Stability-Indicating HPTLC Method for Determination of Remogliflozin Etabonate and Vildagliptin in Tablets

Article Education, Scientific Disciplines

Smart Spectrophotometric Method Development for Simultaneous Estimation of Antidiabetic Drugs in Formulations

Mahesh Attimarad et al.

Summary: Two simple rapid derivative spectrophotometric methods were developed for the analysis of vildagliptin and remogliflozin. Both methods showed good linearity and sensitivity, and the assay results of the formulation were in agreement with the labeled concentration.

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (2022)

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Article Education, Scientific Disciplines

Rapid Simultaneous Quantitative Analysis of Hypoglycemic agents by RP HPLC: Development, Validation and Application to Medicine

Mahesh Attimarad et al.

Summary: A simple and rapid RP-HPLC method was developed and validated for the quality control of a new formulation containing vildagliptin and remogliflozin. The method showed satisfactory linearity and accuracy, and was proven to be robust. It can be effectively used for the simultaneous quantification of vildagliptin and remogliflozin in the formulation.

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (2022)

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Article Biochemistry & Molecular Biology

An Experimental Design Approach to Quantitative Expression for Quality Control of a Multicomponent Antidiabetic Formulation by the HILIC Method

Mahesh Attimarad et al.

Summary: A rapid and reproducible hydrophilic liquid chromatography (HILIC) method was developed for the simultaneous determination of remogliflozin etabonate (RE), vildagliptin (VD), and metformin (MF). The method was optimized using a central composite experimental design and validated according to ICH guidelines. The method showed excellent linearity and accuracy, and can be used for the quality assurance of pharmaceutical preparations.

MOLECULES (2022)

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Article Pharmacology & Pharmacy

Simple and Sensitive RP-HPLC and UV Spectroscopic Methods for the Determination of Remogliflozin Etabonate in Pure and Pharmaceutical Formulations

Nandeesha Itigimatha et al.

Summary: Simple, accurate, reproducible, and precise reverse phase-high performance liquid chromatography (RP-HPLC) and ultraviolet (UV) spectroscopic methods have been developed for the determination of remogliflozin etabonate (RMZ) in bulk and dosage forms.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES (2022)

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Article

HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY (HPTLC) METHOD DEVELOPMENT AND VALIDATION FOR DETERMINATION OF REMOGLIFLOZIN ETABONATE AND VILDAGLIPTIN IN BULK AND ITS TABLET FORMULATION

SARANG V. BADKE et al.

International Journal of Applied Pharmaceutics (2022)

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Article Spectroscopy

Environmental sustainable mathematically processed UV spectroscopic methods for quality control analysis of remogliflozin and teneligliptin: Evaluation of greenness and whiteness

Mahesh Attimarad et al.

Summary: Environmental sustainable analytical methods were developed for quality control study of multicomponent formulations consisting of remogliflozin and teneligliptin based on mathematical modification of UV absorption spectra. These methods exhibited good sensitivity and selectivity, allowing simultaneous quantification of the two components.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

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Article Pharmacology & Pharmacy

A Novel Analytical Method for the Simultaneous Estimation of Remogliflozin and Metformin Hydrochloride by UPLC/PDA in Bulk and Formulation Application to the Estimation of Product Traces

Mohan Rao Tammisetty et al.

Summary: A validated method has been developed for the evaluation of remogliflozin and metformin hydrochloride in bulk and in the formulation, as well as for cleaning samples. The results obtained with this method were accurate and precise.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

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Article Environmental Sciences

Development and Validation of Green UV Derivative Spectrophotometric Methods for Simultaneous Determination Metformin and Remogliflozin from Formulation: Evaluation of Greenness

Mahesh Attimarad et al.

Summary: The recent trend in green analytical chemistry focuses on the development of environmentally friendly methods using green solvents, with three ecofriendly manipulated UV spectroscopic techniques validated for the quantification of REM and MET tablets. The methods showed good linearity, sensitivity, accuracy, and precision, and were found to be suitable for regular quality control of REM and MET formulation in laboratory prepared mixtures and tablets. The proposed approaches were simple, accurate, sensitive, economic, environmentally friendly, and evaluated as eco-friendly.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Article Biochemistry & Molecular Biology

Development of Ecofriendly Derivative Spectrophotometric Methods for the Simultaneous Quantitative Analysis of Remogliflozin and Vildagliptin from Formulation

Mahesh Attimarad et al.

Summary: Three rapid, accurate, and ecofriendly spectrophotometric methods using water as dilution solvent were validated for the concurrent quantification of RGE and VGN. The methods demonstrated good linearity, recovery, and accuracy, suitable for routine quality control studies of pharmaceutical preparations. The ecofriendly nature of the procedures was confirmed through evaluation using GAPI method.

MOLECULES (2021)

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Article Chemistry, Analytical