☆ 4.8 Review

Ultrasound nanotheranostics: Toward precision medicine

JOURNAL OF CONTROLLED RELEASE (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。
Article Engineering, Biomedical

Polymeric dual-modal imaging nanoprobe with two-photon aggregation-induced emission for fluorescence imaging and gadolinium-chelation for magnetic resonance imaging

Xueyang Xiao et al.

Summary: In this study, a dual-modality contrast agent, Gd-DOTA-TPBP, was successfully synthesized using an amphiphilic block polymer as a carrier. The contrast agent exhibited high resolution and sensitivity, making it a promising tool for early-stage tumor diagnosis.

BIOACTIVE MATERIALS (2023)

添加到收藏夹
Article Biochemical Research Methods

Targeted Anti-Cancer Provascular Therapy Using Ultrasound, Microbubbles, and Nitrite to Increase Radiotherapy Efficacy

Simon Michon et al.

Summary: Ultrasound targeted microbubble cavitation (UTMC) with a sodium nitrite coinjection can increase tumor blood perfusion and enhance the efficacy of radiation therapy.

BIOCONJUGATE CHEMISTRY (2022)

添加到收藏夹
Article Cell Biology

Ultrasound-targeted microbubble destruction-mediated miR-144-5p overexpression enhances the anti-tumor effect of paclitaxel on thyroid carcinoma by targeting STON2

Xuefeng Chen et al.

Summary: The effects of miR-144-5p and paclitaxel (PTX) on thyroid carcinoma were investigated in this study. MiR-144-5p was found to be low-expressed in thyroid carcinoma and directly down-regulated the level of STON2. Overexpression of miR-144-5p and treatment with PTX inhibited the viability, proliferation, migration, and invasion of thyroid carcinoma cells. Furthermore, miR-144-5p overexpression enhanced the inhibiting effect of PTX on tumor volume, weight, and Ki67 level in a xenotransplant tumor model. These effects were mediated by targeting STON2 and up-regulating E-cadherin expression while down-regulating MMP-9 and N-cadherin expression.

CELL CYCLE (2022)

添加到收藏夹
Article Pharmacology & Pharmacy

Multifunctional liposome for photoacoustic/ultrasound imaging-guided chemo/photothermal retinoblastoma therapy

Meng Li et al.

Summary: Retinoblastoma is a malignant intraocular neoplasm that commonly leads to delayed diagnosis and treatment. Researchers have developed a novel nanoplatform that allows both imaging and targeted treatment. This nanoplatform has excellent dual-modal imaging and photothermal therapy capabilities, and holds significant value in diagnosing and treating retinoblastoma.

DRUG DELIVERY (2022)

添加到收藏夹
Article Pharmacology & Pharmacy

Ultrasound-sensitive siRNA-loaded nanobubbles fabrication and antagonism in drug resistance for NSCLC

Chunhong Su et al.

Summary: In this study, nanobubbles loaded with PDLIM5 siRNA were prepared, and their transfection efficiency and antagonism in drug resistance for NSCLC were investigated in combination with ultrasound irradiation. The results showed that this approach can effectively inhibit tumor cell growth and promote apoptosis.

DRUG DELIVERY (2022)

添加到收藏夹
Article Pharmacology & Pharmacy

Gene and oligonucleotide delivery via micro- and nanobubbles by ultrasound exposure

Yoko Endo-Takahashi et al.

Summary: This review summarizes the use of micro-and nanobubbles in ultrasound-mediated gene and oligonucleotide delivery systems, and discusses their potential as therapeutic tools.

DRUG METABOLISM AND PHARMACOKINETICS (2022)

添加到收藏夹
Article Radiology, Nuclear Medicine & Medical Imaging

Detection and Characterization of Sentinel Lymph Node by Ultrasound Molecular Imaging with B7-H3-Targeted Microbubbles in Orthotopic Breast Cancer Model in Mice

Zhongqian Hu et al.

Summary: Accurate identification and assessment of sentinel lymph node (SLN) using noninvasive imaging methods, such as B7-H3-targeted molecular-ultrasound imaging, can play a vital role in tumor staging and prognostic evaluation. This study demonstrated the efficacy of B7-H3-targeted microbubbles for SLN detection and characterization in a mouse model of orthotopic breast cancer.

MOLECULAR IMAGING AND BIOLOGY (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Arterial Labeling Ultrasound Subtraction Angiography (ALUSA) Based on Acoustic Phase-Change Nanodroplets

Jian An et al.

Summary: This study develops a noninvasive arterial labeling ultrasound subtraction angiography (ALUSA) technique based on new nanodroplets, which allows high-resolution observation of vascular structures and perfusion. It has been successfully applied in rabbit kidneys and mouse breast tumors.

SMALL (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Engineering Responsive Ultrasound Contrast Agents Through Crosslinked Networks on Lipid-Shelled Microbubbles

Dragana Dubey et al.

Summary: Ultrasound imaging with contrast agents, especially lipid-shelled microbubbles, is crucial in clinical diagnostics. Recent studies have focused on the use of crosslinking and decrosslinking to alter the mechanical properties of microbubbles, allowing for the detection of soluble molecular targets. However, a systematic study of the influence of crosslinker concentration and structure on microbubble properties is lacking. This research aims to fill this gap and provides a framework for the development of responsive ultrasound contrast agents for molecular imaging.

SMALL (2022)

添加到收藏夹
Article Medicine, Research & Experimental

Ultrasound imaging tracking of mesenchymal stem cells intracellularly labeled with biosynthetic gas vesicles for treatment of rheumatoid arthritis

Zheli Gong et al.

Summary: The study aims to explore the therapeutic effect of GV-labeled MSCs in the treatment of RA under real-time in vivo imaging. The results indicate that GV@MSCs have good contrast and cell viability under ultrasound imaging and can be tracked in real-time in the animal model, demonstrating their ability to migrate and target the joints. Furthermore, the combination of GV@MSCs and MTX shows a significant therapeutic effect in the treatment of RA.

THERANOSTICS (2022)

添加到收藏夹
Article Pharmacology & Pharmacy

Ultrasound-Responsive Nrf2-Targeting siRNA-Loaded Nanobubbles for Enhancing the Treatment of Melanoma

Monica Argenziano et al.

Summary: siRNA-mediated inhibition of Nrf2 can overcome chemoresistance in malignant tumors. This study designed chitosan-shelled nanobubbles for delivering siRNA against Nrf2, with a new preparation method based on a water-oil-water double-emulsion. The results showed that nanobubbles have promise as a responsive tool for siRNA delivery, able to overcome chemoresistance in melanoma cancer cells.

PHARMACEUTICS (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Activatable Cancer Sono-Immunotherapy using Semiconducting Polymer Nanobodies

Ziling Zeng et al.

Summary: This study reports the development of semiconducting polymers as efficient sonosensitizers and the further development of sono-immunotherapeutic nanobodies. The strategy can achieve immunogenic cell death, release of anti-CTLA-4 antibodies, and promote tumor-killing function through sono-irradiation, providing important insights for precise spatiotemporal control over immunotherapy.

ADVANCED MATERIALS (2022)

添加到收藏夹
Article Biochemistry & Molecular Biology

Drug-loaded nanoparticles conjugated with genetically engineered bacteria for cancer therapy

Yan Du et al.

Summary: In this study, genetically engineered bacteria and drug-loaded nanoparticles were combined to enhance the therapeutic efficacy of high-intensity focused ultrasound (HIFU) tumor ablation therapy. The results showed that conjugating cationic lipid nanoparticles loaded with paclitaxel and perfluorohexane with genetically modified Escherichia coil enhanced the treatment efficacy.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)

添加到收藏夹
Article Biochemical Research Methods

Rapid Copper-free Click Conjugation to Lipid-Shelled Microbubbles for Ultrasound Molecular Imaging of Murine Bowel Inflammation

Una Goncin et al.

Summary: Microbubbles were labeled with P-selectin using an azide-DBCO reaction, which showed similar imaging capabilities for detecting bowel inflammation compared to the traditional biotin-streptavidin labeling approach. This click chemistry conjugation method has the potential to be a quick, cost-efficient, and clinically translatable approach for developing targeted microbubbles.

BIOCONJUGATE CHEMISTRY (2022)

添加到收藏夹
Article Medicine, Research & Experimental

Ultrasound-triggered drug delivery for glioma therapy through gambogic acid-loaded nanobubble-microbubble complexes

Feng Wang et al.

Summary: In this study, negatively charged GA-loaded PLGA nanobubbles were successfully conjugated onto the surface of cationic lipid microbubbles. Through the assistance of low-intensity focused ultrasound, the delivery of GA into the brain and tumor cells was significantly enhanced, leading to an increased efficacy in inhibiting tumor growth.

BIOMEDICINE & PHARMACOTHERAPY (2022)

添加到收藏夹
Review Biochemical Research Methods

Application of nanotechnology in medical diagnosis and imaging

Amit Singh et al.

Summary: Nanotechnology has greatly impacted the advancement in disease imaging, early detection, diagnosis, and prognosis. The unique properties of nanoparticles enable contrast enhancement for biomedical imaging and molecular level tissue-specific diagnosis. Small variations in nanoparticle size or composition can result in significant changes in their optical, magnetic, or electrical properties, allowing for unique possibilities of multiplexing.

