth of 40 gut bacterial strains, offering a new tool for the pharmaceutical industry and clinical settings.

PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

Personalised Tasted Masked Chewable 3D Printed Fruit-Chews for Paediatric Patients

Atabak Ghanizadeh Tabriz et al.

Summary: The study focused on the development of personalised paediatric dosage forms using 3D printing technologies, specifically creating fruit-chew designs with strawberry flavor that effectively masked the bitterness and enhanced taste perception. This approach showed potential for improving medication adherence in children through enhanced organoleptic properties.

PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

Direct Powder Extrusion 3D Printing of Praziquantel to Overcome Neglected Disease Formulation Challenges in Paediatric Populations

Janine Boniatti et al.

Summary: This study demonstrates the successful preparation of pediatric Printlets(TM) of praziquantel using DPE 3DP technology, addressing the lack of suitable pediatric formulations for schistosomiasis treatment. The technology showed excellent taste masking capabilities and significantly increased praziquantel release, potentially overcoming the main formulation hurdles of the drug.

PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

3D Printed Punctal Plugs for Controlled Ocular Drug Delivery

Xiaoyan Xu et al.

Summary: This study successfully developed dexamethasone-loaded punctal plugs using digital light processing (DLP) 3D printing, achieving sustained release for up to 21 days, providing a new solution for ocular treatment.

PHARMACEUTICS (2021)

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Article Materials Science, Multidisciplinary

Combining 3D printing and screen-printing in miniaturized, disposable sensors with carbon paste electrodes

Elsa Maria Materon et al.

Summary: This paper presents a modular design that combines 3D printing and screen printing to fabricate electrochemical sensors, showcasing the detection of drugs and biomarkers with high sensitivity and rapid response. The design allows for customization with various nanomaterials and biomolecules, offering potential for clinical applications.

JOURNAL OF MATERIALS CHEMISTRY C (2021)

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Review Gastroenterology & Hepatology

Harnessing machine learning for development of microbiome therapeutics

Laura E. McCoubrey et al.

Summary: Seminal microbiome research in the past twenty years has shown the intrinsic relationship between microbiota and human health, with imbalanced microbiomes linked to diseases. Machine learning offers powerful techniques for analyzing and predicting microbiome big data, facilitating the development of new therapeutics.

GUT MICROBES (2021)

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Article Chemistry, Multidisciplinary

Recent Advances in Enabling Technologies in 3D Printing for Precision Medicine

Margaret E. Prendergast et al.

ADVANCED MATERIALS (2020)

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Review Biotechnology & Applied Microbiology

Engineering inkjet bioprinting processes toward translational therapies

Ioannis Angelopoulos et al.

BIOTECHNOLOGY AND BIOENGINEERING (2020)

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Article Materials Science, Paper & Wood

Three-dimensional (3D) printed tablets using ethyl cellulose and hydroxypropyl cellulose to achieve zero order sustained release profile

Shiva Homaee Borujeni et al.

CELLULOSE (2020)

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Article Biotechnology & Applied Microbiology

A laser-engraved wearable sensor for sensitive detection of uric acid and tyrosine in sweat

Yiran Yang et al.

NATURE BIOTECHNOLOGY (2020)

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Article Pharmacology & Pharmacy

Preparation and characterization of indomethacin loaded films by piezoelectric inkjet printing: a personalized medication approach

Muhammad Sohail Arshad et al.

PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2020)

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Article Pharmacology & Pharmacy

Fabrication of an osmotic 3D printed solid dosage form for controlled release of active pharmaceutical ingredients

Christos Gioumouxouzis et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

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Article Pharmacology & Pharmacy

Paediatric-friendly chocolate-based dosage forms for the oral administration of both hydrophilic and lipophilic drugs fabricated with extrusion-based 3D printing

Christina Karavasili et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

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Article Pharmacology & Pharmacy

3D printing of multilayered orodispersible films with in-process drying

Jan Elbl et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Simplification of fused deposition modeling 3D-printing paradigm: Feasibility of 1-step direct powder printing for immediate release dosage form production

Marina Fanous et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Non-destructive dose verification of two drugs within 3D printed polyprintlets

Sarah J. Trenfield et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients

Atheer Awad et al.

PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Selective Laser Sintering 3D Printing of Orally Disintegrating Printlets Containing Ondansetron

Nour Allahham et al.

PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Printability of External and Internal Structures Based on Digital Light Processing 3D Printing Technique

Yan Yang et al.

PHARMACEUTICS (2020)

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Review Pharmacology & Pharmacy

Polymers for Extrusion-Based 3D Printing of Pharmaceuticals: A Holistic Materials-Process Perspective

Mohammad A. Azad et al.

PHARMACEUTICS (2020)

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Article Engineering, Manufacturing

Integrated laser-based powder bed fusion and fused filament fabrication for three-dimensional printing of hybrid metal/polymer objects

Yuan-Hui Chueh et al.

ADDITIVE MANUFACTURING (2020)

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Article Polymer Science

Development and Optimisation of Novel Polymeric Compositions for Sustained Release Theophylline Caplets (PrintCap) via FDM 3D Printing

Deck Khong Tan et al.

POLYMERS (2020)

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Article Pharmacology & Pharmacy

Investigation of semi-solid formulations for 3D printing of drugs after prolonged storage to mimic real-life applications

Ilias El Aita et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

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Article Pharmacology & Pharmacy

3D printed opioid medicines with alcohol-resistant and abuse-deterrent properties

Jun Jie Ong et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Engineering, Manufacturing

Controllability Over Wall Thickness of Tubular Structures and Encapsulation During Co-Axial Extrusion of a Thermal- Crosslinking Hydrogel

Ilhan Yu et al.

JOURNAL OF MANUFACTURING SCIENCE AND ENGINEERING-TRANSACTIONS OF THE ASME (2020)

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Review Chemistry, Physical

Current Status and Prospects of Polymer Powder 3D Printing Technologies

Yue Wang et al.

MATERIALS (2020)

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Article Engineering, Manufacturing

Stereolithography (SLA) 3D printing of an antihypertensive polyprintlet: Case study of an unexpected photopolymer-drug reaction

Xiaoyan Xu et al.

ADDITIVE MANUFACTURING (2020)

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Article Pharmacology & Pharmacy

3D printing: Principles and pharmaceutical applications of selective laser sintering

Atheer Awad et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Engineering, Manufacturing

Preparation and laser powder bed fusion of composite microspheres consisting of poly(lactic acid) and nano-hydroxyapatite

Dong Yan et al.

ADDITIVE MANUFACTURING (2020)

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Article Pharmacology & Pharmacy

Fabrication of high drug loading levetiracetam tablets using semi-solid extrusion 3D printing

Mengsuo Cui et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

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Review Engineering, Manufacturing

Biomedical Manufacturing: A Review of the Emerging Research and Applications

Roland Chen et al.

JOURNAL OF MANUFACTURING SCIENCE AND ENGINEERING-TRANSACTIONS OF THE ASME (2020)

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Article Chemistry, Applied

Hot melt extrusion paired fused deposition modeling 3D printing to develop hydroxypropyl cellulose based floating tablets of cinnarizine

Anh Q. Vo et al.

CARBOHYDRATE POLYMERS (2020)

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Article Engineering, Biomedical

Additive Manufacturing of a Point-of-Care Polypill: Fabrication of Concept Capsules of Complex Geometry with Bespoke Release against Cardiovascular Disease

Beatriz C. Pereira et al.

ADVANCED HEALTHCARE MATERIALS (2020)

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Article Polymer Science

3D Printing of Tunable Zero-Order Release Printlets

Fabrizio Fina et al.

POLYMERS (2020)

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Review Pharmacology & Pharmacy

Polymer Selection for Hot-Melt Extrusion Coupled to Fused Deposition Modelling in Pharmaceutics

Gabriela G. Pereira et al.

PHARMACEUTICS (2020)

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Review Pharmacology & Pharmacy

Advanced machine-learning techniques in drug discovery

Moe Elbadawi et al.

DRUG DISCOVERY TODAY (2020)

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Article Pharmacology & Pharmacy

I Spy with My Little Eye: A Paediatric Visual Preferences Survey of 3D Printed Tablets

Patricija Januskaite et al.

