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Traditional vs. Microfluidic Synthesis of ZnO Nanoparticles

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MDPI
DOI: 10.3390/ijms24031875

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microfluidics; zinc oxide; challenges; nanoparticles; polydimethylsiloxane (PDMS)

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Microfluidics enables precise synthesis of micro-/nanostructures, with a wide range of applications in bioengineering and medicine. This review article compares traditional and microfluidic synthesis methods of zinc oxide (ZnO) in terms of particle size distribution, morphology, applications, reaction parameters, reagents, and device materials. It discusses how microfluidic approaches can overcome challenges faced by traditional synthesis methods, such as synthesis precision, bulk materials, and reproducibility.
Microfluidics provides a precise synthesis of micro-/nanostructures for various applications, including bioengineering and medicine. In this review article, traditional and microfluidic synthesis methods of zinc oxide (ZnO) are compared concerning particle size distribution, morphology, applications, reaction parameters, used reagents, and microfluidic device materials. Challenges of traditional synthesis methods are reviewed in a manner where microfluidic approaches may overcome difficulties related to synthesis precision, bulk materials, and reproducibility.

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