CURRENT OPINION IN BIOTECHNOLOGY (2022)

添加到收藏夹
Article Pharmacology & Pharmacy

Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation

Jing Zheng et al.

Summary: In this study, the effects and potential mechanism of sonodynamic therapy (SDT) on ovarian cancer were investigated. The results showed that SDT mediated by nanoparticles promoted apoptosis of ovarian cancer cells and enhanced the immune response.

DRUG DELIVERY (2022)

添加到收藏夹
Article Pharmacology & Pharmacy

Contrast-enhanced ultrasound imaging using long-circulating cationic magnetic microbubbles in vitro and in vivo validations

Yingying Liu et al.

Summary: In this study, a novel cationic magnetic microbubble (MBM) was developed, which could achieve targeted aggregation under a magnetic field and real-time visualization using ultrasound. These microbubbles had good biocompatibility, enhanced ultrasound contrast, and could accumulate in the target site through magnetic targeting.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

FN3 linked nanobubbles as a targeted contrast agent for US imaging of cancer-associated human PD-L1

Uday S. Kumar et al.

Summary: PD-L1 targeted therapies may be effective for various cancers. Non-invasive diagnostic and prognostic molecular imaging platforms can enhance clinical assessment of PD-L1 tumor status. By utilizing ultra-stable nanobubbles as a contrast agent, functionalized with nanobody targeting human PD-L1, molecular imaging of the tumor is possible. The results showed a three-fold increase in contrast signal compared to non-targeted nanobubbles. This research has the potential for clinical translation and prognostic evaluation of patient response to PD-L1 targeted immunotherapy.

JOURNAL OF CONTROLLED RELEASE (2022)

添加到收藏夹
Review Nanoscience & Nanotechnology

Therapeutic gas delivery strategies

Wanjun Gong et al.

Summary: Gas molecules with pharmaceutical effects show potential in disease treatment, with various strategies explored for improving gas delivery efficiency and controllable gas release. Future gas therapy may involve intelligent gas delivery strategies and catalyst use to enhance effectiveness.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Ultrasound Molecular Imaging for Multiple Biomarkers by Serial Collapse of Targeting Microbubbles with Distinct Acoustic Pressures

Zhenzhou Li et al.

Summary: Ultrasound molecular imaging (UMI) shows promise in simultaneously detecting multiple biomarkers and predicting invasive behavior of tumors.

SMALL (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Magnetic Nanobubble Mechanical Stress Induces the Piezo1-Ca2+-BMP2/Smad Pathway to Modulate Neural Stem Cell Fate and MRI/Ultrasound Dual Imaging Surveillance for Ischemic Stroke

Jing Li et al.

Summary: Magnetic nanobubbles can modulate the differentiation of neural stem cells through the activation of mechanosensory channels and biochemical signaling pathways, potentially improving their clinical applications.

SMALL (2022)

添加到收藏夹
Article Biotechnology & Applied Microbiology

Ultrasound and magnetic resonance imaging of cyclic arginine glycine aspartic acid-gadopentetic acid-polylactic acid in human breast cancer by targeting αvβ3 in xenograft-bearing nude mice

Danhui Fu et al.

Summary: This study successfully developed a targeted contrast agent for MRI/ultrasound dual-modality molecular radiography for breast cancer, which showed potential in early detection, diagnosis of metastasis, and dynamic evaluation of the efficacy of molecular targeted therapy of integrin alpha v beta 3.

BIOENGINEERED (2022)

添加到收藏夹
Article Oncology

Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells

Lei Chen et al.

Summary: Sonodynamic therapy (SDT) is a non-invasive technique that destroys tumor cells through mitochondrial respiratory chain damage and increased intracellular reactive oxygen species (ROS) and calcium overload levels. This study found that the early application of the mechanosensitive Ca2+ channel antagonist GsMTx4 can enhance the anti-tumor effect of SDT by promoting the dissociation and polymerization of the Ca2+ lipid complex and increasing oxidative stress levels. The study also revealed the mechanism of intracellular Ca2+ signal regulation, lipid metabolism, and recruitment of macrophages in glioma treatment.

CANCERS (2022)

添加到收藏夹
Review Oncology

Low-Intensity Focused Ultrasound Technique in Glioblastoma Multiforme Treatment

Rajneesh Mungur et al.

Summary: The use of LIFU+MBs in drug delivery for glioblastoma has shown to be a safe and effective method, with improved drug uptake and tumor control without causing harm to brain structures.

FRONTIERS IN ONCOLOGY (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Immunosonodynamic Therapy Designed with Activatable Sonosensitizer and Immune Stimulant Imiquimod

Huali Lei et al.

Summary: This study presents the concept of a next-generation sonodynamic sensitizer preparation for immunosonodynamic therapy (iSDT) as a noninvasive synergistic therapeutic modality. By combining sonodynamic therapy and immunotherapy, this method achieves efficient and targeted treatment for tumors. The iSDT specifically activates the sonodynamic effect at the tumor site, showing high specificity in killing tumor cells. Additionally, when combined with an alpha-PD-L1 antibody, this therapy effectively inhibits tumor metastasis.

ACS NANO (2022)

添加到收藏夹
Article Engineering, Environmental

Tri-component programmable nanoregulator with Three-pronged penetration boosts immunotherapy of Triple-Negative breast cancer

Ziying Li et al.

Summary: This study developed a nanoregulator ORM that can improve the treatment of triple-negative breast cancer by modulating the tumor microenvironment and enhancing immunotherapy. ORM showed remarkable inhibition of primary and distant tumors by reshaping the tumor immune microenvironment.

CHEMICAL ENGINEERING JOURNAL (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain

Koki Ogawa et al.

Summary: This study investigated the use of microbubble-assisted focused ultrasound blood-brain barrier opening for the intravenous delivery of mRNA-LNP. The results showed that exogenous protein expression by mRNA-LNP occurred only when FUS and microbubbles were applied to the brain.

JOURNAL OF CONTROLLED RELEASE (2022)

添加到收藏夹
Article Engineering, Biomedical

Multiplexed Ultrasound Imaging Using Spectral Analysis on Gas Vesicles

Sangnam Kim et al.

Summary: This study investigates the use of mid-band fit (MBF) spectral imaging to achieve multiplexed ultrasound imaging and visualize the locations of different types of stationary gas vesicles (GVs). The technique is successfully applied to agarose gel phantoms and ex vivo mouse liver specimens, effectively localizing and distinguishing clustered GVs from unclustered GVs. Mouse macrophages are used as carriers of GVs and act as beacons to report cell locations. The study demonstrates a novel approach for visualizing biological tissues and offers potential applications in biomedical research.

ADVANCED HEALTHCARE MATERIALS (2022)

添加到收藏夹
Review Polymer Science

A Review of Polymeric Micelles and Their Applications

Suguna Perumal et al.

Summary: This review discusses the self-assembly of amphiphilic polymers into micelles (polymeric nanoparticles) and their importance in bio-applications. Micelles, with their unique properties, size, shape, and biocompatibility, enhance drug loading and target release, making them a research focus in the field of biomedicine.

POLYMERS (2022)

添加到收藏夹
Review Pharmacology & Pharmacy

Microbubbles Stabilized by Protein Shell: From Pioneering Ultrasound Contrast Agents to Advanced Theranostic Systems

Polina G. Rudakovskaya et al.

Summary: This review provides a comprehensive summary and critical evaluation of known protein microbubbles over decades, aiming to optimize their safety and imaging efficiency, as well as exploring biomedical applications beyond ultrasound imaging.

PHARMACEUTICS (2022)

添加到收藏夹
Article Pharmacology & Pharmacy

Biosynthetic Gas Vesicles from Halobacteria NRC-1: A Potential Ultrasound Contrast Agent for Tumor Imaging

Mingjie Wei et al.

Summary: The rugby-ball-shaped GVs isolated from Halobacteria NRC-1 exhibit excellent ultrasound contrast imaging properties and show potential for future molecular imaging and image-guided drug delivery. They can produce stable and strong contrast signals in murine liver tumors, and have a higher penetration ability compared to traditional microbubbles in ischemic regions of tumors.

PHARMACEUTICS (2022)

添加到收藏夹
Review Neurosciences

Ultrasound-Mediated Bioeffects in Senescent Mice and Alzheimer's Mouse Models

Matilde Balbi et al.

Summary: Ultrasound is widely used in diagnostic imaging and has shown potential in drug delivery and neuromodulation. Studies have revealed that low-intensity ultrasound can improve cognitive functions and have positive effects on senescent mice and Alzheimer's disease. These findings are important for accelerating the clinical application of low-intensity ultrasound.

BRAIN SCIENCES (2022)

添加到收藏夹
Article Clinical Neurology

Sonogenetics: Recent advances and future directions

Tianyi Liu et al.

Summary: This paper summarizes recent findings on sonogenetics, highlighting cleared technical hurdles, remaining challenges, and future directions for optimization.

