Development of Cell Therapies for Renal Disease and Regenerative Medicine

The incidence of renal disease is gradually increasing worldwide, and this condition has become a major public health problem because it is a trigger for many other chronic diseases. Cell therapies using multipotent mesenchymal stromal cells, hematopoietic stem cells, macrophages, and other cell types have been used to induce regeneration and provide a cure for acute and chronic kidney disease in experimental models. This review describes the advances in cell therapy protocols applied to acute and chronic kidney injuries and the attempts to apply these treatments in a clinical setting.

Automated summary

The incidence of renal disease is increasing worldwide and has become a significant public health issue. Cell therapies have been used in experimental models to induce regeneration and treat acute and chronic kidney diseases. Efforts have been made to apply these treatments in a clinical setting.