4.7 Article

Facile preparation of pH-sensitive biocompatible alginate beads havening layered double hydroxide supported metal-organic framework for controlled release from doxorubicin to breast cancer cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Polymer Science

Application of different mathematical models for further investigation of in vitro drug release mechanisms based on magnetic nano-composite

Samira Jafari et al.

Summary: This study investigated drug release mechanisms on novel pre-synthesized magnetic nano-composite-based polyurethane matrices for in vitro breast cancer therapy. The Higuchi kinetic model was found to be the best-suited to describe the drug release pattern, explaining the drug diffusion-controlled manner.

POLYMER BULLETIN (2022)

Review Chemistry, Applied

Sodium alginate based drug delivery in management of breast cancer

Mohammad Arshad Javed Shaikh et al.

Summary: Breast cancer is a common disease among women worldwide, and sodium alginate as a drug carrier shows potential for treating breast cancer.

CARBOHYDRATE POLYMERS (2022)

Article Biochemistry & Molecular Biology

Magnetic alginate/glycodendrimer beads for efficient removal of tetracycline and amoxicillin from aqueous solutions

Soheyla Karimi et al.

Summary: In this study, new alginate beads were prepared for the effective removal of tetracycline (TC) and amoxicillin (AMX) antibiotics from aqueous solutions. The synthesized beads showed excellent adsorption capacity and reusability, making them a promising low-cost and eco-friendly adsorbent for antibiotic contaminants removal from aquatic environments.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Chemistry, Physical

Layered double hydroxide-galactose as an excellent nanocarrier for targeted delivery of curcumin to hepatocellular carcinoma cells

Sarina Mokhtari et al.

Summary: This study developed a drug delivery system based on LDH and Gal for targeted delivery of Cur, showing promising results including high cytotoxicity and apoptosis effects on HepG2 cells. The Gal-Cur/LDH nanoparticles demonstrated a specific targeting efficiency due to higher cellular uptake via ASGP-receptors. Our findings suggest the Gal-Cur/LDH nanoparticles as an excellent carrier system for targeted delivery of Cur to hepatocellular carcinoma cells.

APPLIED CLAY SCIENCE (2021)

Review Chemistry, Applied

A comprehensive review on alginate-based delivery systems for the delivery of chemotherapeutic agent: Doxorubicin

Jaya R. Lakkakula et al.

Summary: Combining alginate with other materials as a drug delivery system can effectively enhance the targeted therapeutic effects of doxorubicin on cancer, showing great potential for widespread applications.

CARBOHYDRATE POLYMERS (2021)

Article Chemistry, Physical

pH and ultrasound dual-responsive drug delivery system based on PEG-folate-functionalized Iron-based metal-organic framework for targeted doxorubicin delivery

Ahmed Ahmed et al.

Summary: This study synthesized dual-responsive iron-based MOFs and successfully loaded the anticancer drug DOX into them, demonstrating good colloidal stability with PEG-FA functionalized MOFs. The research confirmed the sensitivity of the nanovehicles to low-frequency ultrasound and showed their release efficiency under different pH values.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)

Article Chemistry, Physical

Synthesis of folic acid-conjugated glycodendrimer with magnetic β-cyclodextrin core as a pH-responsive system for tumor-targeted co-delivery of doxorubicin and curcumin

Soheyla Karimi et al.

Summary: This study successfully developed a novel magnetic carrier for targeted delivery of anticancer drugs, utilizing magnetic nanocomposites with antioxidant properties. The synthesized carrier showed controlled release of anticancer drugs, excellent cytotoxicity, and promising antioxidant activity, making it a potential co-drug delivery system for cancer therapy.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)

Review Biochemistry & Molecular Biology

Alginate-based hydrogels for cancer therapy and research

Belen Reig-Vano et al.

Summary: Alginate is considered a potential vehicle for therapeutic factors encapsulation, with its unique ability to form hydrogels that resemble natural soft tissues. This innovative approach can address systemic toxicity and tumor resistance caused by traditional therapies, while increasing the bioavailability of encapsulated compounds. Alginate-based systems show great promise in the field of cancer therapy and research, with applications in delivery systems, cell culture scaffolds, and tumor biomarkers immunosensing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Chemistry, Multidisciplinary

Advanced drug delivery applications of layered double hydroxide

V. K. Ameena Shirin et al.

Summary: Layered double hydroxides (LDHs) are nanomaterials with high surface-to-volume ratio, suitable for drug delivery applications. Interlayered drugs can be released in a sustained manner, reducing drug administration frequency.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Pharmacology & Pharmacy

Multi-Component Hydrogel Beads Incorporated with Reduced Graphene Oxide for pH-Responsive and Controlled Co-Delivery of Multiple Agents

Sreekanth Reddy Obireddy et al.

