4.6 Article

Amino acids grafted-chitosan/glycerophosphate hydrogel for controlled release of berberine hydrochloride

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Polymer Science

Chitosan hydrogels chemically crosslinked with L-glutamic acid and their potential use in drug delivery

D. E. Rodriguez-Felix et al.

Summary: Controlled drug release systems using hydrogels have the advantages of minimizing side effects and maintaining a stable therapeutic concentration. This study suggests the synthesis of chitosan hydrogels crosslinked with glutamic acid for controlled drug release. The hydrogels exhibited excellent swelling capacity and antimicrobial activity according to various characterizations.

POLYMER BULLETIN (2023)

Article Polymer Science

Dodecenylsuccinic anhydride modified chitosan hydrogels for the sustained delivery of hydrophobic drugs. The case of thymol buccal delivery

Maria I. Alvarez Echazu et al.

Summary: Chitosan hydrogels modified by DDSA exhibit improved mechanical properties and cytotoxicity. Incorporation of thymol shows antimicrobial and antioxidant activities. The study suggests that DDSA-chitosan hydrogels could be promising for the sustained local delivery of hydrophobic drugs.

JOURNAL OF APPLIED POLYMER SCIENCE (2022)

Article Pharmacology & Pharmacy

Preparation and performance of chitosan/cyclodextrin-g-glutamic acid thermosensitive hydrogel

Hui Yun Zhou et al.

Summary: In this study, a chitosan/cyclodextrin derivative thermosensitive hydrogel was prepared and showed temperature sensitivity, stable structure, sustained release effect, and antibacterial activity when loaded with berberine hydrochloride.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)

Article Marine & Freshwater Biology

Design and evaluation of chitosan-amino acid thermosensitive hydrogel

Jianan Tong et al.

Summary: Chitosan-amino acid thermosensitive hydrogels demonstrate good thermosensitivity and a three-dimensional network structure, with sustained release effects even after the addition of model drugs.

MARINE LIFE SCIENCE & TECHNOLOGY (2022)

Article Materials Science, Biomaterials

Injectable, self-healing, antibacterial, and hemostatic N,O-carboxymethyl chitosan/oxidized chondroitin sulfate composite hydrogel for wound dressing

Hongbin Li et al.

Summary: This work reports the development of an injectable, self-healing, antibacterial, hemostatic, and biocompatible hydrogel derived from the hybrid of N,O-carboxymethyl chitosan and oxidized chondroitin sulfate, which does not require any chemical crosslinking. The hydrogel exhibited excellent in vivo hemostatic performance and low cell toxicity, making it a promising wound dressing material.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Instruments & Instrumentation

Improving sciatic nerve regeneration by using alginate/chitosan hydrogel containing berberine

Majid Rahmati et al.

Summary: Peripheral nerve injuries caused by trauma can lead to pain and disability in patients. Berberine, with its various properties, can be used to enhance peripheral nerve injuries. The study demonstrated the positive effect of berberine-containing alginate/chitosan hydrogel on the regeneration of the sciatic nerve, indicating its potential therapeutic value in treating peripheral nerve injuries.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2021)

Article Biochemistry & Molecular Biology

Polysaccharide-Based Supramolecular Hydrogel for Efficiently Treating Bacterial Infection and Enhancing Wound Healing

Jing Wang et al.

Summary: Supramolecular hydrogels are highly biocompatible materials that show outstanding capabilities in drug loading through electrostatic interactions and host-guest inclusion. Biological experiments demonstrate that these hydrogels exhibit strong antibacterial effects and promote wound healing efficiently.

BIOMACROMOLECULES (2021)

Article Chemistry, Applied

Preparation, characterization and antioxidant activity of protocatechuic acid grafted carboxymethyl chitosan and its hydrogel

Chao Xu et al.

Summary: In this study, protocatechuic acid was grafted onto carboxymethyl chitosan to enhance antioxidant effect, where the conjugates showed improved radical scavenging activities and chelating activity. The prepared hydrogel exhibited sustained release of PCA-containing degraded fragment and protective effect against oxidative damage, suggesting its potential in drug release and tissue engineering applications.

CARBOHYDRATE POLYMERS (2021)

Article Biochemistry & Molecular Biology

Influence of pH-responsive compounds synthesized from chitosan and hyaluronic acid on dual-responsive (pH/temperature) hydrogel drug delivery systems of Cortex Moutan

Sudipta Chatterjee et al.