BRAIN STIMULATION (2022)

添加到收藏夹
Article Chemistry, Multidisciplinary

Monodisperse magnetic lecithin-PFP submicron bubbles as dual imaging contrast agents for ultrasound (US) and MRI

Hira Waqar et al.

Summary: Magnetic microbubbles synthesized in this study showed a negative contrast effect in MRI and provided good contrast in ultrasound imaging at lower concentrations, with excellent hemocompatibility demonstrated. Optimization of concentration was necessary to achieve the best effect on both modalities.

RSC ADVANCES (2022)

添加到收藏夹
Review Oncology

Blood-brain barrier opening with low intensity pulsed ultrasound for immune modulation and immune therapeutic delivery to CNS tumors

Kevin Beccaria et al.

Summary: Pulsed low intensity ultrasound has been developed as a safe technique to open the blood-brain barrier (BBB) and enhance the delivery of immune therapeutics to the brain, showing promising results in preclinical and clinical studies for brain tumor treatment. Ultrasound-induced BBB disruption not only controls tumor growth but also stimulates immune responses.

JOURNAL OF NEURO-ONCOLOGY (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Functional gadolinium-based nanoscale systems for cancer theranostics

Haonan Li et al.

Summary: Cancer theranostics is a new strategy that combines cancer imaging and treatment through the use of Gd-based nanomaterials to enhance therapeutic efficacy and monitor the treatment process. This review discusses recent advances in Gd-based nanomaterials for cancer theranostics and provides perspectives on their potential in cancer treatment.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹
Article Nanoscience & Nanotechnology

Ultrasound-induced and MRI-monitored CuO nanoparticles release from micelle encapsulation

Roana N. Schiopu Aresteanu et al.

Summary: This study introduces a method for encapsulating and releasing CuO NPs using ultrasound-induced hyperthermia, monitored by MRI. Results showed that the encapsulated NPs were detectable by MRI T1 mapping, and ultrasonic hyperthermia stimulated the release of NPs, which was clearly visible in T1-weighted imaging.

NANOTECHNOLOGY (2021)

添加到收藏夹
Article Biophysics

Shaping the synthesis of surfactant-stabilized oxygen microbubbles to accommodate encapsulated drug

Purva B. Vaidya et al.

Summary: Oxygen filled microbubbles, SE61(O2), were developed for localized, ultrasound-triggered oxygen delivery to hypoxic tumors. A new fabrication method was developed to improve microbubble yield and encapsulation efficiency, resulting in greater stability and a more effective treatment approach.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

添加到收藏夹
Article Nanoscience & Nanotechnology

Genetically Engineered Bacterial Protein Nanoparticles for Targeted Cancer Therapy

Haiyan Yang et al.

Summary: The novel strategy of combining bacteriotherapy with HIFU therapy in this study showed significantly higher tumor inhibition rate up to 87% compared to monotherapies, providing a promising approach for more effective breast cancer treatment.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

添加到收藏夹
Article Oncology

Focused Ultrasound-Mediated Blood-Brain Barrier Opening Increases Delivery and Efficacy of Etoposide for Glioblastoma Treatment

Hong-Jian Wei et al.

Summary: Glioblastoma is a devastating disease with poor treatment outcomes. It has been found that using focused ultrasound to open the blood-brain barrier can enhance drug delivery, increasing etoposide concentration in the brain and leading to local control and survival benefits for tumors.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2021)

添加到收藏夹
Review Engineering, Biomedical

Another decade of photoacoustic imaging

Dhiman Das et al.

Summary: Photoacoustic imaging is a hybrid biomedical imaging modality that is rapidly advancing and finding its way to clinical practices. With improvements in technology, cost reduction, and increased portability, it holds great potential for a wide range of applications. The steady growth of the photoacoustic community and exploration of new directions by researchers suggest that photoacoustic imaging will establish itself as a regular imaging system in clinical practices in the future.

PHYSICS IN MEDICINE AND BIOLOGY (2021)

添加到收藏夹
Article Acoustics

LARGE-VOLUME HYPERTHERMIA FOR SAFE AND COST-EFFECTIVE TARGETED DRUG DELIVERY USING A CLINICAL ULTRASOUND-GUIDED FOCUSED ULTRASOUND DEVICE

Paul Christopher Lyon et al.

Summary: LTSLs are designed to release chemotherapy agents under mild hyperthermia conditions. By utilizing ultrasound-guided FUS systems, it is possible to rapidly induce and sustain mild hyperthermia in large tissue volumes, showing promise for successful application in drug delivery and cancer treatment.

ULTRASOUND IN MEDICINE AND BIOLOGY (2021)

添加到收藏夹
Article Pharmacology & Pharmacy

Ultrasound responsive self-assembled micelles loaded with hypocrellin for cancer sonodynamic therapy

Xuexue Liu et al.

Summary: Reactive oxygen species (ROS)-responsive micelles composed of poly (ethylene glycol)-poly(propylene sulfide) (PEG-PPS) can achieve targeted delivery and in situ release of drugs for cancer treatment, leading to effective growth inhibition through sonodynamic therapy (SDT).

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Theranostic nanobubbles towards smart nanomedicines

Mahsa Zahiri et al.

Summary: The development of gas system as a platform for fabricated nanobubbles has attracted interest in improving effectiveness of ultrasound therapy, diagnosis, and treatment in cancer patients. Nanobubbles, as ultrasound contrast agents, exhibit good stability and contrast enhancement capability, making them promising tools for cancer diagnosis and treatment.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹
Review Pharmacology & Pharmacy

Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J. Deprez et al.

Summary: Ultrasound, in addition to its clinical imaging application, has been extensively explored as a tool to enhance drug delivery. Therapeutic ultrasound can permeabilize biological barriers, enabling drugs to reach otherwise impermeable tissues and offering a new approach for drug delivery.

ADVANCED DRUG DELIVERY REVIEWS (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Enhanced Ultrasound Contrast of Renal-Clearable Luminescent Gold Nanoparticles

Yue Tan et al.

Summary: This study introduces ultrasmall renal-clearable luminescent gold nanoparticles with pH-induced charge reversal and aggregation properties, which enhance ultrasound contrast in injured kidneys through increased tubular reabsorption and in situ aggregation. The tuning elimination pathway of these nanoparticles provides a synergistical fluorescence and ultrasound imaging strategy for diagnosing early kidney injury with precise anatomical information.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹
Review Biochemical Research Methods

Recent nanotheranostics applications for cancer therapy and diagnosis: A review

Fahimeh Aminolroayaei et al.

Summary: Nanotheranostics has gained significant attention for its versatile applications in molecular imaging and cancer therapy, particularly in early cancer diagnosis. Each nanoparticle has its own advantages and limitations, requiring thorough examination before clinical applications. Recent advancements in nanotheranostics for cancer therapy and diagnosis, as well as its use as a contrast agent in various imaging modalities and a platform for cancer therapy, are explored in this review.

IET NANOBIOTECHNOLOGY (2021)

添加到收藏夹
Article Nanoscience & Nanotechnology

Acoustically triggered mechanotherapy using genetically encoded gas vesicles

Avinoam Bar-Zion et al.

Summary: Recent advancements in molecular engineering and synthetic biology have enabled the development of biomolecular and cell-based therapies with high molecular specificity, but limited spatiotemporal control. Gas vesicles, a genetically encodable air-filled protein nanostructure, can be engineered to deliver potent mechanical effects at specific locations inside the body through ultrasound-induced inertial cavitation. This capability has potential applications in remotely actuated cell-killing and tissue-disrupting agents, demonstrating the therapeutic potential of gas vesicles under focused ultrasound actuation.

NATURE NANOTECHNOLOGY (2021)

添加到收藏夹
Article Chemistry, Physical

Dendritic organosilica nanospheres with large mesopores as multi-guests vehicle for photoacoustic/ultrasound imaging-guided photodynamic therapy

Yuting Huang et al.

Summary: The study introduces a novel photodynamic therapy strategy using dendritic mesoporous organosilica nanoparticles (MONs) encapsulated with indocyanine green and catalase to overcome tumor hypoxia, effectively killing cancer cells and realizing multimodal image-guided therapy.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Exosome-based photoacoustic imaging guided photodynamic and immunotherapy for the treatment of pancreatic cancer

Yongho Jang et al.

Summary: In this study, tumor-derived reassembled exosome (R-Exo) was used both as a drug delivery carrier and an immunostimulatory agent for cancer therapy. By loading chlorin e6 photosensitizer into R-Exo, it retained its original size and membrane proteins for targeting tumor cells. The modified exosomes were able to generate reactive oxygen species and increase cytokine release from immune cells, showing their potential as an immunotherapeutic agent.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹
Article Nanoscience & Nanotechnology

Therapeutic efficacy and cardioprotection of nucleolin-targeted doxorubicin-loaded ultrasound nanobubbles in treating triple-negative breast cancer

Kejing Fang et al.

Summary: The AS1411-DOX-NBs showed enhanced tumour cell-killing ability in vitro by increasing the active uptake of drugs, and significantly inhibited the growth of TNBC xenografts while maintaining the weight and health of the mice. Echocardiography and pathological examination confirmed that AS1411-DOX-NBs effectively induced tumour tissue apoptosis and necrosis while reducing DOX-induced cardiotoxicity.