PHARMACEUTICS (2020)

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Article Engineering, Manufacturing

Effect of fine powder particles on quality of binder jetting parts

Hadi Miyanaji et al.

ADDITIVE MANUFACTURING (2020)

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Article Biochemistry & Molecular Biology

3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease

Iria Seoane-Viano et al.

BIOMEDICINES (2020)

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Article Pharmacology & Pharmacy

M3DISEEN: A novel machine learning approach for predicting the 3D printability of medicines

Moe Elbadawi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

3D printing tablets: Predicting printability and drug dissolution from rheological data

Moe Elbadawi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Chemistry, Physical

Multivariate Design of 3D Printed Immediate-Release Tablets with Liquid Crystal-Forming Drug-Itraconazole

Witold Jamroz et al.

MATERIALS (2020)

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Article Engineering, Biomedical

Guided cell migration on a graded micropillar substrate

Srikumar Krishnamoorthy et al.

BIO-DESIGN AND MANUFACTURING (2020)

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Article Health Care Sciences & Services

A Feasibility Study of an Extrusion-Based Fabrication Process for Personalized Drugs

Ilhan Yu et al.

JOURNAL OF PERSONALIZED MEDICINE (2020)

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Article Business

Precision Medicine: Implications for value chains and business models in life sciences

Stefano Denicolai et al.

TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE (2020)

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Article Engineering, Biomedical

A high-throughput three-dimensional cell culture platform for drug screening

Jingyu Ock et al.

BIO-DESIGN AND MANUFACTURING (2020)

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Review Engineering, Biomedical

Digital Light Processing Based Three-dimensional Printing for Medical Applications

Jiumeng Zhang et al.

INTERNATIONAL JOURNAL OF BIOPRINTING (2020)

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Article Radiology, Nuclear Medicine & Medical Imaging

3D Printed Antibiotic and Chemotherapeutic Eluting Catheters for Potential Use in Interventional Radiology: In Vitro Proof of Concept Study

Jeffery A. Weisman et al.

ACADEMIC RADIOLOGY (2019)

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Article Pharmacology & Pharmacy

The applicability of pharmaceutical polymeric blends for the fused deposition modelling (FDM) 3D technique: Material considerations-printability-process modulation, with consecutive effects on in vitro release, stability and degradation

Kinga Ilyes et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

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Article Pharmacology & Pharmacy

'Temporary Plasticiser': A novel solution to fabricate 3D printed patient-centred cardiovascular 'Polypill' architectures

Beatriz C. Pereira et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

Retentive device for intravesical drug delivery based on water-induced shape memory response of poly(vinyl alcohol): design concept and 4D printing feasibility

A. Melocchi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Engineering, Electrical & Electronic

Biodegradable polymer material based smart stent: Wireless pressure sensor and 3D printed stent

Jongsung Park et al.

MICROELECTRONIC ENGINEERING (2019)

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Review Biotechnology & Applied Microbiology

Wearable biosensors for healthcare monitoring

Jayoung Kim et al.

NATURE BIOTECHNOLOGY (2019)

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Article Pharmacology & Pharmacy

3D Printed Pellets (Miniprintlets): A Novel, Multi-Drug, Controlled Release Platform Technology

Atheer Awad et al.

PHARMACEUTICS (2019)

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Editorial Material Chemistry, Medicinal

Cryptopharmaceuticals: Increasing the Safety of Medication by a Blockchain of Pharmaceutical Products

Lasse Norfeldt et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

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Article Chemistry, Multidisciplinary

A Proof of Concept for 3D Printing of Solid Lipid-Based Formulations of Poorly Water-Soluble Drugs to Control Formulation Dispersion Kinetics

Kapilkumar Vithani et al.

PHARMACEUTICAL RESEARCH (2019)

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Article Materials Science, Biomaterials

Development of a 3D-Printed Drug-Eluting Stent for Treating Obstructive Salivary Gland Disease

Tae Ho Kim et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2019)

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Article Pharmacology & Pharmacy

Quantification of Inkjet-Printed Pharmaceuticals on Porous Substrates Using Raman Spectroscopy and Near-Infrared Spectroscopy

Magnus Edinger et al.

