Homogeneous Pt nanostructures surface functionalized with phenylboronic acid phosphonic acid derivatives as potential biochemical nanosensors and drugs: SERS and TERS studies

Here, surface-enhanced Raman scattering (SERS) and tip-enhanced Raman scattering (TERS) were used to characterize the selective adsorption of N-substituted 4-[(NH-R)(phosphono)-S-methyl]phenylboronic acids on the surface of platinum nanoparticles (PtNPs) from an aqueous solution and from air. The nature of the interaction of the studied compounds with the PtNPs/H2O and PtNPs/air interfaces was discussed and compared. For this purpose, 4-[(N-anilino)(phosphono)-S-methyl]phenylboronic acid (1-PBA-PA) and its two analogs (2-PBA-PA and bis{1-PBA-PA}) as well as the PtNPs were synthesized in surfactant/ion-free solution via a synthetic route that allows control of the size and morphology of the NPs. The positively charged PtNPs with a size of similar to 12 nm were characterized by ultraviolet-visible spectroscopy (UV-Vis), dynamic light scattering (DLS), scanning electron microscopy (SEM), and X-ray powder diffraction (XRD).

Automated summary

In this study, surface-enhanced Raman scattering (SERS) and tip-enhanced Raman scattering (TERS) were used to investigate the selective adsorption of N-substituted 4-[(NH-R)(phosphono)-S-methyl]phenylboronic acids on platinum nanoparticles (PtNPs) surfaces from aqueous and air environments. The interaction between the studied compounds and PtNPs/H2O and PtNPs/air interfaces was analyzed and compared. PtNPs with a size of approximately 12 nm were synthesized via a surfactant/ion-free method, and their characteristics were determined using UV-Vis spectroscopy, dynamic light scattering (DLS), scanning electron microscopy (SEM), and X-ray powder diffraction (XRD).