Intravenous immunoglobulins in the treatment of post-COVID: A case-control study

Review Infectious Diseases

A clinical case definition of post-COVID-19 condition by a Delphi consensus

Joan B. Soriano et al.

Summary: People with COVID-19 might experience long-term symptoms known as long COVID or long-haul COVID. The lack of a standardized definition hinders the understanding and treatment of this condition. In a WHO-led Delphi process, a consensus definition was developed, stating that post-COVID-19 condition occurs in individuals with a history of SARS-CoV-2 infection, with symptoms lasting for at least 2 months and impacting everyday functioning. This common framework provides a foundation for future studies and therapy.

LANCET INFECTIOUS DISEASES (2022)

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Article Medicine, General & Internal

What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol

Louise Sigfrid et al.

Summary: Very little is currently known about the possible clinical sequelae that may persist after resolution of acute COVID-19. A recent longitudinal cohort study from Italy reported that 87% of patients had at least one ongoing symptom at 60-day follow-up after hospitalisation with COVID-19, suggesting that COVID-19 patients may require more psychological support than typical ICU patients. This study aims to characterize physical and psychosocial sequelae in patients post-COVID-19 hospital discharge and provide insights for long-term consequences prevention and clinical management.

BMJ OPEN (2021)

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Article Immunology

Efficacy of IVIG (intravenous immunoglobulin) for corona virus disease 2019 (COVID-19): A meta-analysis

Huai-rong Xiang et al.

Summary: The efficacy of IVIG therapy for patients with COVID-19 is controversial. A meta-analysis found clinical efficacy of IVIG in critical patients, but no significant difference in severe or non-severe patients.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

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Article Multidisciplinary Sciences

Diverse functional autoantibodies in patients with COVID-19

Eric Y. Wang et al.

Summary: COVID-19 patients show increased autoantibody reactivities against immunomodulatory proteins, which may affect immune function and lead to different clinical outcomes.

NATURE (2021)

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Review Biochemistry & Molecular Biology

Post-acute COVID-19 syndrome

Ani Nalbandian et al.

Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.

NATURE MEDICINE (2021)

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Review Health Care Sciences & Services

Back to the Future? Immunoglobulin Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Helen Brownlie et al.

Summary: Controlled trials on the use of intravenous immunoglobulin G (IV IgG) to treat ME/CFS have shown mixed results, but a detailed review suggests that the therapeutic potential of this intervention has been underestimated. IgG is highly effective for some severe and well-characterized ME/CFS patients, and this area of research should be revived.

HEALTHCARE (2021)

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Intravenous immunoglobulins in the treatment of post-COVID: A case-control study

相关参考文献

A clinical case definition of post-COVID-19 condition by a Delphi consensus

What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol

Efficacy of IVIG (intravenous immunoglobulin) for corona virus disease 2019 (COVID-19): A meta-analysis

Diverse functional autoantibodies in patients with COVID-19

Post-acute COVID-19 syndrome

Back to the Future? Immunoglobulin Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

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