相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine
Shao-Ming Wang et al.
AUTOPHAGY (2023)
PINK1-PRKN mediated mitophagy: differences between in vitro and in vivo models
Rui Han et al.
AUTOPHAGY (2023)
Safety and efficacy of fluvoxamine in COVID-19 ICU patients: An open label, prospective cohort trial with matched controls
Martina Calusic et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2022)
Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association
Connie W. Tsao et al.
CIRCULATION (2022)
The molecular role of Sigmar1 in regulating mitochondrial function through mitochondrial localization in cardiomyocytes
Chowdhury S. Abdullah et al.
MITOCHONDRION (2022)
Mechanisms of action of fluvoxamine for COVID-19: a historical review
Yaeko Hashimoto et al.
MOLECULAR PSYCHIATRY (2022)
Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial
Gilmar Reis et al.
LANCET GLOBAL HEALTH (2022)
Intracellular dynamics of the Sigma-1 receptor observed with super-resolution imaging microscopy
Sergei Kopanchuk et al.
PLOS ONE (2022)
Oxycodone protects cardiac microvascular endothelial cells against ischemia/reperfusion injury by binding to Sigma-1 Receptor
Meihua Ji et al.
BIOENGINEERED (2022)
Epidemiology of chronic kidney disease: an update 2022
Csaba P. Kovesdy
KIDNEY INTERNATIONAL SUPPLEMENTS (2022)
PRE-084 ameliorates adenine-induced renal fibrosis in rats
C. V. Haritha et al.
TISSUE & CELL (2022)
Activation of the sigma-1 receptor exerts cardioprotection in a rodent model of chronic heart failure by stimulation of angiogenesis
Xin Zhao et al.
MOLECULAR MEDICINE (2022)
Repurposing of CNS drugs to treat COVID-19 infection: targeting the sigma-1 receptor
Kenji Hashimoto
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2021)
The Sigma-1 receptor is an ER-localized type II membrane protein
Neeraj Sharma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
The Emerging Role of BDNF/TrkB Signaling in Cardiovascular Diseases
Peng-Zhou Hang et al.
LIFE-BASEL (2021)
Prospective Cohort of Fluvoxamine for Early Treatment of Coronavirus Disease 19
David Seftel et al.
OPEN FORUM INFECTIOUS DISEASES (2021)
Receptor Tyrosine Kinases and Their Signaling Pathways as Therapeutic Targets of Curcumin in Cancer
Sareshma Sudhesh Dev et al.
FRONTIERS IN PHARMACOLOGY (2021)
Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating
Jose Alexandre Salerno et al.
PEERJ (2021)
A deleterious interplay between endoplasmic reticulum stress and its functional linkage to mitochondria in nephrolithiasis
Minu Sharma et al.
FREE RADICAL BIOLOGY AND MEDICINE (2021)
Mortality Risk Among Patients With COVID-19 Prescribed Selective Serotonin Reuptake Inhibitor Antidepressants
Tomiko Oskotsky et al.
JAMA NETWORK OPEN (2021)
The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains
Vladimir Zhemkov et al.
ELIFE (2021)
Therapeutic Inhibition of Acid-Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury
Meredith A. Redd et al.
CIRCULATION (2021)
Sigmar1's Molecular, Cellular, and Biological Functions in Regulating Cellular Pathophysiology
Richa Aishwarya et al.
FRONTIERS IN PHYSIOLOGY (2021)
Sigma-1 Receptor Promotes Mitochondrial Bioenergetics by Orchestrating ER Ca2+ Leak during Early ER Stress
Zhanat Koshenov et al.
METABOLITES (2021)
Cardiac fibrosis
Nikolaos G. Frangogiannis
CARDIOVASCULAR RESEARCH (2021)
Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder
Yan Guo et al.
PSYCHOPHARMACOLOGY (2021)
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
David E. Gordon et al.
NATURE (2020)
Renal expression of sigma 1 receptors in diabetic rats
Ivana Milardovic et al.
ACTA HISTOCHEMICA (2020)
Chronic stimulation of the sigma-1 receptor ameliorates ventricular ionic and structural remodeling in a rodent model of depression
Xiuhuan Chen et al.
