Letter to the Editor: Assessing the Effect of Thrombectomy up to 24h After Onset of Stroke Requires Large, Prospective, International Studies

Article Neuroimaging

Endovascular therapy with or without intravenous thrombolysis in acute stroke with tandem occlusion

Mohammad Anadani et al.

Summary: This study compared the treatment effects of EVT alone and EVT plus IVT in patients with acute ischemic stroke due to anterior tandem occlusions. The results showed higher odds of favorable and excellent outcomes, as well as successful reperfusion in the IVT+ group, without a difference in the risk of significant hemorrhagic complications. Secondary analysis also indicated better outcomes with bridging therapy in patients treated with acute cervical internal carotid artery stenting.

JOURNAL OF NEUROINTERVENTIONAL SURGERY (2022)

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Review Clinical Neurology

Endovascular Treatment for Posterior Circulation Stroke: Ways to Maximize Therapeutic Efficacy

Seong-Joon Lee et al.

Summary: The efficacy of endovascular treatment (EVT) in posterior circulation stroke (PC-EVT) is still uncertain. While some studies have shown no improvement in functional outcomes with EVT for PC-EVT, there are promising results from recent trials. Factors such as baseline clinical severity, infarct volume, collaterals, and time metrics need to be further studied to identify prognostic factors beyond recanalization. Additionally, individualized patient selection for PC-EVT and technical considerations for improving treatment efficacy are discussed.

JOURNAL OF STROKE (2022)

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Article Neurosciences

Thrombectomy in acute ischemic stroke in the extended time window: Real-life experience in a high-volume center

Pekka Virtanen et al.

Summary: The study evaluated the outcomes of patients with acute ischemic stroke who underwent endovascular thrombectomy in the extended time window and compared the results between patients who met the criteria of two landmark randomized controlled trials (DAWN and DEFUSE-3) and those who did not. The findings highlight the importance of baseline ischemia and vessel status in selecting patients for endovascular thrombectomy and emphasize the need for further research in these patient subgroups.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2022)

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Article Medicine, General & Internal

Improving the Prognosis of Patients With Acute Ischemic Stroke Treated in the Late Time Window After the Introduction of Advanced Imaging Software: Benefits From Thrombectomy in the Extended Time Window

Taedong Ok et al.

Summary: This study compared the prognosis of ischemic stroke patients treated under the extended time indication before and after the introduction of advanced software. The results showed that the use of advanced imaging software led to an increase in the number of patients receiving treatment and improved prognosis among those treated based on the extended time indication.

JOURNAL OF KOREAN MEDICAL SCIENCE (2022)

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Article Clinical Neurology

A Multicenter Survey of Acute Stroke Imaging Protocols for Endovascular Thrombectomy

Byungjun Kim et al.

Summary: A survey of acute stroke imaging protocols for endovascular thrombectomy (EVT) at tertiary hospitals in South Korea revealed significant heterogeneity, with 69% adopting CT-based protocols and 31% MR-based protocols. The study suggests that hospitals refine their imaging protocols according to their specific conditions and needs.

NEUROINTERVENTION (2021)

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Article Clinical Neurology