NANOTECHNOLOGY (2021)

添加到收藏夹
Article Acoustics

FOCUSED ULTRASOUND AND MICROBUBBLE TREATMENT INCREASES DELIVERY OF TRANSFERRIN RECEPTOR-TARGETING LIPOSOMES TO THE BRAIN

Marieke Olsman et al.

Summary: Research shows that combining FUS and microbubbles with BBB-targeting liposomes can enhance drug delivery to the brain. Transferrin receptor-targeting liposomes exhibited increased accumulation in the FUS-treated hemisphere, while isotype immunoglobulin G liposomes did not show significant increase.

ULTRASOUND IN MEDICINE AND BIOLOGY (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

A Robust Oxygen Microbubble Radiosensitizer for Iodine-125 Brachytherapy

Sheng Peng et al.

Summary: This study aims to sensitize hypoxic areas in solid tumors by utilizing ultrasound-activated oxygen microbubbles for I-125 brachytherapy. The developed O-2/SF6 microbubbles have shown a longer half-life and greatly improved therapeutic efficacy in hypoxic tumors compared to brachytherapy alone in mouse models.

ADVANCED SCIENCE (2021)

添加到收藏夹
Article Engineering, Biomedical

Image-guided thermosensitive liposomes for focused ultrasound enhanced co-delivery of carboplatin and SN-38 against triple negative breast cancer in mice

Paul Cressey et al.

Summary: Triggerable nanocarriers have the potential to improve the therapeutic index of existing anticancer agents by enabling localized delivery and release of therapeutic cargos. In this study, the first co-delivery of SN-38 and carboplatin was achieved using an MRI-visible thermosensitive liposome, showing both thermosensitivity and MR-imageability. The co-delivery resulted in significant improvements in anti-tumor activity in triple negative breast cancer xenografts tumors in mice.

BIOMATERIALS (2021)

添加到收藏夹
Article Acoustics

Multifocused Ultrasound Therapy for Controlled Microvascular Permeabilization and Improved Drug Delivery

Lokesh Basavarajappa et al.

Summary: The study investigated various multi-focused ultrasound (FUS) strategies for enhancing microvascular permeability in cancer therapy. Results showed that multi-FUS with temporal sequential excitation (multi-FUS-TSE) group exhibited significantly higher intratumoral dye accumulation and fluorescence measurements compared to other therapy groups. This demonstrates that the spatial and temporal aspects of FUS therapy play a crucial role in increasing microvascular permeability.

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL (2021)

添加到收藏夹
Article Nanoscience & Nanotechnology

In vivo Multi-scale Photoacoustic Imaging Guided Photothermal Therapy of Cervical Cancer based on Customized Laser System and Targeted Nanoparticles

Ting Qiu et al.

Summary: The combination of photoacoustic imaging and photothermal therapy systems with novel PD-FA nanoparticles provides a powerful tool for the early diagnosis and precise treatment of cervical cancer.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

添加到收藏夹
Review Pharmacology & Pharmacy

Design of liposomes as drug delivery system for therapeutic applications

Diana Guimaraes et al.

Summary: Liposomes are effective drug delivery systems that improve therapeutic efficacy, being nontoxic and biodegradable. Key aspects such as design, production techniques, drug loading, and characterization for in vitro and in vivo performance are essential for successful liposomal formulations. Other topics explored include functionalization, targeting strategies, stability, limitations, and current market applications of liposomes in various therapeutic fields.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Polymeric micelles in cancer therapy: State of the art

Balaram Ghosh et al.

Summary: Polymeric micelles are extensively used for delivering poorly soluble chemotherapeutic agents in cancer treatment. These micelles can be easily tailored by self-assembly of amphiphilic polymers to optimize drug loading, stability, and delivery to target tissues. The current trend focuses on developing various block polymeric micelles and stimuli-sensitive micelles to enhance therapeutic activity.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹
Article Medicine, Research & Experimental

Combining Mechanical High-Intensity Focused Ultrasound Ablation with Chemotherapy for Augmentation of Anticancer Immune Responses

Chao Li et al.

Summary: Combining HIFU with nanodroplets showed enhanced anticancer efficacy by triggering anticancer immune responses, inducing immunogenic cell death, activating DCs maturation, and enhancing effector T-cell infiltration within tumors.

MOLECULAR PHARMACEUTICS (2021)

添加到收藏夹
Article Acoustics

Ultrasound responsive carbon monoxide releasing micelle

Osamah Alghazwat et al.

Summary: A study developed an ultrasound responsive micelle for localized CO delivery, demonstrating its significant therapeutic effects in prostate cancer cells.

ULTRASONICS SONOCHEMISTRY (2021)

添加到收藏夹
Article Acoustics

Tailoring the size of ultrasound responsive lipid-shelled nanodroplets by varying production parameters and environmental conditions

Sara Ferri et al.

Summary: The study showed that during the preparation of NDs, factors such as PFP concentration, sonication power and duration, and the addition of a lipophilic fluorescent dye can affect the size and distribution of NDs. NDs exhibited different stability under various conditions, and phase transition may occur at 37℃.

ULTRASONICS SONOCHEMISTRY (2021)

添加到收藏夹
Article Biotechnology & Applied Microbiology

Ultrasound targeted microbubble destruction combined with Fe-MOF based bio-/enzyme-mimics nanoparticles for treating of cancer

Xi Xiang et al.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

添加到收藏夹
Article Instruments & Instrumentation

Ultrasound-responsive polymer-based drug delivery systems

Ping Wei et al.

Summary: Ultrasound-responsive polymeric materials have shown great potential for efficient drug delivery and targeted treatment in various biomedical applications, including tumor therapy and disruption of the blood-brain barrier. Future research directions for the development of these smart materials are also discussed to facilitate clinical translation.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2021)

添加到收藏夹
Article Engineering, Biomedical

Gas-filled protein nanostructures as cavitation nuclei for molecule-specific sonodynamic therapy

Lin Song et al.

Summary: Sonodynamic therapy (SDT) utilizing gas vesicles (GVs) as stable nuclei enhances cavitation effects, increases cell toxicity, and exhibits specific targeting towards CD44(+) cells.

ACTA BIOMATERIALIA (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Engineering Janus Chemoreactive Nanosonosensitizers for Bilaterally Augmented Sonodynamic and Chemodynamic Cancer Nanotherapy

Wenwen Xu et al.

Summary: In this study, a TiO2-Fe3O4@PEG Janus nanostructure was designed and engineered for bilaterally enhanced SDT and CDT. The rational design not only improved the treatment efficacy but also addressed the major concerns of SDT, providing a promising approach for non-invasive therapy.

ADVANCED FUNCTIONAL MATERIALS (2021)

添加到收藏夹
Article Engineering, Biomedical

Molecular magnetic resonance imaging of Alpha-v-Beta-3 integrin expression in tumors with ultrasound microbubbles

Vertika Pathak et al.

Summary: This study investigated the use of microbubbles containing superparamagnetic iron oxide nanoparticles as molecular MRI contrast agents targeted against angiogenesis in breast cancer. Results indicated that RGD-SPION-MB showed higher retention in angiogenic vessels compared to SPION-MB and RAD-SPION-MB, demonstrating their potential as effective molecular MR/US contrast agents for assessing integrin expression in neovasculature.

BIOMATERIALS (2021)

添加到收藏夹
Article Pharmacology & Pharmacy

Synthesis of a gemcitabine-modified phospholipid and its subsequent incorporation into a single microbubble formulation loaded with paclitaxel for the treatment of pancreatic cancer using ultrasound-targeted microbubble destruction

Keiran A. Logan et al.

Summary: The study demonstrates the successful synthesis of gemcitabine-functionalized lipid for stable microbubble formulations, showing significant reduction in cell viability in pancreatic cancer models and improved tumor growth delay. These results suggest the potential of gemcitabine/paclitaxel-mediated ultrasound targeted microbubble destruction as a promising treatment for pancreatic cancer.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2021)

添加到收藏夹
Article Nanoscience & Nanotechnology

iRGD Peptide-Mediated Liposomal Nanoparticles with Photoacoustic/Ultrasound Dual-Modality Imaging for Precision Theranostics Against Hepatocellular Carcinoma

Huipu Li et al.

Summary: A novel molecular probe was successfully prepared for precision theranostics against hepatocellular carcinoma (HCC), which can perform ultrasound/photoacoustic dual-modality imaging and penetrate deep into tumors for better therapeutic effects.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

添加到收藏夹
Article Cell Biology

In vivo visualization and characterization of inflamed intestinal wall: the exploration of targeted microbubbles in assessing NF-κB expression

Chenyang Zhao et al.

Summary: NF-kappa B, a critical cytokine in inflammatory bowel diseases (IBD), can be accurately detected and quantified on the intestinal walls of IBD using NF-kappa B-targeted microbubbles and molecular contrast-enhanced ultrasound.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

添加到收藏夹
Review Biochemistry & Molecular Biology

Forward Precision Medicine: Micelles for Active Targeting Driven by Peptides

Filippo Prencipe et al.