LIFE SCIENCES (2020)
Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure
Toshihiro Yamaguchi et al.
NATURE COMMUNICATIONS (2020)
Association Between Depressive Symptoms and Incident Cardiovascular Diseases
Eric L. Harshfield et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)
Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19 A Randomized Clinical Trial
Eric J. Lenze et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)
Sex-dependent mechanisms involved in renal tolerance to ischemia-reperfusion: Role of inflammation and histone H3 citrullination
Zesergio Melo et al.
TRANSPLANT IMMUNOLOGY (2020)
Cardiovascular Manifestations of COVID-19 Infection
Ajit Magadum et al.
CELLS (2020)
Methamphetamine induces cardiomyopathy by Sigmar1 inhibition-dependent impairment of mitochondrial dynamics and function
Chowdhury S. Abdullah et al.
COMMUNICATIONS BIOLOGY (2020)
Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases
Na Ye et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Repurposing Sigma-1 Receptor Ligands for COVID-19 Therapy?
Jose Miguel Vela
FRONTIERS IN PHARMACOLOGY (2020)
Sigma-1 receptor chaperones rescue nucleocytoplasmic transport deficit seen in cellular and Drosophila ALS/FTD models
Pin-Tse Lee et al.
NATURE COMMUNICATIONS (2020)
SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance
Huan Yang et al.
AUTOPHAGY (2019)
Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies A Scientific Statement From the American Heart Association
Janani Rangaswami et al.
CIRCULATION (2019)
Unfolded Protein Response as a Therapeutic Target in Cardiovascular Disease
Guangyu Zhang et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2019)
The Potential for microRNA Therapeutics and Clinical Research
Johora Hanna et al.
FRONTIERS IN GENETICS (2019)
A New Pharmacophore Model for the Design of Sigma-1 Ligands Validated on a Large Experimental Dataset
Rosalia Pascual et al.
FRONTIERS IN PHARMACOLOGY (2019)
Methamphetamine Use and Cardiovascular Disease In Search of Answers
Christopher G. Kevil et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)
Neuronal Sigma-1 Receptors: Signaling Functions and Protective Roles in Neurodegenerative Diseases
Daniel A. Ryskamp et al.
FRONTIERS IN NEUROSCIENCE (2019)
The Sigma-1 Receptor in Cellular Stress Signaling
Teruo Hayashi
FRONTIERS IN NEUROSCIENCE (2019)
Examination of Cardioprotective Effects of Fabomotizole Hydrochloride in Translational Rat Model of Chronic Heart Failure
S. A. Kryzhanovskii et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2019)
Chronic inhibition of the sigma-1 receptor exacerbates atrial fibrillation susceptibility in rats by promoting atrial remodeling
Tianxin Ye et al.
LIFE SCIENCES (2019)
The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism
Xin Liu et al.
FRONTIERS IN PHYSIOLOGY (2019)
The endoplasmic reticulum (ER) chaperone BiP is a master regulator of ER functions: Getting by with a little help from ERdj friends
Kristine Faye R. Pobre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Imbalance of ER and Mitochondria Interactions: Prelude to Cardiac Ageing and Disease?
Jin Li et al.
CELLS (2019)
High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation
Michael Rehman et al.
JCI INSIGHT (2019)
Sigma-1 Receptor Stimulation with PRE-084 Ameliorates Myocardial Ischemia-Reperfusion Injury in Rats
Qi-Jun Gao et al.
CHINESE MEDICAL JOURNAL (2018)
The role of Sigma-1 receptor in sex-specific heat shock response in an experimental rat model of renal ischaemia/reperfusion injury
Adam Hosszu et al.
TRANSPLANT INTERNATIONAL (2018)
Cannabinoids, the Heart of the Matter
Naghum Alfulaij et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)
Chronic stimulation of the sigma-1 receptor ameliorates autonomic nerve dysfunction and atrial fibrillation susceptibility in a rat model of depression
Xin Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)
Structural basis for σ1 receptor ligand recognition
Hayden R. Schmidt et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics
Chowdhury S. Abdullah et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)
Endoplasmic reticulum stress is activated in post-ischemic kidneys to promote chronic kidney disease
Shaoqun Shu et al.
