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Sigma-1 receptor knockout mice display a depressive-like phenotype
Valentina Sabino et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
The sigma1 receptor interacts with N-alkyl amines and endogenous sphingolipids
Subramaniam Ramachandran et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology
Fenghua Zeng et al.
EXPERIMENTAL CELL RESEARCH (2009)
Stimulation of Sigma-1 receptor signaling by dehydroepiandrosterone ameliorates pressure overload-induced hypertrophy and dysfunctions in ovariectomized rats
Md. Shenuarin Bhuiyan et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2009)
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice
Haiyun Ling et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
MAM: more than just a housekeeper
Teruo Hayashi et al.
TRENDS IN CELL BIOLOGY (2009)
Safety and efficacy of sertraline for depression in patients with CHF (SADHART-CHF): A randomized, double-blind, placebo-controlled trial of sertraline for major depression with congestive heart failure
Wei Jiang et al.
AMERICAN HEART JOURNAL (2008)
Epidermal Growth Factor Receptor Signaling in the Kidney Key Roles in Physiology and Disease
Wynand B. W. H. Melenhorst et al.
HYPERTENSION (2008)
Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the σ-1 receptor
Arindam Pal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
σ-1 Receptor Modulation of Acid-Sensing Ion Channel a (ASIC1a) and ASIC1a-Induced Ca2+ Influx in Rat Cortical Neurons
Yelenis Herrera et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
sigma-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, Bax levels, and caspase-3 activation
Kissaou T. Tchedre et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines
Christopher P. Palmer et al.
CANCER RESEARCH (2007)
IRE1 signaling affects cell fate during the unfolded protein response
Jonathan H. Lin et al.
SCIENCE (2007)
Sigma-1 receptor chaperones at the ER-Mitochondrion interface regulate Ca2+ signaling and cell survival
Teruo Hayashi et al.
CELL (2007)
Voltage-gated ion channels, new targets in anti-cancer research
Le Guennec Jean-Yves et al.
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY (2007)
Rubiscolin-6, a δ opioid peptide derived from spinach Rubisco, has anxiolytic effect via activating σ1, and dopamine D1 receptors
Hajime Hirata et al.
PEPTIDES (2007)
Signal integration in the endoplasmic reticulum unfolded protein response
David Ron et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2
Sufang Yang et al.
ANESTHESIA AND ANALGESIA (2007)
HIF-1α contributes to tumour-selective killing by the sigma receptor antagonist rimcazole
M. Achison et al.
ONCOGENE (2007)
The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus
Marzia Martina et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
The anti-amnesic and neuroprotective effects of donepezil against amyloid β25-35 peptide-induced toxicity in mice involve an interaction with the σ1 receptor
J. Meunier et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Expression, subcellular localization, and regulation of sigma receptor in retinal Muller cells
Guoliang Jiang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
The effect of chronic co-administration of fluvoxamine and haloperidol compared to clozapine on the GABA system in the rat frontal cortex
Yael Chertkow et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2006)
hERG potassium channels and cardiac arrhythmia
MC Sanguinetti et al.
NATURE (2006)
Sertraline versus fluvoxamine in the treatment of elderly patients with major depression - A double-blind, randomized trial
D Rossini et al.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2005)
Involvement of sigma (σ) receptors in the acute actions of methamphetamine:: Receptor binding and behavioral studies
EC Nguyen et al.
NEUROPHARMACOLOGY (2005)
σ receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons
HL Zhang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Relationship between release of platelet/endothelial biomarkers and plasma levels of sertraline and N-desmethylsertraline in acute coronary syndrome patients receiving SSRI treatment for depression
VL Serebruany et al.
AMERICAN JOURNAL OF PSYCHIATRY (2005)
Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a
O Yermolaieva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
ER chaperone functions during normal and stress conditions
YJ Ma et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2004)
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction - Possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis
K Okada et al.
CIRCULATION (2004)
σ-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells:: Potential relation to lipid raft reconstitution
M Takebayashi et al.
SYNAPSE (2004)
Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo
BA Spruce et al.
CANCER RESEARCH (2004)
Understanding the molecular mechanism of sigma-1 receptors: Towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction
TP Su et al.
CURRENT MEDICINAL CHEMISTRY (2003)
Generation and phenotypic analysis of sigma receptor type I (σ1) knockout mice
F Langa et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events - The Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) platelet substudy
VL Serebruany et al.
CIRCULATION (2003)
σ-1 receptors (σ1 binding sites) form raft-like microdomains and target lipid droplets on the endoplasmic reticulum:: Roles in endoplasmic reticulum lipid compartmentalization and export
T Hayashi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Intracellular dynamics of σ-1 receptors (σ1 binding sites) in NG108-15 cells
T Hayashi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Influence of depression and effect of treatment with sertraline on quality of life after hospitalization for acute coronary syndrome
JR Swenson et al.
AMERICAN JOURNAL OF CARDIOLOGY (2003)
The sigma receptor as a ligand-regulated auxiliary potassium channel subunit
E Aydar et al.
NEURON (2002)
Sigma receptors: from discovery to highlights of their implications in the cardiovascular system
L Monassier et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2002)
Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor
P Seth et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2001)
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