AAPS PHARMSCITECH (2019)

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Article Pharmacology & Pharmacy

Digital light processing (DLP) 3D-printing technology and photoreactive polymers in fabrication of modified-release tablets

Hossam Kadry et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

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Article Pharmacology & Pharmacy

3D printed oral theophylline doses with innovative 'radiator-like' design: Impact of polyethylene oxide (PEO) molecular weight

Abdullah Isreb et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

Feasibility study into the potential use of fused-deposition modeling to manufacture 3D-printed enteric capsules in compounding pharmacies

Christoph Nober et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

3D Printing of a Multi-Layered Polypill Containing Six Drugs Using a Novel Stereolithographic Method

Pamela Robles-Martinez et al.

PHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

Towards Printed Pediatric Medicines in Hospital Pharmacies: Comparison of 2D and 3D-Printed Orodispersible Warfarin Films with Conventional Oral Powders in Unit Dose Sachets

Heidi Oblom et al.

PHARMACEUTICS (2019)

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Article Engineering, Manufacturing

Selective laser sintering and multi jet fusion: Process-induced modification of the raw materials and analyses of parts performance

Francesco Sillani et al.

ADDITIVE MANUFACTURING (2019)

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Article Pharmacology & Pharmacy

Direct powder extrusion 3D printing: Fabrication of drug products using a novel single-step process

Alvaro Goyanes et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

Automated therapy preparation of isoleucine formulations using 3D printing for the treatment of MSUD: First single-centre, prospective, crossover study in patients

Alvaro Goyanes et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Review Engineering, Manufacturing

Binder jetting: A review of process, materials, and methods

Mohsen Ziaee et al.

ADDITIVE MANUFACTURING (2019)

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Article Engineering, Manufacturing

Influence of resin infiltrants on mechanical and thermal performance in plaster binder jetting additive manufacturing

Timothy J. Ayres et al.

ADDITIVE MANUFACTURING (2019)

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Article Pharmacology & Pharmacy

Unidirectional drug release from 3D printed mucoadhesive buccal films using FDM technology: In vitro and ex vivo evaluation

Georgios K. Eleftheriadis et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

Abuse Deterrent Immediate Release Egg-Shaped Tablet (Egglets) Using 3D Printing Technology: Quality by Design to Optimize Drug Release and Extraction

Pavan Kumar Nukala et al.

AAPS PHARMSCITECH (2019)

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Article Pharmacology & Pharmacy

Embedded 3D Printing of Novel Bespoke Soft Dosage Form Concept for Pediatrics

Katarzyna Rycerz et al.

PHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

Printfills: 3D printed systems combining fused deposition modeling and injection volume filling. Application to colon-specific drug delivery

Vicente Linares et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

Development of mechanistic models to identify critical formulation and process variables of pastes for 3D printing of modified release tablets

Ahmed Zidan et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Pharmacology & Pharmacy

Extrudability analysis of drug loaded pastes for 3D printing of modified release tablets

Ahmed Zidan et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Materials Science, Multidisciplinary

Infiltration Behavior of Thermosets for Use in a Combined Selective Laser Sintering Process of Polymers

Katrin Wudy et al.

JOM (2019)

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Article Chemistry, Medicinal

Exploration and Preparation of a Dose-Flexible Regulation System for Levetiracetam Tablets via Novel Semi-Solid Extrusion Three-Dimensional Printing

Mengsuo Cui et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

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Article Chemistry, Medicinal

Roadmap to 3D-Printed Oral Pharmaceutical Dosage Forms: Feedstock Filament Properties and Characterization for Fused Deposition Modeling

Johanna Aho et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

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Article Pharmacology & Pharmacy

Hydrophilic excipients in digital light processing (DLP) printing of sustained release tablets: Impact on internal structure and drug dissolution rate

Mirjana Krkobabic et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Materials Science, Multidisciplinary

3D-Printed Gastric Resident Electronics

Yong Lin Kong et al.

ADVANCED MATERIALS TECHNOLOGIES (2019)

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Article Engineering, Biomedical

Rapid 3D printing of functional nanoparticle-enhanced conduits for effective nerve repair

Jie Tao et al.

ACTA BIOMATERIALIA (2019)

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Article Engineering, Biomedical

Thermal inkjet bioprinting triggers the activation of the VEGF pathway in human microvascular endothelial cells in vitro

Luis H. Solis et al.

