Genomic evidence for reinfection with different Omicron subvariants

Letter Infectious Diseases

Detection of the Omicron BA.2.75 subvariant in Japan

Yosuke Hirotsu et al.

JOURNAL OF INFECTION (2023)

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Letter Infectious Diseases

SARS-CoV-2 Omicron sublineage BA.2 replaces BA.1.1: Genomic surveillance in Japan from September 2021 to March 2022

Yosuke Hirotsu et al.

JOURNAL OF INFECTION (2022)

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Article Multidisciplinary Sciences

Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement

Matthew McCallum et al.

Summary: The SARS-CoV-2 Omicron variant evades antibody-mediated immunity and exhibits enhanced affinity for host cells due to accumulation of spike mutations and remodeling of interactions with the ACE2 receptor.

SCIENCE (2022)

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Article Multidisciplinary Sciences

Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa

Juliet R. C. Pulliam et al.

Summary: This study provides two methods for monitoring reinfection trends in routine surveillance data. The results suggest immune evasion by the Omicron variant in previously infected individuals in South Africa, and there has been an increase in the risk of having a third infection since mid-November 2021.

SCIENCE (2022)

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Article Biochemistry & Molecular Biology

Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum

Aekkachai Tuekprakhon et al.

Summary: The Omicron variant of SARS-CoV-2 has rapidly spread globally and has evolved into different sublineages, with BA.4 and BA.5 dominating in South Africa. These sublineages show reduced neutralization by vaccine and naturally immune serum, indicating the possibility of repeat Omicron infections.

CELL (2022)

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Article Infectious Diseases

Classification of Omicron BA.1, BA.1.1, and BA.2 sublineages by TaqMan assay consistent with whole genome analysis data

Yosuke Hirotsu et al.

Summary: A TaqMan assay was developed to identify Omicron sublineage variants, showing high accuracy in distinguishing between different variants. The study analyzed 171 samples and found a concordance rate of 100% between whole genome sequencing results and the TaqMan assay, indicating the effectiveness of this method in variant identification.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2022)

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Letter Medicine, General & Internal

Protective Effect of Previous SARS- CoV-2 Infection against Omicron BA.4 and BA.5 Subvariants

Heba N. Altarawneh et al.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Letter Medicine, General & Internal

Risk of BA.5 Infection among Persons Exposed to Previous SARS-CoV-2 Variants

Joao Malato et al.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Letter Medicine, General & Internal

Protective Effect of Previous SARS-CoV-2 Infection against Omicron BA.4 and BA.5 Subvariants

Heba N. Altarawneh et al.

Summary: Prevention of Omicron can be achieved to some extent by previous SARS-CoV-2 infection, with an effectiveness of 35% for preventing reinfection with BA.4 and BA.5 subvariants and 76% for previous omicron infection.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Multidisciplinary Sciences

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

Donald J. Benton et al.

NATURE (2020)

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Genomic evidence for reinfection with different Omicron subvariants

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