EBIOMEDICINE (2018)
σ1-Receptor Agonism Protects against Renal Ischemia-Reperfusion Injury
Adam Hosszu et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
Escitalopram, a selective serotonin reuptake inhibitor, inhibits voltage-dependent K+(channels in coronary arterial smooth muscle cells
Han Sol Kim et al.
KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY (2017)
MicroRNA-297 promotes cardiomyocyte hypertrophy via targeting sigma-1 receptor
Qinxue Bao et al.
LIFE SCIENCES (2017)
THE σ1 RECEPTOR REGULATES ACCUMULATION OF GM1 GANGLIOSIDE-ENRICHED AUTOPHAGOSOMES IN ASTROCYTES
Rika Kasahara et al.
NEUROSCIENCE (2017)
The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission
Danielle O. Sambo et al.
NATURE COMMUNICATIONS (2017)
APEX2-enhanced electron microscopy distinguishes sigma-1 receptor localization in the nucleoplasmic reticulum
Timur A. Mavlyutov et al.
ONCOTARGET (2017)
The ALS-linked E102Q mutation in Sigma receptor-1 leads to ER stress-mediated defects in protein homeostasis and dysregulation of RNA-binding proteins
Alice Dreser et al.
CELL DEATH AND DIFFERENTIATION (2017)
Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases
Tzu-Yu Weng et al.
JOURNAL OF BIOMEDICAL SCIENCE (2017)
Sigmar1 regulates endoplasmic reticulum stress-induced C/EBP-homologous protein expression in cardiomyocytes
Shafiul Alam et al.
BIOSCIENCE REPORTS (2017)
Sigma-1 Receptor Modulates Neuroinflammation After Traumatic Brain Injury
Hui Dong et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2016)
Role of peripheral sigma-1 receptors in ischaemic pain: Potential interactions with ASIC and P2X receptors
S. G. Kwon et al.
EUROPEAN JOURNAL OF PAIN (2016)
Cocaine-Mediated Autophagy in Astrocytes Involves Sigma 1 Receptor, PI3K, mTOR, Atg5/7, Beclin-1 and Induces Type II Programed Cell Death
Lu Cao et al.
MOLECULAR NEUROBIOLOGY (2016)
Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation
Tina Garofalo et al.
AUTOPHAGY (2016)
Alternative splicing and cell survival: from tissue homeostasis to disease
Maria Paola Paronetto et al.
CELL DEATH AND DIFFERENTIATION (2016)
Cardiac Fibrosis The Fibroblast Awakens
Joshua G. Travers et al.
CIRCULATION RESEARCH (2016)
Molecular Mechanisms Involving Sigma-1 Receptor in Cell Apoptosis of BV-2 Microglial Cells Induced by Methamphetamine
Kai Shen et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2016)
Cannabinoid receptors in the kidney
Deanne H. Hryciw et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2016)
Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS
Seiji Watanabe et al.
EMBO MOLECULAR MEDICINE (2016)
Crystal structure of the human σ1 receptor
Hayden R. Schmidt et al.
NATURE (2016)
The sigma-1 receptor-zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury
Tzu-Chieh Su et al.
NEUROPHARMACOLOGY (2016)
The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems
Tsung-Ping Su et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and Disease
Yan Liang et al.
FRONTIERS IN PHARMACOLOGY (2016)
The σ1 Receptor Engages the Redox-Regulated HINT1 Protein to Bring Opioid Analgesia Under NMDA Receptor Negative Control
Maria Rodriguez-Munoz et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands
Ashish K. Mishra et al.
BIOCHEMICAL JOURNAL (2015)
Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria
Nino Natsvlishvili et al.
BMC BIOCHEMISTRY (2015)
Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration
Nathalie Bernard-Marissal et al.