BIOFABRICATION (2019)

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Review Cell Biology

Smart polymers for cell therapy and precision medicine

Hung-Jin Huang et al.

JOURNAL OF BIOMEDICAL SCIENCE (2019)

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Article Mathematical & Computational Biology

Additive manufacturing of specific ankle-foot orthoses for persons after stroke: A preliminary study based on gait analysis data

Zhen Liu et al.

MATHEMATICAL BIOSCIENCES AND ENGINEERING (2019)

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Article Multidisciplinary Sciences

α-Gluco-oligosaccharide in the research and development of a polymeric material for modified drug delivery

Frederico Minardi de Oliveira et al.

HELIYON (2019)

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Article Automation & Control Systems

Ingestible Osmotic Pill for In Vivo Sampling of Gut Microbiomes

Hojatollah Rezaei Nejad et al.

ADVANCED INTELLIGENT SYSTEMS (2019)

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Review Materials Science, Multidisciplinary

Photopolymerization in 3D Printing

Ali Bagheri et al.

ACS APPLIED POLYMER MATERIALS (2019)

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Article Pharmacology & Pharmacy

The Effect of Inkjet Printing over Polymeric Films as Potential Buccal Biologics Delivery Systems

Miguel Montenegro-Nicolini et al.

AAPS PHARMSCITECH (2018)

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Article Pharmacology & Pharmacy

Industrial Development of a 3D-Printed Nutraceutical Delivery Platform in the Form of a Multicompartment HPC Capsule

Alice Melocchi et al.

AAPS PHARMSCITECH (2018)

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Article Pharmacology & Pharmacy

Influence of Geometry on the Drug Release Profiles of Stereolithographic (SLA) 3D-Printed Tablets

Pamela Robles Martinez et al.

AAPS PHARMSCITECH (2018)

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Review Chemistry, Physical

Additive Manufacturing Technologies: 3D Printing in Organic Synthesis

Sergio Rossi et al.

CHEMCATCHEM (2018)

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Article Engineering, Environmental

3D printed polyvinyl alcohol ferrate(VI) capsules: Effective means for the removal of pharmaceuticals and illicit drugs from wastewater

Marianna Czolderova et al.

CHEMICAL ENGINEERING JOURNAL (2018)

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Review Pharmacology & Pharmacy

Reshaping drug development using 3D printing

Atheer Awad et al.

DRUG DISCOVERY TODAY (2018)

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Article Pharmacology & Pharmacy

A 3D printed bilayer oral solid dosage form combining metformin for prolonged and glimepiride for immediate drug delivery

Christos I. Gioumouxouzis et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

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Article Pharmacology & Pharmacy

Fabricating 3D printed orally disintegrating printlets using selective laser sintering

Fabrizio Fina et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Article Pharmacology & Pharmacy

PET/CT imaging of 3D printed devices in the gastrointestinal tract of rodents

Alvaro Goyanes et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Article Pharmacology & Pharmacy

Low temperature fused deposition modeling (FDM) 3D printing of thermolabile drugs

Gayathri Kollamaram et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Review Pharmacology & Pharmacy

3D printed medicines: A new branch of digital healthcare

Atheer Awad et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Article Pharmacology & Pharmacy

3D printing of drug-loaded gyroid lattices using selective laser sintering

Fabrizio Fina et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Article Chemistry, Multidisciplinary

Spatially controlled coating of continuous liquid interface production microneedles for transdermal protein delivery

Cassie L. Caudill et al.

JOURNAL OF CONTROLLED RELEASE (2018)

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Article Chemistry, Multidisciplinary

Channelled tablets: An innovative approach to accelerating drug release from 3D printed tablets

Muzna Sadia et al.

JOURNAL OF CONTROLLED RELEASE (2018)

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Article Chemistry, Medicinal

Formulation of 3D Printed Tablet for Rapid Drug Release by Fused Deposition Modeling: Screening Polymers for Drug Release, Drug-Polymer Miscibility and Printability

Nayan G. Solanki et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

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Article Chemistry, Medicinal

The Application of 3D Printing in the Formulation of Multilayered Fast Dissolving Oral Films

Touraj Ehtezazi et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

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Article Chemistry, Multidisciplinary

3D Printed Starmix Drug Loaded Dosage Forms for Paediatric Applications

Nicolaos Scoutaris et al.