Summary: Precision medicine relies on innovative management methods for active components, delivering drugs to specific tissues to enhance therapeutic effects and reduce side effects. Utilizing drug-encapsulated micelles for active targeting marks a new frontier in precision medicine. By decorating micelles with targeting bioactive moieties like peptides, it is possible to direct drugs towards a range of molecular targets, particularly on cancer cells and vasculature.

MOLECULES (2021)

添加到收藏夹
Editorial Material Biotechnology & Applied Microbiology

Polymeric micelles as drug delivery systems in cancer: challenges and opportunities

Swati Biswas

Summary: Micelles serve as nanocarriers for hydrophobic chemotherapeutic drugs, with promising potential for clinical translation based on current preclinical research findings.

NANOMEDICINE (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

NIR-II Excitation Phototheranostic Nanomedicine for Fluorescence/Photoacoustic Tumor Imaging and Targeted Photothermal-Photonic Thermodynamic Therapy

Yeneng Dai et al.

Summary: This study presents a second near infrared light excitation phototheranostic nanomedicine for the treatment of triple-negative breast cancer, integrating multiple functional components for precise diagnosis and effective therapy through targeting, localization, and multimodal imaging.

SMALL (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Organic Sonosensitizers for Sonodynamic Therapy: From Small Molecules and Nanoparticles toward Clinical Development

Dong Li et al.

Summary: Sonodynamic therapy (SDT) is a novel noninvasive therapeutic approach that combines low-intensity ultrasound with sonosensitizers. Compared to phototherapy, SDT offers advantages such as deeper tissue penetration, high accuracy, and reduced side effects. The use of organic sonosensitizers is crucial for therapeutic efficacy, and nanotechnology holds potential for overcoming obstacles and fostering innovation in this field.

SMALL (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

All-in-One Zeolite-Carbon-Based Nanotheranostics with Adjustable NIR-II Window Photoacoustic/Fluorescence Imaging Performance for Precise NIR-II Photothermal-Synergized Catalytic Antitumor Therapy

Ziliang Zheng et al.

Summary: This study introduces a novel nanozyme HSC-2 with excellent dual-mode NIR-II PA/NIR-II FL imaging performance for precise photothermal-catalytic synergistic therapy. Through optimizing the silicon-to-carbon ratio, HSC-2 achieves efficient tumor photothermal therapy in the NIR-II window and exhibits remarkable synergistic therapeutic effects in the tumor microenvironment.

SMALL (2021)

添加到收藏夹
Article Multidisciplinary Sciences

Transferrin-modified liposomes triggered with ultrasound to treat HeLa cells

Nour M. AlSawaftah et al.

Summary: Targeted liposomes triggered with ultrasound enable controlled drug release and reduce side effects. Transferrin-conjugated pegylated liposomes are more sensitive to ultrasound and exhibit higher drug uptake ability.

SCIENTIFIC REPORTS (2021)

添加到收藏夹
Article Chemistry, Multidisciplinary

Precise Ultrasound Neuromodulation in a Deep Brain Region Using Nano Gas Vesicles as Actuators

Xuandi Hou et al.

Summary: Ultrasound can be used non-invasively for neuromodulation, with the potential to improve spatial resolution and increase effectiveness. A neurostimulation scheme using gas vesicles as actuators showed enhanced and targeted effects without significant cytotoxicity, demonstrating a promising method for improved neurostimulation.

ADVANCED SCIENCE (2021)

添加到收藏夹
Review Oncology

Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery

T. A. Arsiwala et al.

Summary: The blood-brain barrier (BBB) serves as a major barrier limiting drug passage into the brain, while the blood-tumor barrier (BTB) forms around tumors and remains effective in preventing chemotherapy delivery. Focused ultrasound is a noninvasive technique that can disrupt the BBB transiently, aiding in increased drug accumulation within targeted brain areas.

NEOPLASIA (2021)

添加到收藏夹
Article Pharmacology & Pharmacy

Targeted Delivery of Liposomal Temozolomide Enhanced Anti-Glioblastoma Efficacy through Ultrasound-Mediated Blood-Brain Barrier Opening

Zhuqing Song et al.

Summary: The ultrasound-mediated BBB opening combined with liposomal temozolomide formulation has been successfully applied in the treatment of glioblastoma, significantly inhibiting tumor growth and prolonging animal survival time without significant side effects.

PHARMACEUTICS (2021)

添加到收藏夹
Article Pharmacology & Pharmacy

Ultrasound-Mediated Blood-Brain Barrier Opening Improves Whole Brain Gene Delivery in Mice

Marie-Solenne Felix et al.

Summary: Gene therapy is a powerful tool for treating diseased tissues and providing lasting and effective correction. The combination of focused ultrasound and microbubbles appears to be a technological breakthrough for delivering therapeutic agents to the central nervous system.

PHARMACEUTICS (2021)

添加到收藏夹
Article Radiology, Nuclear Medicine & Medical Imaging

MR-guided blood-brain barrier opening induced by rapid short-pulse ultrasound in non-human primates

Hui Zhou et al.

Summary: The study aimed to test the feasibility and safety of opening the BBB in a nonhuman primate model using RaSP ultrasound sequence and MBs. The results showed successful BBB opening with RaSP, indicating it as a practical method in large animal models.

QUANTITATIVE IMAGING IN MEDICINE AND SURGERY (2021)

添加到收藏夹
Article Materials Science, Biomaterials

Hybrid theranostic microbubbles for ultrasound/photoacoustic imaging guided starvation/low-temperature photothermal/hypoxia-activated synergistic cancer therapy

Feng Tian et al.

Summary: Development of a hybrid microbubble-based theranostic platform for high-contrast multimodality imaging-guided synergistic tumor therapy, combining starvation therapy, low-temperature photothermal therapy, and hypoxia-activated therapy. The platform showed long-term tumor retention and minimal systemic side effects, inhibiting solid tumor growth effectively through dual-modality ultrasound and enhanced photoacoustic imaging.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Advanced biotechnology-assisted precise sonodynamic therapy

Yi Zhang et al.

Summary: The article discusses the advantages and potential of photodynamic therapy and sonodynamic therapy in the treatment of deep-seated tumors, as well as imaging-guided precise SDT and recent clinical trials. It also summarizes the strategies for designing sonosensitizers based on tumor environment and structure modifications, as well as the approach of SDT combination therapy.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹
Article Oncology

Real-Time US-CT fusion imaging for guidance of thermal ablation in of renal tumors invisible or poorly visible with US: results in 97 cases

Giovanni Mauri et al.

Summary: The study evaluated the use of ultrasound-computed tomography fusion imaging for precise targeting of renal tumors poorly visible or invisible with ultrasound. It was found to be technically feasible with a high rate of success and efficacy in tumor targeting.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Current advances in ultrasound-combined nanobubbles for cancer-targeted therapy: a review of the current status and future perspectives

Chunhong Su et al.

Summary: This review explores the advances in ultrasound-nanobubble combined strategies for targeted cancer treatment. It discusses the composition and formulation parameters of NBs, interactions and biological effects of combining NBs and ultrasound, and the potential of NBs combined with US for targeted cancer therapeutics. The review also proposes present and future directions for improving current methods in this field.

RSC ADVANCES (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Recent advances in nanomaterial-based augmented sonodynamic therapy of cancer

Wooram Um et al.

Summary: Sonodynamic therapy (SDT) has emerged as a promising alternative to conventional cancer therapies due to its safety and cost-effectiveness. However, the insufficient reactive oxygen species (ROS) production of current sonosensitizers has hindered its clinical application. Recent nanomaterial-based SDT strategies aim to improve sonosensitizer efficiency and enhance oxidative stress for potential anti-tumor immunity.

CHEMICAL COMMUNICATIONS (2021)

添加到收藏夹
Article Medicine, Research & Experimental

Ultrasound-mediated augmented exosome release from astrocytes alleviates amyloid-beta-induced neurotoxicity

Zhiting Deng et al.

Summary: The study showed that ultrasound stimulation can enhance the release of exosomes from astrocytes, which have neuroprotective effects against Aβ toxicity. When combined with ultrasound-induced blood-brain-barrier opening, it enables the clearance of Aβ plaques in the brain.

THERANOSTICS (2021)

添加到收藏夹
Review Chemistry, Multidisciplinary

Ultrasound-Activated Sensitizers and Applications

Xiahui Lin et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹
Review Oncology

Ultrasound nanotheranostics in fighting cancer: Advances and prospects

Li-Qiang Zhou et al.

CANCER LETTERS (2020)

添加到收藏夹
Article Cardiac & Cardiovascular Systems

Precise treatment of acute antibody -mediated cardiac allograft rejection in rats using C4d-targeted microbubbles loaded with nitric oxide

Tao Liao et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2020)

添加到收藏夹
Article Chemistry, Multidisciplinary

Carbon Nitride Hollow Theranostic Nanoregulators Executing Laser-Activatable Water Splitting for Enhanced Ultrasound/Fluorescence Imaging and Cooperative Phototherapy

Xing Zhang et al.

ACS NANO (2020)

添加到收藏夹
Article Chemistry, Multidisciplinary

Realizing Cancer Precision Medicine by Integrating Systems Biology and Nanomaterial Engineering

Jae Il Joo et al.

