4.5 Article

Synergistic cytotoxicity of perifosine and ABT-737 to colon cancer cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells

Emily M. E. Barnes et al.

BRITISH JOURNAL OF CANCER (2020)

Review Cell Biology

BCL-2 family isoforms in apoptosis and cancer

Chloe F. A. Warren et al.

CELL DEATH & DISEASE (2019)

Review Biotechnology & Applied Microbiology

3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs

Ana S. Nunes et al.

BIOTECHNOLOGY AND BIOENGINEERING (2019)

Article Medicine, General & Internal

2D and 3D cell cultures - a comparison of different types of cancer cell cultures

Marta Kapalczynska et al.

ARCHIVES OF MEDICAL SCIENCE (2018)

Article Critical Care Medicine

Drug-Penetration Gradients Associated with Acquired Drug Resistance in Patients with Tuberculosis

Keertan Dheda et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)

Article Pharmacology & Pharmacy

Comparative Assay of 2D and 3D Cell Culture Models: Proliferation, Gene Expression and Anticancer Drug Response

Aline G. Souza et al.

CURRENT PHARMACEUTICAL DESIGN (2018)

Review Biochemistry & Molecular Biology

Heterogeneity in Colorectal Cancer: A Challenge for Personalized Medicine?

Chiara Molinari et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Oncology

Combine and conquer: challenges for targeted therapy combinations in early phase trials

Juanita S. Lopez et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2017)

Article Cell Biology

Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate

Jarmila Navratilova et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2017)

Review Biochemistry & Molecular Biology

Targeting the Akt/PI3K Signaling Pathway as a Potential Therapeutic Strategy for the Treatment of Pancreatic Cancer

Safieh Ebrahimi et al.

CURRENT MEDICINAL CHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Perifosine and ABT-737 synergistically inhibit lung cancer cells in vitro and in vivo

Jie Shen et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Review Oncology

Role of Akt signaling in resistance to DNA-targeted therapy

Abolfazl Avan et al.

WORLD JOURNAL OF CLINICAL ONCOLOGY (2016)

Review Biochemistry & Molecular Biology

Portrait of the PI3K/AKT pathway in colorectal cancer

Stine Aske Danielsen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2015)

Article Multidisciplinary Sciences

Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance

Stefany Moreno-Gamez et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemical Research Methods

Spatial Heterogeneity in Drug Concentrations Can Facilitate the Emergence of Resistance to Cancer Therapy

Feng Fu et al.

PLOS COMPUTATIONAL BIOLOGY (2015)

Review Biochemical Research Methods

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

Rasheena Edmondson et al.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2014)

Article Oncology

Activation of the PI3K/AKT pathway correlates with prognosis in stage II colon cancer

K. Malinowsky et al.

BRITISH JOURNAL OF CANCER (2014)

Article Biochemistry & Molecular Biology

Synergistic Enhancement of Cancer Therapy Using a Combination of Ceramide and Docetaxel

Li-Xia Feng et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Review Biochemistry & Molecular Biology

Perifosine, an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity

Paul G. Richardson et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2012)

Review Biochemistry & Molecular Biology

BH3-only proteins: Orchestrators of apoptosis

Aisha Shamas-Din et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)

Article Oncology

The BH3 Mimetic ABT-737 Induces Cancer Cell Senescence

Jin H. Song et al.

CANCER RESEARCH (2011)

Article Medicine, Research & Experimental

Hypoxic human cancer cells are sensitized to BH-3 mimetic-induced apoptosis via downregulation of the Bcl-2 protein Mcl-1

Luke R. E. Harrison et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Review Medicine, Research & Experimental

Drug Resistance and Cellular Adaptation to Tumor Acidic pH Microenvironment

Jonathan W. Wojtkowiak et al.

MOLECULAR PHARMACEUTICS (2011)

Article Oncology

ABT-737, a BH3 mimetic, induces glutathione depletion and oxidative stress

Adrienne N. Howard et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)

Article Oncology

Perifosine: Update on a Novel Akt Inhibitor

Joell J. Gills et al.

CURRENT ONCOLOGY REPORTS (2009)

Article Genetics & Heredity

The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers

Julia Ling-Yu Chen et al.

PLOS GENETICS (2008)

Review Oncology

Treatment resistance of solid tumors - Role of hypoxia and anemia

P Vaupel et al.

MEDICAL ONCOLOGY (2001)

Article Biochemistry & Molecular Biology

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

EP Rogakou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)