☆ 4.7 Article

STAT6 gain-of-function variant exacerbates multiple allergic symptoms

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Editorial Material Allergy

Eosinophilic gastrointestinal diseases make a name for themselves: A new consensus statement with updated nomenclature

Benjamin L. Wright et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)

添加到收藏夹

Article Allergy

Inborn errors of immunity: Recent progress

Neha Seth et al.

Summary: Recent advances in the field of inborn errors of immunity (IEIs) have shown progress in disease mechanisms, diagnosis, and management. New gene defects affecting the immune response have been identified, along with advancements in immunopathogenesis. Effective treatment methods have been proven, but the COVID-19 pandemic has impacted patients with IEIs to varying degrees.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

添加到收藏夹

Review Allergy

JAK-STAT signaling in human disease: From genetic syndromes to clinical inhibition

Yiming Luo et al.

Summary: The JAK-STAT pathway is recognized as a central mediator of human physiological processes, with genomic sequencing leading to the discovery of clinical syndromes caused by mutations in JAK and STAT genes. Additionally, the therapeutic use of JAK inhibitors has expanded to include various diseases, with clinical studies providing mechanistic insights and improving patient care.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

添加到收藏夹

Review Allergy

Inborn Error of Immunity or Atopic Dermatitis: When to be Concerned and How to Investigate

Pia-Charlotte Stadler et al.

Summary: Atopic dermatitis may mask inborn errors of immunity, leading to different management and prognosis. Patients with IEIs may present with additional red flags that warrant clinical suspicion. Through various tests, clinicians can determine whether patients with eczematous skin lesions and elevated serum IgE levels should be referred to an immunologist for a comprehensive immunological work-up.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

添加到收藏夹

Editorial Material Allergy

New insights into human atopic dermatitis provided by mouse models

Kenji Matsumoto et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

添加到收藏夹

Article Allergy

Inborn errors of immunity manifesting as atopic disorders

Maryam Vaseghi-Shanjani et al.

Summary: Inborn errors of immunity are known for increasing susceptibility to infections, but allergic inflammation and other immune dysregulation types are common in these patients. Primary atopic disorders (PADs) is a term coined recently to describe heritable monogenic allergic disorders. Recognizing PADs is crucial for providing informed therapeutic options and improving patient outcomes through precision-based therapy targeting the underlying molecular defect.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

添加到收藏夹

Review Allergy

Inborn errors of immunity with eosinophilia

Keisuke Okamoto et al.

Summary: Monogenic diseases of the immune system, also known as inborn errors of immunity (IEIs), are caused by single-gene mutations resulting in immune deficiency and dysregulation. IEIs can predispose individuals to infectious diseases, cancer, and various immune disorders. IEIs with eosinophilia provide insights into human immunity and the pathogenesis of allergic diseases.

ALLERGOLOGY INTERNATIONAL (2021)

添加到收藏夹

Review Dermatology

The IL-4/IL-13 axis in skin fibrosis and scarring: mechanistic concepts and therapeutic targets

Julie K. Nguyen et al.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2020)

添加到收藏夹

Article Hematology

Selective loss of function variants in IL6ST cause Hyper-IgE syndrome with distinct impairments of T-cell phenotype and function

Tala Shahin et al.

HAEMATOLOGICA (2019)

添加到收藏夹

Article Allergy

Advances in asthma and allergic disease genetics: Is bigger always better?

Nathan Schoettler et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

添加到收藏夹

Review Immunology

Primary atopic disorders

Jonathan J. Lyons et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

添加到收藏夹

Review Allergy

Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases

Mubeccel Akdis et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

添加到收藏夹

Article Biochemical Research Methods

CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites

Yuki Naito et al.

BIOINFORMATICS (2015)

添加到收藏夹

Article Hematology

Activating STAT6 mutations in follicular lymphoma

Mehmet Yildiz et al.

BLOOD (2015)

添加到收藏夹

Article Immunology

B-cell-intrinsic STAT6 signaling controls germinal center formation

Adriana Turqueti-Neves et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2014)

添加到收藏夹

Article Immunology

Epithelial Cell-Derived IL-25, but Not Th17 Cell-Derived IL-17 or IL-17F, Is Crucial for Murine Asthma

Maho Suzukawa et al.

JOURNAL OF IMMUNOLOGY (2012)

添加到收藏夹

Article Biochemistry & Molecular Biology

Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity

Huihui Chen et al.

CELL (2011)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.