Summary: The study reports the generation of multi-component hydrogel beads incorporated with reduced graphene oxide, which are shown to be more effective in inhibiting the growth of MCF-7 cells. The drug release sustainability of the beads is affected by the pH of the release medium, increasing in neutral pH but decreasing in acidic environments.

PHARMACEUTICS (2021)

Article Chemistry, Multidisciplinary

Drug Release Kinetics of DOX-Loaded Graphene-Based Nanocarriers for Ovarian and Breast Cancer Therapeutics

Katherine Taylor et al.

Summary: This study identified seventeen publications on the release of doxorubicin from 2D graphene-based nanohybrids for breast and ovarian cancer treatment, analyzing pre-clinical experimental protocols and release kinetics. The majority of the data best fit the Weibull kinetic model, providing a predictable estimation of DOX release from graphene-based nanocarriers. This research demonstrates the potential conjugation of graphene and DOX in drug delivery applications.

APPLIED SCIENCES-BASEL (2021)

Review Biochemistry & Molecular Biology

Lignin, lipid, protein, hyaluronic acid, starch, cellulose, gum, pectin, alginate and chitosan-based nanomaterials for cancer nanotherapy: Challenges and opportunities

Carolina Carrillo Carrion et al.

Summary: Nanotechnology-driven drug delivery systems are rapidly evolving in cancer treatment, with green nanomedicines showing promise for improved outcomes. Natural biopolymers and nanomaterials play vital roles in cancer nanotherapy, imaging, and management.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Chemistry, Physical

Fe3O4@PEG-coated dendrimer modified graphene oxide nanocomposite as a pH-sensitive drug carrier for targeted delivery of doxorubicin

Soheyla Karimi et al.

Summary: The study successfully fabricated a triazine dendrimer-functionalized graphene oxide nanocarrier for drug delivery systems with potential applications in cancer treatment. The results showed that the nanocarrier exhibited pH-responsive drug release behavior, excellent biocompatibility, and higher apoptotic effects on breast cancer cells.

JOURNAL OF ALLOYS AND COMPOUNDS (2021)

Article Nanoscience & Nanotechnology

In Situ Biosynthesis of a Metal Nanoparticle Encapsulated in Alginate Gel for Imageable Drug-Delivery System

Moon Il Kim et al.

Summary: The development of drug-delivery systems for in vivo imaging has attracted significant interest. A novel strategy involving the encapsulation of metal nanoparticles within alginate gel was reported. This system can be conveniently and safely utilized for both in vitro and in vivo bioimaging purposes.

ACS APPLIED MATERIALS & INTERFACES (2021)

Article Biochemistry & Molecular Biology

Alginate-azo/chitosan nanocapsules in vitro drug delivery for hepatic carcinoma cells: UV-stimulated decomposition and drug release based on trans-to-cis isomerization

Qi Chen et al.

Summary: A nanocapsule (AL-azo/CH) was developed in this study using alginate-azo and chitosan, which had UV-responsive drug release capabilities. When irradiated with 365-nm light, the nanocapsules exhibited controlled drug release and internalization by HepG2 cells, showing potential for nano-therapeutics with external control in polysaccharide field.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Biochemistry & Molecular Biology

Facile preparation of layered double hydroxide (LDH)-alginate beads as sustainable system for the triggered release of diclofenac: Effect of pH and temperature on release rate

Gianluca Viscusi et al.

Summary: This paper explores the facile preparation of alginate beads encapsulating layered double hydroxide (LDH) intercalated with diclofenac sodium for drug delivery systems. The study evaluates the effect of LDH carrier, release kinetics of diclofenac at different pH and temperatures, and the fabrication of a sustainable composite characterized by a triggered drug release rate. Empirical relationships correlating the drug diffusion as a function of temperature and pH were also extrapolated.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Biochemistry & Molecular Biology

Cu (II)-porphyrin metal-organic framework/graphene oxide: synthesis, characterization, and application as a pH-responsive drug carrier for breast cancer treatment

Zahra Gharehdaghi et al.

