相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Targeting insulin-like growth factor-1 receptor (IGF1R) for brain delivery of biologics
Wael Alata et al.
FASEB JOURNAL (2022)
Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies
Laura R. Grauslund et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2021)
Defining the epitope of a blood-brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor
Joey Sheff et al.
SCIENTIFIC REPORTS (2021)
Controlled Signaling-Insulin-Like Growth Factor Receptor Endocytosis and Presence at Intracellular Compartments
Leonie Rieger et al.
FRONTIERS IN ENDOCRINOLOGY (2021)
Teprotumumab for patients with active thyroid eye disease: a pooled data analysis, subgroup analyses, and off-treatment follow-up results from two randomised, double-masked, placebo-controlled, multicentre trials
George J. Kahaly et al.
LANCET DIABETES & ENDOCRINOLOGY (2021)
pH-responsive antibodies for therapeutic applications
Tomasz Klaus et al.
JOURNAL OF BIOMEDICAL SCIENCE (2021)
Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain
Theresia Gutmann et al.
JOURNAL OF CELL BIOLOGY (2020)
Efficacy of the Antibody-Drug Conjugate W0101 in Preclinical Models of IGF-1 Receptor Overexpressing Solid Tumors
Barbara Akla et al.
MOLECULAR CANCER THERAPEUTICS (2020)
Impact of Glycosylation on the Comparability of the Higher-Order Structures in Idursulfase by Hydrogen-Deuterium Exchange Mass Spectrometry
Chris Barton et al.
ANALYTICAL CHEMISTRY (2020)
IGF-1R drugs travel from cancer cradle to Graves'
Elie Dolgin
NATURE BIOTECHNOLOGY (2020)
Hydrogen deuterium exchange mass spectrometry with improved electrochemical reduction enables comprehensive epitope mapping of a therapeutic antibody to the cysteine-knot containing vascular endothelial growth factor
Gerard Comamala et al.
ANALYTICA CHIMICA ACTA (2020)
Integrated Approach for Characterizing Bispecific Antibody/Antigens Complexes and Mapping Binding Epitopes with SEC/MALS, Native Mass Spectrometry, and Protein Footprinting
Richard Y-C Huang et al.
ANALYTICAL CHEMISTRY (2020)
Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human
Wandong Zhang et al.
FLUIDS AND BARRIERS OF THE CNS (2020)
Structural basis of the activation of type 1 insulin-like growth factor receptor
Jie Li et al.
NATURE COMMUNICATIONS (2019)
High-Resolution HDX-MS of Cytochrome c Using Pepsin/Fungal Protease Type XIII Mixed Bed Column
Yoshitomo Hamuro et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2019)
Hydrogen/deuterium exchange mass spectrometry and computational modeling reveal a discontinuous epitope of an antibody/TL1A Interaction
Richard Y. -C. Huang et al.
MABS (2018)
Neurocognitive and somatic stabilization in pediatric patients with severe Mucopolysaccharidosis Type I after 52 weeks of intravenous brain-penetrating insulin receptor antibody-iduronidase fusion protein (valanafusp alpha): an open label phase 1-2 trial
Roberto Giugliani et al.
ORPHANET JOURNAL OF RARE DISEASES (2018)
A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis
Maria Ribecco-Lutkiewicz et al.
SCIENTIFIC REPORTS (2018)
Emerging Technologies for Delivery of Biotherapeutics and Gene Therapy Across the Blood-Brain Barrier
Danica B. Stanimirovic et al.
BIODRUGS (2018)
Application of Dual Protease Column for HDX-MS Analysis of Monoclonal Antibodies
Sasidhar N. Nirudodhi et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Assisted Design of Antibody and Protein Therapeutics (ADAPT)
Victor Vivcharuk et al.
PLOS ONE (2017)
Update of IGF-1 receptor inhibitor (ganitumab, dalotuzumab, cixutumumab, teprotumumab and figitumumab) effects on cancer therapy
Xiao Qu et al.
ONCOTARGET (2017)
Disulfide Linkage Characterization of Disulfide Bond-Containing Proteins and Peptides by Reducing Electrochemistry and Mass Spectrometry
Christian N. Cramer et al.
ANALYTICAL CHEMISTRY (2016)
Higher-order structural interrogation of antibodies using middle-down hydrogen/deuterium exchange mass spectrometry
Jingxi Pan et al.
CHEMICAL SCIENCE (2016)
Conformational Analysis of Large and Highly Disulfide-Stabilized Proteins by Integrating Online Electrochemical Reduction into an Optimized H/D Exchange Mass Spectrometry Workflow
Esben Trabjerg et al.
ANALYTICAL CHEMISTRY (2015)
A phase 3 randomized, double-blind, placebo-controlled trial of ganitumab or placebo in combination with gemcitabine as first-line therapy for metastatic adenocarcinoma of the pancreas: the GAMMA trial
C. S. Fuchs et al.
ANNALS OF ONCOLOGY (2015)
Role of IGF1R in breast cancer subtypes, sternness, and lineage differentiation
Susan M. Farabaugh et al.
FRONTIERS IN ENDOCRINOLOGY (2015)
Targeting the IGF-1R: the tale of the tortoise and the hare
Caitrin Crudden et al.
FRONTIERS IN ENDOCRINOLOGY (2015)
Electrochemical Reduction of Disulfide-Containing Proteins for Hydrogen/Deuterium Exchange Monitored by Mass Spectrometry
Simon Mysling et al.
ANALYTICAL CHEMISTRY (2014)
Identification of a Small Molecular Insulin Receptor Agonist With Potent Antidiabetes Activity
Guifen Qiang et al.
DIABETES (2014)
A Human Blood-Brain Barrier Transcytosis Assay Reveals Antibody Transcytosis Influenced by pH-Dependent Receptor Binding
Hadassah Sade et al.
PLOS ONE (2014)
Mass Spec Studio for Integrative Structural Biology
Martial Rey et al.
STRUCTURE (2014)
Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function
Alaide Morcavallo et al.
FRONTIERS IN ENDOCRINOLOGY (2014)
Epitope-Specific Mechanisms of IGF1R Inhibition by Ganitumab
Frank J. Calzone et al.
PLOS ONE (2013)
IGF-1R as an anti-cancer target-trials and tribulations
Helen X. Chen et al.
CHINESE JOURNAL OF CANCER (2013)
Mapping of discontinuous conformational epitopes by amide hydrogen/deuterium exchange mass spectrometry and computational docking
Deepangi Pandit et al.
JOURNAL OF MOLECULAR RECOGNITION (2012)
Minimizing Back Exchange in the Hydrogen Exchange-Mass Spectrometry Experiment
Benjamin T. Walters et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target
Y. Joy Yu et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Fine Details of IGF-1R Activation, Inhibition, and Asymmetry Determined by Associated Hydrogen/Deuterium-Exchange and Peptide Mass Mapping
Damian Houde et al.
STRUCTURE (2011)
Characterization of Inhibitory Anti-insulin-like Growth Factor Receptor Antibodies with Different Epitope Specificity and Ligand-blocking Properties IMPLICATIONS FOR MECHANISM OF ACTION IN VIVO
Adam Doern et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Computational characterization of B-cell epitopes
Nimrod D. Rubinstein et al.
MOLECULAR IMMUNOLOGY (2008)
Alanine scanning mutagenesis of a type 1 insulin-like growth factor receptor ligand binding site
J Whittaker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Interactions of IGF-1 with the blood-brain barrier in vivo and in situ
WH Pan et al.
NEUROENDOCRINOLOGY (2000)
分享论文
