An ultrasensitive ponceau 4R detection sensor based on molecularly imprinted electrode using pod-like cerium molybdate and multi-walled carbon nanotubes hybrids

The novel binary metal oxide cerium molybdate (Ce2Mo3O13) as a promising strategy can be combined with MWCNTs for the development of ultrasensitive sensors. Herein, a pod-like Ce2Mo3O13 was prepared, charac-terized, and used to construct a molecularly imprinted sensor (MIPs) for detection of ponceau 4 R as low as to nanomolar concentration. The results demonstrate that the electrochemical response at the specific hybridized electrode of MIPs/Ce2Mo3O13-MWCNTs/GCE is stronger than non-molecularly imprinted ones (NIPs). It in-dicates a synergistic effect resulting from the hybridized Ce2Mo3O13-MWCNTs combination and modification to the electrode. Under optimal conditions, the calibration curve is in the range of 10 nmol L-1 to 1 mu mol L-1, with a limit of detection of 7 nmol L-1 for ponceau 4 R determination. The excellent sensitivity, reproducibility, and selectivity of the new sensor provide an accurate and facile avenue for ultrasensitive ponceau 4 R detection in different samples.

Automated summary

In this study, a pod-like Ce2Mo3O13 was prepared and used to construct a highly sensitive molecularly imprinted sensor for the detection of ponceau 4 R at nanomolar concentrations. The results showed that the electrochemical response of the MIPs/Ce2Mo3O13-MWCNTs/GCE hybridized electrode was stronger than the non-molecularly imprinted ones, indicating a synergistic effect from the combination of Ce2Mo3O13-MWCNTs and modification to the electrode.