BRAIN (2015)
Sex-related neurogenesis decrease in hippocampal dentate gyrus with depressive-like behaviors in sigma-1 receptor knockout mice
Sha Sha et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2015)
Solution NMR studies reveal the location of the second transmembrane domain of the human sigma-1 receptor
Jose Luis Ortega-Roldan et al.
FEBS LETTERS (2015)
Sigma 1 receptor regulates the oxidative stress response in primary retinal Muller glial cells via NRF2 signaling and system xc-, the Na+-independent glutamate-cystine exchanger
Jing Wang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells
Thomas D. B. MacVicar et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Heart failure induces changes in acid-sensing ion channels in sensory neurons innervating skeletal muscle
David D. Gibbons et al.
JOURNAL OF PHYSIOLOGY-LONDON (2015)
Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope
Shang-Yi A. Tsai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study
Glen L. Xiong et al.
PSYCHOSOMATIC MEDICINE (2015)
Long-Term Haloperidol Treatment Prolongs QT Interval and Increases Expression of Sigma 1 and IP3 Receptors in Guinea Pig Hearts
Tibor Stracina et al.
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Subcellular Localization of the Sigma-1 Receptor in Retinal Neurons - an Electron Microscopy Study
Timur A. Mavlyutov et al.
SCIENTIFIC REPORTS (2015)
Insights into the modulation of dopamine transporter function by amphetamine, orphenadrine, and cocaine binding
Mary Hongying Cheng et al.
FRONTIERS IN NEUROLOGY (2015)
CREB phosphorylation at Ser133 regulates transcription via distinct mechanisms downstream of cAMP and MAPK signalling
Shaista Naqvi et al.
BIOCHEMICAL JOURNAL (2014)
Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis
Hideaki Tagashira et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway
Zhao V. Wang et al.
CELL (2014)
Sigma receptor 1 modulates ER stress and Bcl2 in murine retina
Yonju Ha et al.
CELL AND TISSUE RESEARCH (2014)
The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases
Pilar Sanchez-Blazquez et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2014)
The Oligomeric States of the Purified Sigma-1 Receptor Are Stabilized by Ligands
Katarzyna A. Gromek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Predicting the Antinociceptive Efficacy of σ1 Receptor Ligands by a Novel Receptor Fluorescence Resonance Energy Transfer (FRET) Based Biosensor
Maricel Gomez-Soler et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
NMDA Receptors Are Upregulated and Trafficked to the Plasma Membrane after Sigma-1 Receptor Activation in the Rat Hippocampus
Mohan Pabba et al.
JOURNAL OF NEUROSCIENCE (2014)
Cocaine Disrupts Histamine H3 Receptor Modulation of Dopamine D1 Receptor Signaling: σ1-D1-H3 Receptor Complexes as Key Targets for Reducing Cocaine's Effects
Estefania Moreno et al.
JOURNAL OF NEUROSCIENCE (2014)
Accumulation of the sigma-1 receptor is common to neuronal nuclear inclusions in various neurodegenerative diseases
Yasuo Miki et al.
NEUROPATHOLOGY (2014)
Phase II Trial of the Sigma-1 Receptor Agonist Cutamesine (SA4503) for Recovery Enhancement After Acute Ischemic Stroke
Roman Urfer et al.
STROKE (2014)
Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances
J. T. Vollrath et al.
CELL DEATH & DISEASE (2014)
Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor
T. Omi et al.
CELL DEATH & DISEASE (2014)
Diverse regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes
Hideaki Tagashira et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Stimulation of σ1-receptor restores abnormal mitochondrial Ca2+ mobilization and ATP production following cardiac hypertrophy
Hideaki Tagashira et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Dynamic Interaction between Sigma-1 Receptor and Kv1.2 Shapes Neuronal and Behavioral Responses to Cocaine
Said Kourrich et al.
CELL (2013)
The Epidermal Growth Factor Receptor and Its Ligands in Cardiovascular Disease
Nader Makki et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Characterization of the Human Sigma-1 Receptor Chaperone Domain Structure and Binding Immunoglobulin Protein (BiP) Interactions
Jose Luis Ortega-Roldan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Brain Sigma-1 Receptor Stimulation Improves Mental Disorder and Cardiac Function in Mice With Myocardial Infarction
Koji Ito et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2013)
The σ-1 Receptor Interacts Directly with GluN1 But Not GluN2A in the GluN1/GluN2A NMDA Receptor
Dilshan Balasuriya et al.
