4.5 Editorial Material

JCF Heart Failure Year-In-Review 2022 ... The Best is Yet to Come! ...

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Article Cardiac & Cardiovascular Systems

Lead With the Why: Research Recruitment of Older Adults With HF During COVID-19

Lyndsay Degroot

Summary: Recruiting older adults with advanced heart failure is challenging, especially for doctoral students with limited resources. Successful recruitment requires considering the context and being sensitive to the clinical partners providing care.

JOURNAL OF CARDIAC FAILURE (2022)

Review Cardiac & Cardiovascular Systems

Emerging Implantable-Device Technology for Patients at the Intersection of Electrophysiology and Heart Failure Interdisciplinary Care

Ioannis Mastoris et al.

Summary: Cardiac implantable electronic devices, including implantable cardioverter-defibrillators and therapy, are part of guideline-indicated treatment for heart failure patients. Technological advancements have allowed the detection of physiological parameters for clinical prediction. Emerging technologies may benefit patients without indications for cardiac resynchronization. Standardized workflow and interdisciplinary management are necessary for high-quality care.

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

Multiple Cardiac Biomarker Testing Among Patients With Acute Dyspnea From the ICON-RELOADED Study

Andrew Abboud et al.

Summary: Among patients with acute dyspnea, measuring concentrations of NT-proBNP, high-sensitivity cardiac troponin T, and insulin-like growth factor binding protein-7 can predict and evaluate the condition, and play an important role in assessing the risk of short-term mortality and heart failure rehospitalization.

JOURNAL OF CARDIAC FAILURE (2022)

Review Cardiac & Cardiovascular Systems

The Ecosystem to Support People With Heart Failure

Robert M. Califf

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

Arterial Stiffness and Vascular Load in HFpEF: Differences Among Women and Men

Emily S. Lau et al.

Summary: This study found that arterial stiffness is higher in women with HFpEF than in men, and it is associated with abnormally steep increases in pulmonary capillary wedge pressure with exercise, particularly in women. Arterial stiffness may preferentially contribute to abnormal diastolic function during exercise in women with HFpEF compared with men.

JOURNAL OF CARDIAC FAILURE (2022)

Review Cardiac & Cardiovascular Systems

Sex Differences in Heart Failure

Anuradha Lala et al.

Summary: Heart failure shows gender differences in prevalence, risk factors, pathophysiology, presentation, and therapies. More research is needed to fully understand and explore these differences.

JOURNAL OF CARDIAC FAILURE (2022)

Editorial Material Cardiac & Cardiovascular Systems

Cardiac Xenotransplantation: Rebirth Amidst an Uncertain Future

Mandeep R. Mehra

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

Coronavirus Disease-2019 and Heart Failure: A Scientific Statement From the Heart Failure Society of America

Ankeet S. Bhatt et al.

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

2022 American College of Cardiology/American Heart Association/Heart Failure Society of America Guideline for the Management of Heart Failure: Executive Summary

Paul A. Heidenreich et al.

Summary: The 2022 heart failure guideline aims to provide recommendations for the prevention, diagnosis, and treatment of patients with heart failure. Based on contemporary evidence, the guideline seeks to improve quality of care and align with patients' interests.

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure

Paul A. Heidenreich et al.

Summary: The 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure provides patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure. It is based on contemporary evidence and aims to improve quality of care and align with patients' interests.

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

The Great Asian Mismatch: Training Versus Care in Heart Failure

Raja Ezman Raja Shariff et al.

Summary: The prevalence of heart failure is higher in South-East Asia compared to Western countries, but there is a lack of established fellowship programs in the region. Developing tailored curricula and promoting collaboration between local and international societies can help bridge the gap and provide equitable training.

JOURNAL OF CARDIAC FAILURE (2022)

Editorial Material Cardiac & Cardiovascular Systems

A Clinician's Guide to the 2022 ACC/AHA/HFSA Guideline for the Management of Heart Failure

Michelle M. Kittleson

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

Medical Therapy During Hospitalization for Heart Failure With Reduced Ejection Fraction: The VICTORIA Registry

Stephen J. Greene et al.

Summary: This study investigated the medication changes during hospitalizations for heart failure with reduced ejection fraction (HFrEF) in North American clinical practice. The majority of eligible patients remained on stable subtarget doses or without medication at admission and discharge, with favorable medication changes associated with hospitalization in Canada and specific patient characteristics.

JOURNAL OF CARDIAC FAILURE (2022)

Editorial Material Cardiac & Cardiovascular Systems

Women Empowering Women in Heart Transplantation and Mechanical Circulatory Support

Anju Bhardwaj et al.

JOURNAL OF CARDIAC FAILURE (2022)

Editorial Material Cardiac & Cardiovascular Systems

Michele-This Is My Why, Now Let's Find the Way ...

Vanessa Blumer

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

Increased Opportunities for Transplantation for Women in the New Heart Allocation System

Ersilia M. Defilippis et al.