PHARMACEUTICAL RESEARCH (2018)

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Article Chemistry, Multidisciplinary

Immediate Release 3D-Printed Tablets Produced Via Fused Deposition Modeling of a Thermo-Sensitive Drug

Wiebke Kempin et al.

PHARMACEUTICAL RESEARCH (2018)

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Article Green & Sustainable Science & Technology

Energy savings through additive manufacturing: an analysis of selective laser sintering for automotive and aircraft components

Tim Hettesheimer et al.

ENERGY EFFICIENCY (2018)

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Article Multidisciplinary Sciences

Electron beam melting in the fabrication of three-dimensional mesh titanium mandibular prosthesis scaffold

Rongzeng Yan et al.

SCIENTIFIC REPORTS (2018)

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Article Engineering, Biomedical

Programming of Multicomponent Temporal Release Profiles in 3D Printed Polypills via Core-Shell, Multilayer, and Gradient Concentration Profiles

Alexander P. Haring et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Review Pharmacology & Pharmacy

Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning

Sigrid A. Langhans

FRONTIERS IN PHARMACOLOGY (2018)

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Article Multidisciplinary Sciences

3D printing of a wearable personalized oral delivery device: A first-in-human study

Kun Liang et al.

SCIENCE ADVANCES (2018)

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Review Pharmacology & Pharmacy

Additive Manufacturing with 3D Printing: Progress from Bench to Bedside

Ziyaur Rahman et al.

AAPS JOURNAL (2018)

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Article Ethics

Solidarity and the problem of structural injustice in healthcare

Carol C. Gould

BIOETHICS (2018)

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Article Pharmacology & Pharmacy

Personalized orodispersible films by hot melt ram extrusion 3D printing

Umberto M. Musazzi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Article Pharmacology & Pharmacy

3D printed capsules for quantitative regional absorption studies in the GI tract

Derrick Smith et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Article Multidisciplinary Sciences

Acoustophoretic printing

Daniele Foresti et al.

SCIENCE ADVANCES (2018)

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Article Materials Science, Biomaterials

Selective Laser Melting of Integrated Ti6Al4V ELI Permeable Walls for Controlled Drug Delivery of Vancomycin

Martin B. Bezuidenhout et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)

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Review Engineering, Manufacturing

Additive manufacturing of pharmaceuticals for precision medicine applications: A review of the promises and perils in implementation

Megha Trivedi et al.

ADDITIVE MANUFACTURING (2018)

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Article Engineering, Manufacturing

Tailoring selective laser melting process for titanium drug-delivering implants with releasing micro-channels

Hany Hassanin et al.

ADDITIVE MANUFACTURING (2018)

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Article Engineering, Manufacturing

3D printing a mechanically-tunable acrylate resin on a commercial DLP-SLA printer

Joseph Borrello et al.

ADDITIVE MANUFACTURING (2018)

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Review Pharmacology & Pharmacy

Application of Fused Deposition Modelling (FDM) Method of 3D Printing in Drug Delivery

Jingjunjiao Long et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

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Article Chemistry, Multidisciplinary

Fabricating a Shell-Core Delayed Release Tablet Using Dual FDM 3D Printing for Patient-Centred Therapy

Tochukwu C. Okwuosa et al.

PHARMACEUTICAL RESEARCH (2017)

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Article Surgery

3D Printed Surgical Instruments: The Design and Fabrication Process

Mitchell George et al.

WORLD JOURNAL OF SURGERY (2017)

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Article Pharmacology & Pharmacy

Patient-specific 3D scanned and 3D printed antimicrobial polycaprolactone wound dressings

Zaid Muwaffak et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Pharmacology & Pharmacy

Patient acceptability of 3D printed medicines

Alvaro Goyanes et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Pharmacology & Pharmacy

Fabrication of drug-loaded hydrogels with stereolithographic 3D printing

Pamela Robles Martinez et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Pharmacology & Pharmacy

Development of modified release 3D printed tablets (printlets) with pharmaceutical excipients using additive manufacturing

Alvaro Goyanes et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Pharmacology & Pharmacy