JOURNAL OF NEUROSCIENCE (2013)
Role of epidermal growth factor receptor in acute and chronic kidney injury
Jinhua Tang et al.
KIDNEY INTERNATIONAL (2013)
Autophagosomes form at ER-mitochondria contact sites
Maho Hamasaki et al.
NATURE (2013)
Cocaine Inhibits Dopamine D2 Receptor Signaling via Sigma-1-D2 Receptor Heteromers
Gemma Navarro et al.
PLOS ONE (2013)
Sigma-1 Receptor Chaperone at the ER-Mitochondrion Interface Mediates the Mitochondrion-ER-Nucleus Signaling for Cellular Survival
Tomohisa Mori et al.
PLOS ONE (2013)
Sigma-1 Receptor Enhances Neurite Elongation of Cerebellar Granule Neurons via TrkB Signaling
Yuriko Kimura et al.
PLOS ONE (2013)
Sigma-1 receptor chaperone and brain-derived neurotrophic factor: Emerging links between cardiovascular disease and depression
Kenji Hashimoto
PROGRESS IN NEUROBIOLOGY (2013)
Brain-Derived Neurotrophic Factor Protects Against Cardiac Dysfunction After Myocardial Infarction via a Central Nervous System-Mediated Pathway
Sho Okada et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Sigma-1 receptor alters the kinetics of Kv1.3 voltage gated potassium channels but not the sensitivity to receptor ligands
Maho Kinoshita et al.
BRAIN RESEARCH (2012)
Decreased brain sigma-1 receptor contributes to the relationship between heart failure and depression
Koji Ito et al.
CARDIOVASCULAR RESEARCH (2012)
Health Status and Depression Remission in Patients With Chronic Heart Failure Patient-Reported Outcomes From the SADHART-CHF Trial
Glen L. Xiong et al.
CIRCULATION-HEART FAILURE (2012)
Sigma-1 Receptor Agonists as Therapeutic Drugs for Cognitive Impairment in Neuropsychiatric Diseases
Tomihisa Niitsu et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements
Arindam Pal et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
The Sigma-1 Receptor Binds to the Nav1.5 Voltage-gated Na+ Channel with 4-Fold Symmetry
Dilshan Balasuriya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Expression of a Truncated Form of the Endoplasmic Reticulum Chaperone Protein, σ1 Receptor, Promotes Mitochondrial Energy Depletion and Apoptosis
Norifumi Shioda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Signaling to Cardiac Hypertrophy: Insights from Human and Mouse RASopathies
Valentina Sala et al.
MOLECULAR MEDICINE (2012)
Sigma 1 receptor stimulation protects against oxidative damage through suppression of the ER stress responses in the human lens
Lixin Wang et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2012)
Sigma-1 Receptor Agonists Directly Inhibit NaV1.2/1.4 Channels
Xiao-Fei Gao et al.
PLOS ONE (2012)
Insights Into the Sigma-1 Receptor Chaperone's Cellular Functions: A Microarray Report
Shang-Yi Tsai et al.
SYNAPSE (2012)
Sigma-1 receptor chaperones regulate the secretion of brain-derived neurotrophic factor
Michiko Fujimoto et al.
SYNAPSE (2012)
The sigma-1 receptor: roles in neuronal plasticity and disease
Said Kourrich et al.
TRENDS IN NEUROSCIENCES (2012)
Characteristics of Depression Remission and Its Relation With Cardiovascular Outcome Among Patients With Chronic Heart Failure (from the SADHART-CHF Study)
Wei Jiang et al.
