相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Redesigning therapies for pantothenate kinase-associated neurodegeneration
Muhammad I. Munshi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2022)
PI3K drives the de novo synthesis of coenzyme A from vitamin B5
Christian C. Dibble et al.
NATURE (2022)
High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development
Shalev Gihaz et al.
STRUCTURE (2022)
Exploring Yeast as a Study Model of Pantothenate Kinase-Associated Neurodegeneration and for the Identification of Therapeutic Compounds
Camilla Ceccatelli Berti et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations
Giulia di Punzio et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Rational Design of Novel Therapies for Pantothenate Kinase-Associated Neurodegeneration
Nivedita Thakur et al.
MOVEMENT DISORDERS (2021)
A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction
Chitra Subramanian et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)
Mitochondrial Dysfunction, Oxidative Stress and Neuroinflammation in Neurodegeneration with Brain Iron Accumulation (NBIA)
Isabel Hinarejos et al.
ANTIOXIDANTS (2020)
Human pantothenate kinase 4 is a pseudo-pantothenate kinase
Jiangwei Yao et al.
PROTEIN SCIENCE (2019)
Iron accumulation causes impaired myogenesis correlated with MAPK signaling pathway inhibition by oxidative stress
Yasumasa Ikeda et al.
FASEB JOURNAL (2019)
4′-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN
Suh Young Jeong et al.
EMBO MOLECULAR MEDICINE (2019)
CoA-dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases
Roald A. Lambrechts et al.
EMBO MOLECULAR MEDICINE (2019)
The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors
Joy E. Chiu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Mitochondrial acyl carrier protein (ACP) at the interface of metabolic state sensing and mitochondrial function
Ali J. Masud et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
Role of mitochondrial ROS in the brain: from physiology to neurodegeneration
Plamena R. Angelova et al.
FEBS LETTERS (2018)
A therapeutic approach to pantothenate kinase associated neurodegeneration
Lalit Kumar Sharma et al.
NATURE COMMUNICATIONS (2018)
iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease
Charles Arber et al.
PLOS ONE (2017)
The antimalarial activity of the pantothenamide α-PanAm is via inhibition of pantothenate phosphorylation
Joy E. Chiu et al.
SCIENTIFIC REPORTS (2017)
Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration
Daniel I. Orellana et al.
EMBO MOLECULAR MEDICINE (2016)
A family of metal-dependent phosphatases implicated in metabolite damage-control
Lili Huang et al.
NATURE CHEMICAL BIOLOGY (2016)
Extracellular 4′-phosphopantetheine is a source for intracellular coenzyme A synthesis
Balaji Srinivasan et al.
NATURE CHEMICAL BIOLOGY (2015)
Physiological roles of the pantothenate kinases
Lorraine E. Dansie et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2014)
Malfunctioning of the Iron-Sulfur Cluster Assembly Machinery in Saccharomyces cerevisiae Produces Oxidative Stress via an Iron-Dependent Mechanism, Causing Dysfunction in Respiratory Complexes
Mauricio Gomez et al.
PLOS ONE (2014)
Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms
Sonia Levi et al.
FRONTIERS IN PHARMACOLOGY (2014)
The interplay between iron accumulation, maochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders
Pamela J. Urrutia et al.
FRONTIERS IN PHARMACOLOGY (2014)
Compartmentalization of Mammalian Pantothenate Kinases
Adolfo Alfonso-Pecchio et al.
PLOS ONE (2012)
Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration
Anil Rana et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1
Judith Olzhausen et al.
CURRENT GENETICS (2009)
Functional study in a yeast model of a novel succinate dehydrogenase subunit B gene germline missense mutation (C191Y) diagnosed in a patient affected by a glomus tumor
Paola Goffrini et al.
HUMAN MOLECULAR GENETICS (2009)
Pantothenate kinase-associated neurodegeneration: insights from a Drosophila model
Zhihao Wu et al.
HUMAN MOLECULAR GENETICS (2009)
Altered neuronal mitochondrial coenzyme a synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2
PT Kotzbauer et al.
JOURNAL OF NEUROSCIENCE (2005)
Global analysis of protein localization in budding yeast
WK Huh et al.
NATURE (2003)
An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria
K Hörtnagel et al.
HUMAN MOLECULAR GENETICS (2003)
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome
B Zhou et al.
NATURE GENETICS (2001)