Coupling 3D printing with hot-melt extrusion to produce controlled-release tablets

Jiaxiang Zhang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Pharmacology & Pharmacy

3D printed orodispersible films with Aripiprazole

Witold Jamroz et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Chemistry, Multidisciplinary

3D printed multi-compartment capsular devices for two-pulse oral drug delivery

A. Maroni et al.

JOURNAL OF CONTROLLED RELEASE (2017)

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Article Chemistry, Multidisciplinary

Anti-tuberculosis drug combination for controlled oral delivery using 3D printed compartmental dosage forms: From drug product design to in vivo testing

Natalja Genina et al.

JOURNAL OF CONTROLLED RELEASE (2017)

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Review Biochemical Research Methods

Tissue chips - innovative tools for drug development and disease modeling

L. A. Low et al.

LAB ON A CHIP (2017)

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Article Health Care Sciences & Services

A 3D-Printed Sensor for Monitoring Biosignals in Small Animals

Sung-Joon Cho et al.

JOURNAL OF HEALTHCARE ENGINEERING (2017)

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Review Materials Science, Biomaterials

Microvalve-based bioprinting - process, bio-inks and applications

Wei Long Ng et al.

BIOMATERIALS SCIENCE (2017)

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Review Geriatrics & Gerontology

What is polypharmacy? A systematic review of definitions

Nashwa Masnoon et al.

BMC GERIATRICS (2017)

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Article Multidisciplinary Sciences

Medication eluting devices for the field of OBGYN (MEDOBGYN): 3D printed biodegradable hormone eluting constructs, a proof of concept study

Karthik Tappa et al.

PLOS ONE (2017)

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Article Multidisciplinary Sciences

Fused Deposition Modeling (FDM) 3D Printed Tablets for Intragastric Floating Delivery of Domperidone

Xuyu Chai et al.

SCIENTIFIC REPORTS (2017)

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Review Biochemistry & Molecular Biology

3-D bioprinting technologies in tissue engineering and regenerative medicine: Current and future trends

Elliot S. Bishop et al.

GENES & DISEASES (2017)

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Article Engineering, Biomedical

Selective laser melting porous metallic implants with immobilized silver nanoparticles kill and prevent biofilm formation by methicillin-resistant Staphylococcus aureus

Ingmar A. J. van Hengel et al.

BIOMATERIALS (2017)

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Review Chemistry, Physical

Additive Manufacturing Processes: Selective Laser Melting, Electron Beam Melting and Binder JettingSelection Guidelines

Prashanth Konda Gokuldoss et al.

MATERIALS (2017)

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Article Engineering, Environmental

Assessing and Reducing the Toxicity of 3D-Printed Parts

Shirin Mesbah Oskui et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS (2016)

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Review Chemistry, Multidisciplinary

3D Bioprinting of Tissue/Organ Models

Falguni Pati et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

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Article Pharmacology & Pharmacy

Ethylene vinyl acetate (EVA) as a new drug carrier for 3D printed medical drug delivery devices

Natalja Genina et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

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Article Pharmacology & Pharmacy

Stereolithographic (SLA) 3D printing of oral modified-release dosage forms

Jie Wang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)

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Review Pharmacology & Pharmacy

3D printing in pharmaceutics: A new tool for designing customized drug delivery systems

Goole Jonathan et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)

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Review Materials Science, Multidisciplinary

The metallurgy and processing science of metal additive manufacturing

W. J. Sames et al.

INTERNATIONAL MATERIALS REVIEWS (2016)

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Article Chemistry, Multidisciplinary

3D scanning and 3D printing as innovative technologies for fabricating personalized topical drug delivery systems

Alvaro Goyanes et al.

JOURNAL OF CONTROLLED RELEASE (2016)

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Article Dentistry, Oral Surgery & Medicine

A selective laser sintering prototype guide used to fabricate immediate interim fixed complete arch prostheses in flapless dental implant surgery: Technique description and clinical results

Giovanni de A.P. Di Giacomo et al.