ADVANCED MATERIALS (2020)

添加到收藏夹
Article Chemistry, Multidisciplinary

A Nanostrategy for Efficient Imaging-Guided Antitumor Therapy through a Stimuli-Responsive Branched Polymeric Prodrug

Hao Cai et al.

ADVANCED SCIENCE (2020)

添加到收藏夹
Article Nanoscience & Nanotechnology

Ultrasound Mediated Destruction of LMW-HA-Loaded and Folate-Conjugated Nanobubble for TAM Targeting and Reeducation

Xiao Sun et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

添加到收藏夹
Article Oncology

Ultrasound-mediated nanobubble destruction (UMND) facilitates the delivery of VEGFR2-targeted CD-TK-loaded cationic nanobubbles in the treatment of bladder cancer

Cong Hu et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2020)

添加到收藏夹
Review Acoustics

THREE DECADES OF ULTRASOUND CONTRAST AGENTS: A REVIEW OF THE PAST, PRESENT AND FUTURE IMPROVEMENTS

Peter Frinking et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2020)

添加到收藏夹
Review Pharmacology & Pharmacy

Lipid-based microbubbles and ultrasound for therapeutic application

Daiki Omata et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

添加到收藏夹
Article Biochemical Research Methods

Ultrasound-Augmented Phase Transition Nanobubbles for Targeted Treatment of Paclitaxel-Resistant Cancer

Yi Zhu et al.

BIOCONJUGATE CHEMISTRY (2020)

添加到收藏夹
Article Biochemistry & Molecular Biology

Structure of LINC00511-siRNA-conjugated nanobubbles and improvement of cisplatin sensitivity on triple negative breast cancer

Bolin Wu et al.

FASEB JOURNAL (2020)

添加到收藏夹
Review Materials Science, Biomaterials

Ultrasound-Responsive Carriers for Therapeutic Applications

Rajeet Chandan et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

添加到收藏夹
Article Chemistry, Multidisciplinary

Biomolecular Ultrasound Imaging of Phagolysosomal Function

Bill Ling et al.

ACS NANO (2020)

添加到收藏夹
Review Chemistry, Multidisciplinary

Recent Advances in Nanomaterial-Assisted Combinational Sonodynamic Cancer Therapy

Shuang Liang et al.

ADVANCED MATERIALS (2020)

添加到收藏夹
Article Biochemistry & Molecular Biology

The tumor microenvironment

Nicole M. Anderson et al.

CURRENT BIOLOGY (2020)

添加到收藏夹
Review Acoustics

MICROBUBBLE AGENTS: NEW DIRECTIONS

Eleanor Stride et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2020)

添加到收藏夹
Review Chemistry, Multidisciplinary

Ultrasound and microbubble mediated therapeutic delivery: Underlying mechanisms and future outlook

Sayan Mullick Chowdhury et al.

JOURNAL OF CONTROLLED RELEASE (2020)

添加到收藏夹
Article Biotechnology & Applied Microbiology

Tri-modal imaging of gold-dotted magnetic nanoparticles for magnetic resonance imaging, computed tomography and intravascular ultrasound: an in vitro study

Joel Kuhn et al.

NANOMEDICINE (2020)

添加到收藏夹
Article Acoustics

Mechanisms underlying sonoporation: Interaction between microbubbles and cells

Yanye Yang et al.

ULTRASONICS SONOCHEMISTRY (2020)

添加到收藏夹
Article Biotechnology & Applied Microbiology

Multifunctional nanobubbles carrying indocyanine green and paclitaxel for molecular imaging and the treatment of prostate cancer

Minmin Lan et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

添加到收藏夹
Review Pharmacology & Pharmacy

Microbubbles and Nanobubbles with Ultrasound for Systemic Gene Delivery

Yoko Endo-Takahashi et al.

PHARMACEUTICS (2020)

添加到收藏夹
Article Multidisciplinary Sciences

Focused Ultrasound Induced Blood-Brain Barrier Opening for Targeting Brain Structures and Evaluating Chemogenetic Neuromodulation

Jerzy O. Szablowski et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2020)

添加到收藏夹
Review Oncology

Current Perspectives on Clinical Use of Exosomes as a Personalized Contrast Media and Theranostics

Tomasz Lorenc et al.

CANCERS (2020)

添加到收藏夹
Review Computer Science, Interdisciplinary Applications

Recent advances in applications of multimodal ultrasound-guided photoacoustic imaging technology

Shanshan Wang et al.

VISUAL COMPUTING FOR INDUSTRY BIOMEDICINE AND ART (2020)

添加到收藏夹
Article Nanoscience & Nanotechnology

Magnetic Resonance Imaging-Guided Focused Ultrasound-Based Delivery of Radiolabeled Copper Nanoclusters to Diffuse Intrinsic Pontine Glioma

Xiaohui Zhang et al.

ACS APPLIED NANO MATERIALS (2020)

添加到收藏夹
Article Materials Science, Biomaterials

A thermosensitive nanoplatform for photoacoustic imaging and NIR light triggered chemo-photothermal therapy

Zikang Chen et al.

BIOMATERIALS SCIENCE (2020)

添加到收藏夹
Review Oncology

The blood-brain barrier and blood-tumour barrier in brain tumours and metastases

Costas D. Arvanitis et al.

NATURE REVIEWS CANCER (2020)

添加到收藏夹
Review Chemistry, Multidisciplinary

Multifunctional sonosensitizers in sonodynamic cancer therapy

Subin Son et al.

CHEMICAL SOCIETY REVIEWS (2020)

添加到收藏夹
Article Chemistry, Physical

Rational Design of Inflammation-Responsive Inflatable Nanogels for Ultrasound Molecular Imaging

Jeongyun Heo et al.

CHEMISTRY OF MATERIALS (2019)

添加到收藏夹
Article Biophysics

Ultrasound triggered phase-change nanodroplets for doxorubicin prodrug delivery and ultrasound diagnosis: An in vitro study

Jinbiao Gao et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Chemotherapy sensitization of glioblastoma by focused ultrasound-mediated delivery of therapeutic liposomes

Alexandros Papachristodoulou et al.

JOURNAL OF CONTROLLED RELEASE (2019)

添加到收藏夹
Article Engineering, Biomedical

Ultrasound/Acidity-Triggered and Nanoparticle-Enabled Analgesia

Xiong Gao et al.

ADVANCED HEALTHCARE MATERIALS (2019)

添加到收藏夹
Article Chemistry, Medicinal

Enhancing Tumor Drug Distribution With Ultrasound-Triggered Nanobubbles

Pinunta Nittayacharn et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

添加到收藏夹
Article Acoustics

Breast Cancer Brain Metastasis Response to Radiation After Microbubble Oxygen Delivery in a Murine Model

Lauren J. Delaney et al.

JOURNAL OF ULTRASOUND IN MEDICINE (2019)

添加到收藏夹
Article Medicine, Research & Experimental

Enhancing Nab-Paclitaxel Delivery Using Microbubble-Assisted Ultrasound in a Pancreatic Cancer Model

Diane Bressand et al.

MOLECULAR PHARMACEUTICS (2019)

添加到收藏夹
Article Biotechnology & Applied Microbiology

Ultrasound-microbubbles-mediated microRNA-449a inhibits lung cancer cell growth via the regulation of Notch 1

Lingwu Meng et al.

ONCOTARGETS AND THERAPY (2019)

添加到收藏夹
Article Engineering, Biomedical

Sonoprinting of nanoparticle-loaded microbubbles: Unraveling the multi-timescale mechanism

Silke Roovers et al.

BIOMATERIALS (2019)

添加到收藏夹
Article Nanoscience & Nanotechnology

Preparation Of Nanobubbles Modified With A Small-Molecule CXCR4 Antagonist For Targeted Drug Delivery To Tumors And Enhanced Ultrasound Molecular Imaging

Yanli Peng et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

添加到收藏夹
Article Nanoscience & Nanotechnology

Echogenic PEGylated PEI-Loaded Microbubble As Efficient Gene Delivery System

Chun Liufu et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

添加到收藏夹
Article Biochemistry & Molecular Biology

Sinoporphyrin sodium based sonodynamic therapy induces anti-tumor effects in hepatocellular carcinoma and activates p53/caspase 3 axis

Enze Li et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

The Role of Ultrasound-Driven Microbubble Dynamics in Drug Delivery: From Microbubble Fundamentals to Clinical Translation

Silke Roovers et al.

LANGMUIR (2019)

添加到收藏夹
Article Nanoscience & Nanotechnology

Biocompatible Chitosan Nanobubbles for Ultrasound-Mediated Targeted Delivery of Doxorubicin

Xiaoying Zhou et al.

NANOSCALE RESEARCH LETTERS (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound

S. Roovers et al.

JOURNAL OF CONTROLLED RELEASE (2019)

添加到收藏夹
Article Engineering, Biomedical

Passive acoustic mapping of extravasation following ultrasound-enhanced drug delivery

Catherine Paverd et al.

PHYSICS IN MEDICINE AND BIOLOGY (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Surface Composition and Preparation Method for Oxygen Nanobubbles for Drug Delivery and Ultrasound Imaging Applications

Muhammad Saad Khan et al.