AMERICAN JOURNAL OF CARDIOLOGY (2011)
Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels
Molly Johannessen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Sigma-1Rs are upregulated via PERK/eIF2α/ATF4 pathway and execute protective function in ER stress
Teruhiko Mitsuda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection
M. D. Shenuarin Bhuiyan et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders
Teruo Hayashi et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
Sig1R Protein Regulates hERG Channel Expression through a Post-translational Mechanism in Leukemic Cells
David Crottes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
Roberto Bravo et al.
JOURNAL OF CELL SCIENCE (2011)
Cocaine Hijacks σ1 Receptor to Initiate Induction of Activated Leukocyte Cell Adhesion Molecule: Implication for Increased Monocyte Adhesion and Migration in the CNS
Honghong Yao et al.
JOURNAL OF NEUROSCIENCE (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
Sigma Receptor 1 Modulates Endoplasmic Reticulum Stress in Retinal Neurons
Yonju Ha et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Ceramide modulates HERG potassium channel gating by translocation into lipid rafts
Sindura B. Ganapathi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
σ1-Receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice
Hideaki Tagashira et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Demonstration of a Direct Interaction between σ-1 Receptors and Acid-Sensing Ion Channels
Stewart M. Carnally et al.
BIOPHYSICAL JOURNAL (2010)
Fluvoxamine pharmacokinetics in healthy elderly subjects and elderly patients with chronic heart failure
Rocco Orlando et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2010)
Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats
Md. Shenuarin Bhuiyan et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2010)
Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions
Md. Shenuarin Bhuiyan et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
Haloperidol increases expression of the inositol 1,4,5-trisphosphate receptors in rat cardiac atria, but not in ventricles
Marie Novakova et al.
GENERAL PHYSIOLOGY AND BIOPHYSICS (2010)
Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules
John Lekakis et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2010)
Sigma-1 Receptors Regulate Bcl-2 Expression by Reactive Oxygen Species-Dependent Transcriptional Regulation of Nuclear Factor κB
Johann Meunier et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Safety and Efficacy of Sertraline for Depression in Patients With Heart Failure
Christopher M. O'Connor et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)
σ1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding
Felix J. Kim et al.
MOLECULAR PHARMACOLOGY (2010)
Detergent-Resistant Microdomains Determine the Localization of σ-1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction
Teruo Hayashi et al.
MOLECULAR PHARMACOLOGY (2010)
THE SIGMA-1 RECEPTOR IS ENRICHED IN POSTSYNAPTIC SITES OF C-TERMINALS IN MOUSE MOTONEURONS. AN ANATOMICAL AND BEHAVIORAL STUDY
T. A. Mavlyutov et al.
NEUROSCIENCE (2010)
Direct involvement of σ-1 receptors in the dopamine D1 receptor-mediated effects of cocaine
Gemma Navarro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The sigma-1 receptor chaperone as an inter-organelle signaling modulator
Tsung-Ping Su et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2010)
Integrins and Extracellular Matrix in Mechanotransduction
Martin Alexander Schwartz
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Voltage-gated sodium channel modulation by σ-receptors in cardiac myocytes and heterologous systems
Molly Johannessen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)
Sigma-1 receptor knockout mice display a depressive-like phenotype
Valentina Sabino et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
The sigma1 receptor interacts with N-alkyl amines and endogenous sphingolipids
Subramaniam Ramachandran et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology
Fenghua Zeng et al.
EXPERIMENTAL CELL RESEARCH (2009)
Stimulation of Sigma-1 receptor signaling by dehydroepiandrosterone ameliorates pressure overload-induced hypertrophy and dysfunctions in ovariectomized rats
Md. Shenuarin Bhuiyan et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2009)
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice
Haiyun Ling et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
MAM: more than just a housekeeper
Teruo Hayashi et al.
TRENDS IN CELL BIOLOGY (2009)
Safety and efficacy of sertraline for depression in patients with CHF (SADHART-CHF): A randomized, double-blind, placebo-controlled trial of sertraline for major depression with congestive heart failure
Wei Jiang et al.
AMERICAN HEART JOURNAL (2008)
Epidermal Growth Factor Receptor Signaling in the Kidney Key Roles in Physiology and Disease
Wynand B. W. H. Melenhorst et al.
