A 20-year patent review and innovation trends on hydrogel-based coatings used for medical device biofabrication

This patent review encapsulates information that could be used as a reference by researchers in the fields of coatings and interfaces, biofabrication, tissue engineering, biomaterials, and biomedical engineering, as well as those especially interested in the formulation of hydrogel coatings. The state has been reviewed by introducing what has been innovated, invented, and patented in relation to hydrogel coatings. A detailed analysis of the patentability of hydrogel applications, such as the coating of medical devices to enhance their clinical performance, has been provided. During a search, 2937 patent documents were found. 2012 was the year with the most patent documents (177). Based on the patent classification, all patent documents and most inventions are intended for biomaterials for coating prostheses characterized by their function or physical properties, such as macromolecular materials, hydrogels, and biologically active materials. Additionally, research based on medicinal formulations with unique physical forms is concentrated in the majority of patents, according to knowledge clusters and expert driving factors. Finally, to demonstrate the innovation trends in hydrogel-based coatings, a selection of relevant patent applications and granted patents is proposed at the end of this paper, along with some examples of commercial products based on the patented technologies.

Automated summary

This patent review provides a comprehensive overview of innovations, inventions, and patents related to hydrogel coatings, which can be a valuable reference for researchers in the fields of coatings and interfaces, biofabrication, tissue engineering, biomaterials, and biomedical engineering. It specifically focuses on the patentability of hydrogel applications, such as coating medical devices to improve their clinical performance. A total of 2937 patent documents were found, with the year 2012 having the highest number of patent documents (177). The majority of patents and inventions are related to biomaterials for coating prostheses, characterized by their function or physical properties, such as macromolecular materials, hydrogels, and biologically active materials. The paper also highlights the research on medicinal formulations with unique physical forms, based on clusters of knowledge and expert driving factors. Finally, a selection of relevant patent applications, granted patents, and commercial products based on patented technologies are presented to illustrate the innovation trends in hydrogel-based coatings.