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Da Xu et al.
CELL REPORTS (2022)
Structural Analysis of Cholesterol Binding and Sterol Selectivity by ABCG5/G8
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JOURNAL OF MOLECULAR BIOLOGY (2022)
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Cholesterol Binds in a Reversed Orientation to TCRβ-TM in Which Its OH Group is Localized to the Center of the Lipid Bilayer
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Plasma Membrane Lipids: An Important Binding Site for All Lipoprotein Classes
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Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies
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Molecular basis of cholesterol efflux via ABCG subfamily transporters
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Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5
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Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level
Douglas J. Kenny et al.
CELL HOST & MICROBE (2020)
Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition
Ching-Shin Huang et al.
SCIENCE ADVANCES (2020)
Picky ABCG5/G8 and promiscuous ABCG2-a tale of fatty diets and drug toxicity
Narakorn Khunweeraphong et al.
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Structural snapshot of the cholesterol-transport ATP-binding cassette proteins
Bala M. Xavier et al.
BIOCHEMISTRY AND CELL BIOLOGY (2019)
HDL and Reverse Cholesterol Transport Basic Mechanisms and Their Roles in Vascular Health and Disease
Mireille Ouimet et al.
CIRCULATION RESEARCH (2019)
The extracellular gate shapes the energy profile of an ABC exporter
Cedric A. J. Hutter et al.
NATURE COMMUNICATIONS (2019)
The ABCG2 multidrug transporter is a pump gated by a valve and an extracellular lid
Narakorn Khunweeraphong et al.
NATURE COMMUNICATIONS (2019)
Cholesterol Flip-Flop in Heterogeneous Membranes
Ruo-Xu Gu et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2019)
Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1
Atsushi Kodan et al.
NATURE COMMUNICATIONS (2019)
Is ABCA1 a lipid transfer protein?
Michael C. Phillips
JOURNAL OF LIPID RESEARCH (2018)
Temporary sequestration of cholesterol and phosphatidylcholine within extracellular domains of ABCA1 during nascent HDL generation
Masato Ishigami et al.
SCIENTIFIC REPORTS (2018)
ABCA1 (ATP-Binding Cassette Transporter A1) Mediates ApoA-I (Apolipoprotein A-I) and ApoA-I Mimetic Peptide Mobilization of Extracellular Cholesterol Microdomains Deposited by Macrophages
Xueting Jin et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)
Crystal structure of the human sterol transporter ABCG5/ABCG8
Jyh-Yeuan Lee et al.
NATURE (2016)
Mechanistic diversity in ATP-binding cassette (ABC) transporters
Kaspar P. Locher
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Mechanistic diversity in ATP-binding cassette (ABC) transporters
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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas
Jens P. Andersen et al.
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ABCA1 and nascent HDL biogenesis
Shuhui Wang et al.
BIOFACTORS (2014)
ABCG1-mediated generation of extracellular cholesterol microdomains
Sebastian R. Freeman et al.
JOURNAL OF LIPID RESEARCH (2014)
Molecular Mechanisms for Biliary Phospholipid and Drug Efflux Mediated by ABCB4 and Bile Salts
Shin-ya Morita et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Characterization of the Role of a Highly Conserved Sequence in ATP Binding Cassette Transporter G (ABCG) Family in ABCG1 Stability, Oligomerization, and Trafficking
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BIOCHEMISTRY (2013)
ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin
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JOURNAL OF LIPID RESEARCH (2013)
The effect of ABCG1 deficiency on atherosclerotic lesion development in LDL receptor knockout mice depends on the stage of atherogenesis
Illiana Meurs et al.
ATHEROSCLEROSIS (2012)
Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein
Carlos L. J. Vrins et al.
JOURNAL OF LIPID RESEARCH (2012)
The ABCG family of membrane-associated transporters: you don't have to be big to be mighty
Ian D. Kerr et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Deletion of ABCA1 and ABCG1 Impairs Macrophage Migration Because of Increased Rac1 Signaling
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CIRCULATION RESEARCH (2011)
The ABC of ABCs: multidrug resistance and genetic diseases
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NPC2 Regulates Biliary Cholesterol Secretion via Stimulation of ABCG5/G8-Mediated Cholesterol Transport
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GASTROENTEROLOGY (2011)
Extracellular cholesterol-rich microdomains generated by human macrophages and their potential function in reverse cholesterol transport
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JOURNAL OF LIPID RESEARCH (2010)
ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis
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JOURNAL OF LIPID RESEARCH (2010)
The role of membrane cholesterol in determining bile acid cytotoxicity and cytoprotection of ursodeoxycholic acid
Yong Zhou et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
The liquid-ordered phase in membranes
Peter J. Quinn et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
ABC transporters: the power to change
Douglas C. Rees et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1
Osamu Sano et al.
JOURNAL OF LIPID RESEARCH (2007)
ABCA1-induced cell surface binding sites for ApoA-I
Charulatha Vedhachalam et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetirnibe
Ryan E. Temel et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Structure and function of ABC transporters: the ATP switch provides flexible control
Kenneth J. Linton et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
ATP-binding cassette, subfamily G (ABCG family)
Hiroyuki Kusuhara et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice
Astrid Kosters et al.
JOURNAL OF LIPID RESEARCH (2006)
Calreticulin facilitates the cell surface expression of ABCG5/G8
Tsukasa Okiyoneda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Cholesterol and the interaction of proteins with membrane domains
Richard M. Epand
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High-speed screening and QSAR analysis of human ATP-binding cassette transporter ABCB11 (bile salt export pump) to predict drug-induced intrahepatic cholestasis
Hiroyuki Hirano et al.
MOLECULAR PHARMACEUTICS (2006)
ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I
IC Gelissen et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Expression of ABCG1, but not ABCA1, correlates with cholesterol release by cerebellar astroglia
B Karten et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8
DW Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
ABC transporter architecture and regulatory roles of accessory domains
E Biemans-Oldehinkel et al.
FEBS LETTERS (2006)
ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins
AM Vaughan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A thermodynamic analysis of charged mixed micelles in water
H Maeda
JOURNAL OF PHYSICAL CHEMISTRY B (2005)
ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile
S Langheim et al.
JOURNAL OF LIPID RESEARCH (2005)
ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation
MA Kennedy et al.
CELL METABOLISM (2005)
Properties of P-glycoprotein with mutations in the catalytic carboxylate glutamate residues
G Tombline et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Lipid rafts in epithelial brush borders: atypical membrane microdomains with specialized functions
EM Danielsen et al.
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Role of carboxylate residues adjacent to the conserved core walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1)
LF Payen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Importance of the conserved Walker B glutamate residues, 556 and 1201, for the completion of the catalytic cycle of ATP hydrolysis by human P-glycoprotein (ABCB1)
ZE Sauna et al.
BIOCHEMISTRY (2002)
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption
MH Lee et al.
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Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
KE Berge et al.
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Lipid rafts and signal transduction
K Simons et al.
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