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Interaction of the motor protein SecA and the bacterial protein translocation channel SecYEG in the absence of ATP
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Coassembly of SecYEG and SecA Fully Restores the Properties of the Native Translocon
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Protein translocation by the SecA ATPase occurs by a power-stroke mechanism
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Direct visualization of the E. coli Sec translocase engaging precursor proteins in lipid bilayers
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Protein Translocation Activity in Surface-Supported Lipid Bilayers
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Penetration into membrane of amino-terminal region of SecA when associated with SecYEG in active complexes
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The Hessian Blob Algorithm: Precise Particle Detection in Atomic Force Microscopy Imagery
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Dynamic action of the Sec machinery during initiation, protein translocation and termination
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Single-molecule observation of nucleotide induced conformational changes in basal SecA-ATP hydrolysis
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Structure-based working model of SecDF, a proton-driven bacterial protein translocation factor
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SecA functions in vivo as a discrete anti-parallel dimer to promote protein transport
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The SecA protein deeply penetrates into the SecYEG channel during insertion, contacting most channel transmembrane helices and periplasmic regions
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The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins
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Preprotein mature domains contain translocase targeting signals that are essential for secretion
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Imaging modes of atomic force microscopy for application in molecular and cell biology
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Lipids Activate SecA for High Affinity Binding to the SecYEG Complex
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Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation
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Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC
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Dynamic Structure of the Translocon SecYEG in Membrane DIRECT SINGLE MOLECULE OBSERVATIONS
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Phospholipids Induce Conformational Changes of SecA to Form Membrane-Specific Domains: AFM Structures and Implication on Protein-Conducting Channels
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Stoichiometry of SecYEG in the active translocase of Escherichia coli varies with precursor species
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Structure and function of a membrane component SecDF that enhances protein export
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Protein translocation across the bacterial cytoplasmic membrane
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Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation
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Solid supported lipid bilayers: From biophysical studies to sensor design
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The surprising complexity of signal sequences
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Depletion of SecDF-YajC causes a decrease in the level of SecG: implication for their functional interaction
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Direct demonstration of ATP-dependent release of SecA from a translocating preprotein by surface plasmon resonance
J de Keyzer et al.
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Ring-like pore structures of SecA: Implication for bacterial protein-conducting channels
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Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA
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A functional update of the Escherichia coli K-12 genome
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