HYPERTENSION (2008)
Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the σ-1 receptor
Arindam Pal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
σ-1 Receptor Modulation of Acid-Sensing Ion Channel a (ASIC1a) and ASIC1a-Induced Ca2+ Influx in Rat Cortical Neurons
Yelenis Herrera et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
sigma-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, Bax levels, and caspase-3 activation
Kissaou T. Tchedre et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines
Christopher P. Palmer et al.
CANCER RESEARCH (2007)
IRE1 signaling affects cell fate during the unfolded protein response
Jonathan H. Lin et al.
SCIENCE (2007)
Sigma-1 receptor chaperones at the ER-Mitochondrion interface regulate Ca2+ signaling and cell survival
Teruo Hayashi et al.
CELL (2007)
Voltage-gated ion channels, new targets in anti-cancer research
Le Guennec Jean-Yves et al.
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY (2007)
Rubiscolin-6, a δ opioid peptide derived from spinach Rubisco, has anxiolytic effect via activating σ1, and dopamine D1 receptors
Hajime Hirata et al.
PEPTIDES (2007)
Signal integration in the endoplasmic reticulum unfolded protein response
David Ron et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2
Sufang Yang et al.
ANESTHESIA AND ANALGESIA (2007)
HIF-1α contributes to tumour-selective killing by the sigma receptor antagonist rimcazole
M. Achison et al.
ONCOGENE (2007)
The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus
Marzia Martina et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
The anti-amnesic and neuroprotective effects of donepezil against amyloid β25-35 peptide-induced toxicity in mice involve an interaction with the σ1 receptor
J. Meunier et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Expression, subcellular localization, and regulation of sigma receptor in retinal Muller cells
Guoliang Jiang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
The effect of chronic co-administration of fluvoxamine and haloperidol compared to clozapine on the GABA system in the rat frontal cortex
Yael Chertkow et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2006)
hERG potassium channels and cardiac arrhythmia
MC Sanguinetti et al.
NATURE (2006)
Sertraline versus fluvoxamine in the treatment of elderly patients with major depression - A double-blind, randomized trial
D Rossini et al.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2005)
Involvement of sigma (σ) receptors in the acute actions of methamphetamine:: Receptor binding and behavioral studies
EC Nguyen et al.
NEUROPHARMACOLOGY (2005)
σ receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons
HL Zhang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Relationship between release of platelet/endothelial biomarkers and plasma levels of sertraline and N-desmethylsertraline in acute coronary syndrome patients receiving SSRI treatment for depression
VL Serebruany et al.
AMERICAN JOURNAL OF PSYCHIATRY (2005)
Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a
O Yermolaieva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
ER chaperone functions during normal and stress conditions
YJ Ma et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2004)
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction - Possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis
K Okada et al.
CIRCULATION (2004)
σ-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells:: Potential relation to lipid raft reconstitution
M Takebayashi et al.
SYNAPSE (2004)
Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo
BA Spruce et al.
CANCER RESEARCH (2004)
Understanding the molecular mechanism of sigma-1 receptors: Towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction
TP Su et al.
CURRENT MEDICINAL CHEMISTRY (2003)
Generation and phenotypic analysis of sigma receptor type I (σ1) knockout mice
F Langa et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events - The Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) platelet substudy
VL Serebruany et al.
CIRCULATION (2003)
σ-1 receptors (σ1 binding sites) form raft-like microdomains and target lipid droplets on the endoplasmic reticulum:: Roles in endoplasmic reticulum lipid compartmentalization and export
T Hayashi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Intracellular dynamics of σ-1 receptors (σ1 binding sites) in NG108-15 cells
T Hayashi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Influence of depression and effect of treatment with sertraline on quality of life after hospitalization for acute coronary syndrome
JR Swenson et al.
AMERICAN JOURNAL OF CARDIOLOGY (2003)
The sigma receptor as a ligand-regulated auxiliary potassium channel subunit
E Aydar et al.
NEURON (2002)
Sigma receptors: from discovery to highlights of their implications in the cardiovascular system
L Monassier et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2002)
Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor
P Seth et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2001)