☆ 4.8 Letter

Response to: Towards optimally replacing the current version of MELD

JOURNAL OF HEPATOLOGY (2023)

Beyond MELD - Emerging strategies and technologies for improving mortality prediction, organ allocation and outcomes in liver transplantation

Jin Ge et al.

Summary: This review article discusses the model for end-stage liver disease (MELD) score and its dual purpose in general and transplant hepatology. The article summarizes emerging concepts, methodologies, and technologies that may improve mortality prognostication in the future, and explores how these novel concepts and technologies may be incorporated into clinical practice.

JOURNAL OF HEPATOLOGY (2022)

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Article Gastroenterology & Hepatology

The Predictive Role of Model for End-Stage Liver Disease-Lactate and Lactate Clearance for In-Hospital Mortality Among a National Cirrhosis Cohort

Nadim Mahmud et al.

Summary: MELD-lactate shows superior discrimination in predicting in-hospital mortality among cirrhosis patients compared to traditional MELD or MELD-Na, especially in cases with MELD <= 15 and hospitalizations for infection. Incorporating day 3 lactate clearance may further improve prognostication.

LIVER TRANSPLANTATION (2021)

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Article Gastroenterology & Hepatology

MELD 3.0: The Model for End-Stage Liver Disease Updated for the Modern Era

W. Ray Kim et al.

Summary: The final MELD 3.0 model had better discrimination than MELDNa and accurately predicted mortality, particularly in female patients. It addresses determinants of wait list outcomes, including sex disparity, resulting in fewer wait list deaths compared to MELDNa.

GASTROENTEROLOGY (2021)

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Article Gastroenterology & Hepatology