NANOMATERIALS (2019)

添加到收藏夹
Review Acoustics

A review of clinical photoacoustic imaging: Current and future trends

Amalina Binte Ebrahim Attia et al.

PHOTOACOUSTICS (2019)

添加到收藏夹
Article Medicine, Research & Experimental

Normalization of Tumor Vasculature by Oxygen Microbubbles with Ultrasound

Yi-Ju Ho et al.

THERANOSTICS (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Gas-generating nanoparticles for contrast-enhanced ultrasound imaging

In-Cheol Sun et al.

NANOSCALE (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Ultrasound-controlled DOX-SiO2 nanocomposites enhance the antitumour efficacy and attenuate the toxicity of doxorubicin

Yin Wang et al.

NANOSCALE (2019)

添加到收藏夹
Article Medicine, Research & Experimental

Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy

Eloise Thomas et al.

THERANOSTICS (2019)

添加到收藏夹
Article Chemistry, Multidisciplinary

Size-Modulable Nanoprobe for High-Performance Ultrasound Imaging and Drug Delivery against Cancer

Lu Zhang et al.

ACS NANO (2018)

添加到收藏夹
Article Biochemistry & Molecular Biology

Sono-photodynamic modality for cancer treatment using biodegradable bio-conjugated sonnelux nanocomposite in tumor-bearing mice: Activated cancer therapy using light and ultrasound

Samir Ali Abd El-Kaream et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

添加到收藏夹
Article Oncology

Targeted shRNA-loaded liposome complex combined with focused ultrasound for blood brain barrier disruption and suppressing glioma growth

Guanjian Zhao et al.

CANCER LETTERS (2018)

添加到收藏夹
Article Oncology

Sonodynamic therapy-assisted immunotherapy: A novel modality for cancer treatment

Qianyu Zhang et al.

CANCER SCIENCE (2018)

添加到收藏夹
Review Nanoscience & Nanotechnology

Stimuli-responsive polymeric micelles for drug delivery and cancer therapy

Qing Zhou et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

添加到收藏夹
Article Cell Biology

Mechanisms of enhanced antiglioma efficacy of polysorbate 80-modified paclitaxel-loaded PLGA nanoparticles by focused ultrasound

Yingjia Li et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)

添加到收藏夹
Article Biochemistry & Molecular Biology

Ultrasound-triggered effects of the microbubbles coupled to GDNF- and Nurr1-loaded PEGylated liposomes in a rat model of Parkinson's disease

Peijian Yue et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

添加到收藏夹
Review Chemistry, Multidisciplinary

Mechanistic understanding the bioeffects of ultrasound-driven microbubbles to enhance macromolecule delivery

Peng Qin et al.

JOURNAL OF CONTROLLED RELEASE (2018)

添加到收藏夹
Article Chemistry, Multidisciplinary

Focused ultrasound-enabled delivery of radiolabeled nanoclusters to the pons

Dezhuang Ye et al.

JOURNAL OF CONTROLLED RELEASE (2018)

添加到收藏夹
Article Chemistry, Multidisciplinary

US-detonated nano bombs facilitate targeting treatment of resistant breast cancer

Jinjin Shi et al.

JOURNAL OF CONTROLLED RELEASE (2018)

添加到收藏夹
Article Pharmacology & Pharmacy

Ultrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial Cells

Peng-Fei Sun et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2018)

添加到收藏夹
Article Multidisciplinary Sciences

Ultrasound-mediated delivery and distribution of polymeric nanoparticles in the normal brain parenchyma of a metastatic brain tumour model

Habib Baghirov et al.

PLOS ONE (2018)

添加到收藏夹
Review Biology

Sonodynamic therapy (SDT): a novel strategy for cancer nanotheranostics

Xueting Pan et al.

SCIENCE CHINA-LIFE SCIENCES (2018)

添加到收藏夹
Article Multidisciplinary Sciences

Blood-brain barrier opening in Alzheimer's disease using MR-guided focused ultrasound

Nir Lipsman et al.

NATURE COMMUNICATIONS (2018)

添加到收藏夹
Article Medicine, Research & Experimental

Cell-penetrating Peptide-modified Targeted Drug-loaded Phase-transformation Lipid Nanoparticles Combined with Low-intensity Focused Ultrasound for Precision Theranostics against Hepatocellular Carcinoma

Hongyun Zhao et al.

THERANOSTICS (2018)

添加到收藏夹
Article Engineering, Biomedical

Gas-Stabilizing Gold Nanocones for Acoustically Mediated Drug Delivery

Christophoros Mannaris et al.

ADVANCED HEALTHCARE MATERIALS (2018)

添加到收藏夹
Article Radiology, Nuclear Medicine & Medical Imaging

Imaging with ultrasound contrast agents: current status and future

Wui K. Chong et al.

ABDOMINAL RADIOLOGY (2018)

添加到收藏夹
Article Biochemistry & Molecular Biology

Nucleus-Targeted, Echogenic Polymersomes for Delivering a Cancer Sternness Inhibitor to Pancreatic Cancer Cells

Fataneh Karandish et al.

BIOMACROMOLECULES (2018)

添加到收藏夹
Article Medicine, Research & Experimental

Ultrasound Microbubble Delivery Targeting Intraplaque Neovascularization Inhibits Atherosclerotic Plaque in an APOE-deficient Mouse Model

Hong Yuan et al.

IN VIVO (2018)

添加到收藏夹
Article Chemistry, Multidisciplinary

Enhanced drug delivery using sonoactivatable liposomes with membrane-embedded porphyrins

Xiaobing Wang et al.

JOURNAL OF CONTROLLED RELEASE (2018)

添加到收藏夹
Article Chemistry, Multidisciplinary

pH and Ultrasound Dual-Responsive Polydopamine-Coated Mesoporous Silica Nanoparticles for Controlled Drug Delivery

Xiaochong Li et al.

LANGMUIR (2018)

添加到收藏夹
Article Nanoscience & Nanotechnology

Clinical ultrasound stimulating angiogenesis following drug-release from polymersomes on the ischemic zone for peripheral arterial occlusive disease

Chung-Dann Kan et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

添加到收藏夹
Article Materials Science, Multidisciplinary

Ultrasound contrast agent microbubbles with ultrahigh loading capacity of camptothecin and floxuridine for enhancing tumor accumulation and combined chemotherapeutic efficacy

Xiaolong Liang et al.

NPG ASIA MATERIALS (2018)

添加到收藏夹
Article Oncology

Insonation of Systemically Delivered Cisplatin-Loaded Microbubbles Significantly Attenuates Nephrotoxicity of Chemotherapy in Experimental Models of Head and Neck Cancer

Hang-Kang Chen et al.

CANCERS (2018)

添加到收藏夹
Article Nanoscience & Nanotechnology

Triple-Modal Imaging-Guided Chemo-Photothermal Synergistic Therapy for Breast Cancer with Magnetically Targeted Phase-Shifted Nanoparticles

Long Wang et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

添加到收藏夹
Article Acoustics

Blood-BrainBarrier Closure TimeAfter Controlled Ultrasound-Induced Opening Is Independent of Opening Volume

Meaghan A. O'Reilly et al.

JOURNAL OF ULTRASOUND IN MEDICINE (2017)

添加到收藏夹
Article Medicine, Research & Experimental

Drug Delivery from a Multi-faceted Ultrasound Contrast Agent: Influence of Shell Composition

Lauren J. Jablonowski et al.

MOLECULAR PHARMACEUTICS (2017)

添加到收藏夹
Article Engineering, Biomedical

Ultrasound-triggered local anaesthesia

Alina Y. Rwei et al.

NATURE BIOMEDICAL ENGINEERING (2017)

添加到收藏夹
Article Chemistry, Inorganic & Nuclear

An enhanced chemotherapeutic effect facilitated by sonication of MSN

Yi Ding et al.

DALTON TRANSACTIONS (2017)

添加到收藏夹
Article Cell & Tissue Engineering

Magnetic Enhancement of Stem Cell-Targeted Delivery into the Brain Following MR-Guided Focused Ultrasound for Opening the Blood-Brain Barrier

Wei-Bin Shen et al.

CELL TRANSPLANTATION (2017)

添加到收藏夹
Review Chemistry, Multidisciplinary

Micro/Nanoparticle-Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation

Xiaoqin Qian et al.

ADVANCED MATERIALS (2016)

添加到收藏夹
Article Engineering, Biomedical

Sonoprinting and the importance of microbubble loading for the ultrasound mediated cellular delivery of nanoparticles

Ine De Cock et al.

BIOMATERIALS (2016)

添加到收藏夹
Article Biochemical Research Methods

In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications

Guillaume Lajoinie et al.

BIOMICROFLUIDICS (2016)

添加到收藏夹
Article Multidisciplinary Sciences

Biophysical insight into mechanisms of sonoporation

Brandon Helfield et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

添加到收藏夹
Article Chemistry, Multidisciplinary

Polymer-Grafted Mesoporous Silica Nanoparticles as Ultrasound-Responsive Drug Carriers

Juan L. Paris et al.