Summary: In the 2018 heart transplantation allocation system, there are still disparities between women and men in waitlist and post-transplant survival rates, but there has been an improvement in transplant opportunities for women. The new allocation system provides more transplant opportunities for women.

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

Center Variability in Patient Outcomes Following HeartMate 3 Implantation: An Analysis of the MOMENTUM 3 Trial

Manreet K. Kanwar et al.

Summary: The study found significant variability in mortality and adverse event rates across LVAD treatment centers. Factors such as age, gender, treatment intent, and patient condition may contribute to the differences in outcomes among different centers. Further research is needed to improve our understanding of the drivers of outcome variability and identify best practices for achieving high-performance outcomes in LVAD support.

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

Multiple cArdiac seNsors for mAnaGEment of Heart Failure (MANAGE-HF) - Phase I Evaluation of the Integration and Safety of the HeartLogic Multisensor Algorithm in Patients With Heart Failure

Adrian F. Hernandez et al.

Summary: The clinical integration and safety of the HeartLogic multisensor index and alerts in heart failure (HF) care were evaluated. The study found that alert cases prompted augmentation of HF medications and were associated with faster recovery of the HeartLogic Index. Although there were a few serious adverse events related to alert-prompted medication change, the overall implementation of HeartLogic alert management was deemed safe in HF care. The levels of NTproBNP significantly decreased during the treatment process.

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

The Impact of Health Care Disparities on Patients With Heart Failure

Alanna Morris et al.

Summary: Heart failure is associated with high morbidity, mortality, and costs, and the availability of treatments is expanding rapidly. However, there are also growing concerns about disparities in incident HF risk and treatment delivery, which affect different racial, ethnic, and socioeconomic groups. Social determinants of health further complicate HF risk and treatment, making it important for clinicians and researchers to assess both biological and social factors in vulnerable populations. This document highlights healthcare disparities in HF care and provides a framework for reducing access and outcome inequalities over time.

JOURNAL OF CARDIAC FAILURE (2022)

Article Cardiac & Cardiovascular Systems

Electronic Alerts to Improve Heart Failure Therapy in Outpatient Practice A Cluster Randomized Trial

Lama Ghazi et al.

Summary: Using targeted and tailored electronic health record (EHR) alerts to recommend guideline-directed medical therapy (GDMT) in eligible patients with heart failure with reduced ejection fraction (HFrEF) can significantly increase GDMT use within 30 days.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

Article Medicine, General & Internal

Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial

Justin A. Ezekowitz et al.

Summary: Restricting dietary sodium intake does not reduce the occurrence of clinical events in patients with heart failure.

LANCET (2022)

Article Medicine, General & Internal

Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN) : an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial

Paul R. Kalra et al.

Summary: This study evaluated the long-term effects of intravenous ferric derisomaltose on cardiovascular events in patients with heart failure. The results showed that treatment with ferric derisomaltose was associated with a lower risk of hospital admissions for heart failure and cardiovascular death, further supporting the benefit of iron repletion in this patient population.

LANCET (2022)

Article Medicine, General & Internal

Safety, tolerability, and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial

Alexandre Mebazaa et al.

Summary: This study aimed to investigate the impact of guideline-directed medical therapy dose and up-titration pace on the efficacy and safety of patients admitted to the hospital for acute heart failure. The results showed that compared with usual care, high-intensity care significantly reduced the risk of heart failure readmission or all-cause death within 180 days.

LANCET (2022)

Article Cardiac & Cardiovascular Systems

A Randomized Controlled Trial of Mobile Health Intervention in Patients With Heart Failure and Diabetes

G. Michael Felker et al.

Summary: In patients with both heart failure and diabetes, a 3-month mHealth intervention significantly improved daily physical activity, health-related quality of life, and markers of cardiovascular health, but had no effect on medication adherence.

JOURNAL OF CARDIAC FAILURE (2022)

Editorial Material Cardiac & Cardiovascular Systems

Words to Leave By: Bridges Out of the Quiet Place

Kristin Flanary

JOURNAL OF CARDIAC FAILURE (2022)

Article Medicine, General & Internal

Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction

S. D. Solomon et al.

Summary: The study shows that SGLT2 inhibitors are effective in reducing the risk of hospitalization for heart failure and cardiovascular death among patients with chronic heart failure and a left ventricular ejection fraction of 40% or less. However, whether they are effective in patients with a higher left ventricular ejection fraction remains uncertain.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

Article Medicine, General & Internal

Acetazolamide in Acute Decompensated Heart Failure with Volume Overload

Wilfried Mullens et al.

Summary: The addition of acetazolamide to loop diuretic therapy in patients with acute decompensated heart failure results in a higher incidence of successful decongestion without increasing adverse events.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

Editorial Material Cardiac & Cardiovascular Systems

#BeaconsOfLight

Mark H. Drazner

JOURNAL OF CARDIAC FAILURE (2021)