Summary: A new multifunctional nanocomposite CuG, consisting of Cu-TCPP MOF supported on GO nanosheets, was successfully fabricated for efficient drug loading and smart pH-responsive release in chemotherapy. In vitro experiments showed minimal cytotoxicity on normal cells and significant cancer cell-killing ability, indicating the potential for further biomedical investigations.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2021)

Article Multidisciplinary Sciences

Synthesis of a novel ternary ZIF-8/GO/MgFe2O4 nanocomposite and its application in drug delivery

Saleheh Sanaei-Rad et al.

Summary: This research successfully synthesized a nanocomposite of ZIF-8/GO/MgFe2O4 with high loading efficiency of tetracycline antibiotic drug, which showed good release profile and antibacterial activity on both gram-positive and gram-negative bacteria. The structure of synthesized materials was confirmed using various spectroscopic methods.

SCIENTIFIC REPORTS (2021)

Article Chemistry, Multidisciplinary

A photoluminescent folic acid-derived carbon dot functionalized magnetic dendrimer as a pH-responsive carrier for targeted doxorubicin delivery

Soheyla Karimi et al.

Summary: A novel targeted drug delivery system was successfully synthesized in this study, showing excellent biocompatibility and stability, suitable for delivering doxorubicin against lung cancer cells. The system exhibited pH-dependent drug release in vitro and can serve as an efficient vehicle for drug delivery.

NEW JOURNAL OF CHEMISTRY (2021)

Article Materials Science, Multidisciplinary

Chlorogenic acid intercalated Gadolinium-Zinc/Aluminium layered double hydroxide and gold nanohybrid for MR imaging and drug delivery

Muhammad Sani Usman et al.

MATERIALS CHEMISTRY AND PHYSICS (2020)

Article Biochemistry & Molecular Biology

Carboxymethylcellulose/layered double hydroxides bio-nanocomposite hydrogel: A controlled amoxicillin nanocarrier for colonic bacterial infections treatment

Saman Behzadi Nia et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

Simple preparation of maltose-functionalized dendrimer/graphene quantum dots as a pH-sensitive biocompatible carrier for targeted delivery of doxorubicin

Soheyla Karimi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

A bio-inspired magnetic natural hydrogel containing gelatin and alginate as a drug delivery system for cancer chemotherapy

Rana Jahanban-Esfahlan et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Materials Science, Biomaterials

Ciprofloxacin-intercalated layered double hydroxide-in-hybrid films as composite dressings for controlled antimicrobial topical delivery

Yadira Salguero et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Article Materials Science, Biomaterials

A biocompatible nanoplatform formed by MgAl-layered double hydroxide modified Mn3O4/N-graphene quantum dot conjugated-polyaniline for pH-triggered release of doxorubicin

Mina Ahmadi-Kashani et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Article Mechanics

MODELS FOR DRUG RELEASE OF GENTAMICIN IN A POLYLACTIC ACID MATRIX

Anna S. Morozova et al.

MATHEMATICS AND MECHANICS OF COMPLEX SYSTEMS (2020)

Article Biotechnology & Applied Microbiology

Synthesis and application of magnetic@layered double hydroxide as an anti-inflammatory drugs nanocarrier

Vahid Yousefi et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

Article Chemistry, Multidisciplinary

One-step dry synthesis of an iron based nano-biocomposite for controlled release of drugs

Sophia Varghese et al.

RSC ADVANCES (2020)

Article Biochemistry & Molecular Biology

Fabrication and characterization of pH-sensitive bio-nanocomposite beads havening folic acid intercalated LDH and chitosan: Drug release and mechanism evaluation

Shadpour Mallakpour et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Materials Science, Biomaterials

Antiproliferative effects of new magnetic pH-responsive drug delivery system composed of Fe3O4, CaAl layered double hydroxide and levodopa on melanoma cancer cells

Nahid Shahabadi et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Article Engineering, Chemical

Synthesis of Cu-Al LDH nanofluid and its application in spray cooling heat transfer of a hot steel plate

Samarshi Chakraborty et al.

POWDER TECHNOLOGY (2018)

Article Pharmacology & Pharmacy

Doxorubicin loaded large-pore mesoporous hydroxyapatite coated superparamagnetic Fe3O4 nanoparticles for cancer treatment

Negar Abbasi Aval et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)