ACS NANO (2015)

添加到收藏夹
Article Oncology

Treating cancer with sonodynamic therapy: A review

David Costley et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2015)

添加到收藏夹
Article Chemistry, Multidisciplinary

Ultrasound and microbubble mediated drug delivery: Acoustic pressure as determinant for uptake via membrane pores or endocytosis

Ine De Cock et al.

JOURNAL OF CONTROLLED RELEASE (2015)

添加到收藏夹
Review Chemistry, Multidisciplinary

Therapeutic gas delivery via microbubbles and liposomes

Samantha M. Fix et al.

JOURNAL OF CONTROLLED RELEASE (2015)

添加到收藏夹
Article Physics, Fluids & Plasmas

Ultrasound-induced inertial cavitation from gas-stabilizing nanoparticles

J. J. Kwan et al.

PHYSICAL REVIEW E (2015)

添加到收藏夹
Article Acoustics

Real-time detection of intracellular reactive oxygen species and mitochondrial membrane potential in THP-1 macrophages during ultrasonic irradiation for optimal sonodynamic therapy

Xin Sun et al.

ULTRASONICS SONOCHEMISTRY (2015)

添加到收藏夹
Article Acoustics

LOW-INTENSITY ULTRASOUND PROMOTES CLATHRIN-DEPENDENT ENDOCYTOSIS FOR DRUG PENETRATION INTO TUMOR CELLS

Sophie Tardoski et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2015)

添加到收藏夹
Article Acoustics

IN VITRO INVESTIGATION OF THE INDIVIDUAL CONTRIBUTIONS OF ULTRASOUND-INDUCED STABLE AND INERTIAL CAVITATION IN TARGETED DRUG DELIVERY

Dana Gourevich et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2015)

添加到收藏夹
Article Biochemistry & Molecular Biology

Recruitment of endocytosis in sonopermeabilization-mediated drug delivery: a real-time study

Marc Derieppe et al.

PHYSICAL BIOLOGY (2015)

添加到收藏夹
Review Pharmacology & Pharmacy

Acoustic behavior of microbubbles and implications for drug delivery

Klazina Kooiman et al.

ADVANCED DRUG DELIVERY REVIEWS (2014)

添加到收藏夹
Review Pharmacology & Pharmacy

Nucleic acid delivery with microbubbles and ultrasound

Joshua J. Rychak et al.

ADVANCED DRUG DELIVERY REVIEWS (2014)

添加到收藏夹
Article Engineering, Biomedical

Tumor-penetrating codelivery of siRNA and paclitaxel with ultrasound-responsive nanobubbles hetero-assembled from polymeric micelles and liposomes

Tinghui Yin et al.

BIOMATERIALS (2014)

添加到收藏夹
Review Chemistry, Multidisciplinary

Cell experimental studies on sonoporation: State of the art and remaining problems

Hao Yu et al.

JOURNAL OF CONTROLLED RELEASE (2014)

添加到收藏夹
Article Chemistry, Multidisciplinary

Hollow Mesoporous Organosilica Nanoparticles: A Generic Intelligent Framework-Hybridization Approach for Biomedicine

Yu Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

添加到收藏夹
Article Nanoscience & Nanotechnology

Biogenic gas nanostructures as ultrasonic molecular reporters

Mikhail G. Shapiro et al.

NATURE NANOTECHNOLOGY (2014)

添加到收藏夹
Article Chemistry, Multidisciplinary

Ultrasonic gene and drug delivery using eLiposomes

Marjan Javadi et al.

JOURNAL OF CONTROLLED RELEASE (2013)

添加到收藏夹
Article Chemistry, Multidisciplinary

Evidence for a new mechanism behind HIFU-triggered release from liposomes

Chris Oerlemans et al.

JOURNAL OF CONTROLLED RELEASE (2013)

添加到收藏夹
Article Multidisciplinary Sciences

Mesenchymal Stem Cell Transplantation Enhancement in Myocardial Infarction Rat Model under Ultrasound Combined with Nitric Oxide Microbubbles

Jiayi Tong et al.

PLOS ONE (2013)

添加到收藏夹
Article Acoustics

MEMBRANE PERFORATION AND RECOVERY DYNAMICS IN MICROBUBBLE-MEDIATED SONOPORATION

Yaxin Hu et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2013)

添加到收藏夹
Article Chemistry, Multidisciplinary

Controlled permeation of cell membrane by single bubble acoustic cavitation

Y. Zhou et al.

JOURNAL OF CONTROLLED RELEASE (2012)

添加到收藏夹
Article Acoustics

ULTRASOUND-INDUCED CALCEIN RELEASE FROM eLIPOSOMES

James R. Lattin et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2012)

添加到收藏夹
Article Medicine, Research & Experimental

Theranostic Oxygen Delivery Using Ultrasound and Microbubbles

James J. Kwan et al.

THERANOSTICS (2012)

添加到收藏夹
Review Oncology

Immunogenic cell death and DAMPs in cancer therapy

Dmitri V. Krysko et al.

NATURE REVIEWS CANCER (2012)

添加到收藏夹
Article Pharmacology & Pharmacy

Doxorubicin and paclitaxel loaded microbubbles for ultrasound triggered drug delivery

Michael C. Cochran et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)

添加到收藏夹
Article Biophysics

Effects of shear stress cultivation on cell membrane disruption and intracellular calcium concentration in sonoporation of endothelial cells

Juyoung Park et al.

JOURNAL OF BIOMECHANICS (2011)

添加到收藏夹
Article Chemistry, Multidisciplinary

Sonoporation of endothelial cells by vibrating targeted microbubbles

Klazina Kooiman et al.

JOURNAL OF CONTROLLED RELEASE (2011)

添加到收藏夹
Article Pharmacology & Pharmacy

Distearoylphosphatidylethanolamine-based liposomes for ultrasound-mediated drug delivery

Tove J. Evjen et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2010)

添加到收藏夹
Article Radiology, Nuclear Medicine & Medical Imaging

Optimal Enhancement Configuration of Silica Nanoparticles for Ultrasound Imaging and Automatic Detection at Conventional Diagnostic Frequencies

Sergio Casciaro et al.

INVESTIGATIVE RADIOLOGY (2010)

添加到收藏夹
Article Chemistry, Multidisciplinary

New doxorubicin-loaded phospholipid microbubbles for targeted tumor therapy: In-vivo characterization

Steliyan Tinkov et al.

JOURNAL OF CONTROLLED RELEASE (2010)

添加到收藏夹
Article Acoustics

SAVING CELLS FROM ULTRASOUND-INDUCED APOPTOSIS: QUANTIFICATION OF CELL DEATH AND UPTAKE FOLLOWING SONICATION AND EFFECTS OF TARGETED CALCIUM CHELATION

J. D. Hutcheson et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2010)

添加到收藏夹
Article Engineering, Biomedical

Perfluorocarbon Nanoemulsions for Quantitative Molecular Imaging and Targeted Therapeutics

Megan M. Kaneda et al.

ANNALS OF BIOMEDICAL ENGINEERING (2009)

添加到收藏夹
Article Biophysics

Sonoporation by Single-Shot Pulsed Ultrasound with Microbubbles Adjacent to Cells

Nobuki Kudo et al.

BIOPHYSICAL JOURNAL (2009)

添加到收藏夹
Article Cardiac & Cardiovascular Systems

Ultrasound and Microbubble-Targeted Delivery of Macromolecules Is Regulated by Induction of Endocytosis and Pore Formation

Bernadet D. M. Meijering et al.

CIRCULATION RESEARCH (2009)

添加到收藏夹
Review Chemistry, Medicinal

Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment

Ghaleb A. Husseini et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2009)

添加到收藏夹
Article Acoustics

SONOPORATION BY ULTRASOUND-ACTIVATED MICROBUBBLE CONTRAST AGENTS: EFFECT OF ACOUSTIC EXPOSURE PARAMETERS ON CELL MEMBRANE PERMEABILITY AND CELL VIABILITY

Raffi Karshafian et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2009)

添加到收藏夹
Review Pharmacology & Pharmacy

Microbubbles in ultrasound-triggered drug and gene delivery

Sophie Hernot et al.

ADVANCED DRUG DELIVERY REVIEWS (2008)

添加到收藏夹
Article Acoustics

Nitric oxide delivery by ultrasonic cracking: Some limitations

Michiel Postema et al.

ULTRASONICS (2006)

添加到收藏夹
Review Hematology

Ultrasound thrombolysis

S Pfaffenberger et al.

THROMBOSIS AND HAEMOSTASIS (2005)

添加到收藏夹
Article Acoustics

Ultrasound-induced cell membrane porosity

CX Deng et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2004)

添加到收藏夹
Article Chemistry, Multidisciplinary

Drug delivery in polymeric micelles: from in vitro to in vivo

N Rapoport et al.

JOURNAL OF CONTROLLED RELEASE (2003)

添加到收藏夹
Article Pharmacology & Pharmacy

Sequestration and ultrasound-induced release of doxorubicin from stabilized pluronic P105 micelles

JD Pruitt et al.

DRUG DELIVERY (2002)

添加到收藏夹
研讨会 海报 问题 讨论圈 基金 期刊 论文 科研社交 资讯集成 审稿人 关于我们 常见问题 移动App 隐私条款 使用条款
© Peeref 2019-2024. All rights reserved.