JOURNAL OF PROSTHETIC DENTISTRY (2016)

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Article Biochemical Research Methods

3D printed microfluidic circuitry via multijet-based additive manufacturing

R. D. Sochol et al.

LAB ON A CHIP (2016)

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Review Materials Science, Multidisciplinary

Low temperature additive manufacturing of three dimensional scaffolds for bone-tissue engineering applications: Processing related challenges and property assessment

Alok Kumar et al.

MATERIALS SCIENCE & ENGINEERING R-REPORTS (2016)

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Article Chemistry, Multidisciplinary

A Lower Temperature FDM 3D Printing for the Manufacture of Patient-Specific Immediate Release Tablets

Tochukwu C. Okwuosa et al.

PHARMACEUTICAL RESEARCH (2016)

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Review Cell & Tissue Engineering

Three-dimensional bio-printing equipment technologies for tissue engineering and regenerative medicine

Sang Hyun Ahn et al.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2016)

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Article Multidisciplinary Sciences

Establishing Antibacterial Multilayer Films on the Surface of Direct Metal Laser Sintered Titanium Primed with Phase-Transited Lysozyme

Binbin Guan et al.

SCIENTIFIC REPORTS (2016)

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Review Cell & Tissue Engineering

Three-dimensional bio-printing equipment technologies for tissue engineering and regenerative medicine

Sang Hyun Ahn et al.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2016)

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Proceedings Paper Engineering, Biomedical

PCL/Ibuprofen Implants Fabricated by Selective Laser Sintering for Orbital Repair

G. V. Salmoria et al.

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Fabrication of extended-release patient-tailored prednisolone tablets via fused deposition modelling (FDM) 3D printing

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3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets

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Hyperspectral imaging in quality control of inkjet printed personalised dosage forms

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INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)

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Rheology as a tool for evaluation of melt processability of innovative dosage forms

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Personalised dosing: Printing a dose of one's own medicine

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Fabrication of controlled-release budesonide tablets via desktop (FDM) 3D printing

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3D printing of tablets containing multiple drugs with defined release profiles

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INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)

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Effect of geometry on drug release from 3D printed tablets

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3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles

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3D printing by fused deposition modeling (FDM) of a swellable/erodible capsular device for oral pulsatile release of drugs

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Fabrication of a three-dimensional tissue model microarray using laser foaming of a gas-impregnated biodegradable polymer

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Accuracy of tablet splitting: Comparison study between hand splitting and tablet cutter

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Rapid interferometric imaging of printed drug laden multilayer structures

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SiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivo

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Melt extrusion with poorly soluble drugs

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Microstructures and Mechanical Properties of Ti6Al4V Parts Fabricated by Selective Laser Melting and Electron Beam Melting

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Metal Fabrication by Additive Manufacturing Using Laser and Electron Beam Melting Technologies

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Determination of acetaminophen's solubility in poly(ethylene oxide) by rheological, thermal and microscopic methods

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ANNUAL REVIEW OF MATERIALS RESEARCH, VOL 40 (2010)

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On-Demand Three-Dimensional Freeform Fabrication of Multi-Layered Hydrogel Scaffold With Fluidic Channels

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Cell Damage Evaluation of Thermal Inkjet Printed Chinese Hamster Ovary Cells

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Editorial Material Medicine, General & Internal

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A novel fast disintegrating tablet fabricated by three-dimensional printing

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DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2009)

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Dimensional error of selective laser sintering, three-dimensional printing and PolyJet™ models in the reproduction of mandibular anatomy

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Analysis of Drug Content and Weight Uniformity for Half-Tablets of 6 Commonly Split Medications

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A review of process development steps for new material systems in three dimensional printing (3DP)

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Journal of Manufacturing Processes (2009)

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Delivery of human fibroblast cells by piezoelectric drop-on-demand inkjet printing

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Selective laser sintering technology for customized fabrication of facial prostheses

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EXPERT OPINION ON DRUG DELIVERY (2007)

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Hydrogels synthesised through photoinitiator-free photopolymerisation technique for delivering drugs including a tumour-tracing porphyrin

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Development of near zero-order release dosage forms using three-dimensional printing (3-DP (TM)) technology

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Development of a microscale cell culture analog to probe naphthalene toxicity

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Letter Medicine, General & Internal

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)

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A Review of State-of-the-Art on Enabling Additive Manufacturing Processes for Precision Medicine

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