Summary: The study utilized polysaccharide-based pH-responsive compounds to enhance the pH stability and mechanical properties of PF127-based drug delivery systems, resulting in improved drug release behavior. Morphological analysis also showed better structures in the systems.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Materials Science, Biomaterials

Preparation of a recombinant collagen-peptide (RHC)-conjugated chitosan thermosensitive hydrogel for wound healing

Aipeng Deng et al.

Summary: Thermoresponsive hydrogels formed by conjugating recombinant human collagen-peptide (RHC) with chitosan exhibit lower gelation temperature and superior mechanical strength, showing good biocompatibility with cells and promoting cell infiltration, vessel formation, and wound healing. Overall, the use of RHC-chitosan hydrogels is a promising and effective therapeutic approach for burn wound treatment.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Engineering, Environmental

A novel self-healing polydopamine-functionalized chitosan-arginine hydrogel with enhanced angiogenic and antibacterial activities for accelerating skin wound healing

Zhixin Ling et al.

Summary: A self-healing hydrogel with angiogenic and antibacterial properties was developed for skin wound repair in this study. The hydrogel exhibited good mechanical properties and biocompatibility, accelerating wound healing and reducing scar formation.

CHEMICAL ENGINEERING JOURNAL (2021)

Review Biochemistry & Molecular Biology

Advancement on modification of chitosan biopolymer and its potential applications

Nabel A. Negm et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Review Biochemistry & Molecular Biology

Chitosan Derivatives and Their Application in Biomedicine

Wenqian Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Materials Science, Biomaterials

In vitro and in vivo evaluation of 3D biodegradable thermo/pH sensitive sol-gel reversible hydroxybutyl chitosan hydrogel

Jingjing Li et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Article Biophysics

The effect of form of carboxymethyl-chitosan dressings on biological properties in wound healing

Dong Wang et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2020)

Review Chemistry, Multidisciplinary

Chitosan hydrogels for sustained drug delivery

S. Peers et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Biochemistry & Molecular Biology

Chitosan and Cellulose-Based Hydrogels for Wound Management

Sibusiso Alven et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Nutrition & Dietetics

Glutamine in Burn Injury

Paul E. Wischmeyer

NUTRITION IN CLINICAL PRACTICE (2019)

Article Biochemistry & Molecular Biology

A natural cordycepin/chitosan complex hydrogel with outstanding self-healable and wound healing properties

Ruru Song et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Biochemistry & Molecular Biology

Enhanced properties of injectable chitosan-based thermogelling hydrogels by silk fibroin and longan seed extract for bone tissue engineering

Porntipa Pankongadisak et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Polymer Science

Hydrogel wound dressings based on chitosan and xyloglucan: Development and characterization

Diana M. Martinez-Ibarra et al.

JOURNAL OF APPLIED POLYMER SCIENCE (2019)

Review Chemistry, Applied

Chitosan based hydrogels and their applications for drug delivery in wound dressings: A review

Hamid Hamedi et al.

CARBOHYDRATE POLYMERS (2018)

Review Chemistry, Organic

Bioactivity of Chitosan and its Derivatives

Celine Laroche et al.

CURRENT ORGANIC CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

Amino acid-grafted and N-acylated chitosan thiomers: Construction of 3D bio-scaffolds for potential cartilage repair applications

Fernanda G. L. Medeiros Borsagli et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Review Polymer Science

Chitosan and Its Derivatives for Application in Mucoadhesive Drug Delivery Systems

Twana Mohammed M. Ways et al.

POLYMERS (2018)

Review Pharmacology & Pharmacy

Controlled local drug delivery strategies from chitosan hydrogels for wound healing

Lisa Elviri et al.

EXPERT OPINION ON DRUG DELIVERY (2017)

Article Chemistry, Applied

Thiolated chitosan micelles: Highly mucoadhesive drug carriers

Arshad Mahmood et al.

CARBOHYDRATE POLYMERS (2017)

Review Polymer Science

Biomedical applications of hydrogels: A review of patents and commercial products

Enrica Calo et al.

EUROPEAN POLYMER JOURNAL (2015)

Article Biochemistry & Molecular Biology

Preparation and characterization of N-benzoyl-O-acetyl-chitosan

Jinping Cai et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2015)

Article Pharmacology & Pharmacy

A thermo- and pH-sensitive hydrogel composed of quaternized chitosan/glycerophosphate

Jie Wu et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)

Article Medicine, Research & Experimental

L-Arginine and L-Lysine stimulation on cultured human osteoblasts

P Torricelli et al.

BIOMEDICINE & PHARMACOTHERAPY (2002)