相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Chromosome-level assembly of the Neolamarckia cadamba genome provides insights into the evolution of cadambine biosynthesis
Xiaolan Zhao et al.
PLANT JOURNAL (2022)
Comparative transcriptome analysis revealed the molecular mechanism of the effect of light intensity on the accumulation of rhynchophylline and isorhynchophylline in Uncaria rhynchophylla
Xiao-Hong Wang et al.
PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS (2022)
Engineering Catharanthus roseus monoterpenoid indole alkaloid pathway in yeast
Vyoma Mistry et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2022)
Transcriptome revealing the dual regulatory mechanism of ethylene on the rhynchophylline and isorhynchophylline in Uncaria rhynchophylla
Xue Li et al.
JOURNAL OF PLANT RESEARCH (2022)
Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry
Nan Qin et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Chemical Diversity and Bioactivities of Monoterpene Indole Alkaloids (MIAs) from Six Apocynaceae Genera
Afrah E. Mohammed et al.
MOLECULES (2021)
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT1A receptor: Insights from transcriptomics
Yan-Ling Qiao et al.
PHYTOMEDICINE (2021)
Tissue-specific transcriptome and metabolome analyses reveal a gene module regulating the terpenoid biosynthesis in Curcuma wenyujin
Chengxi Jiang et al.
INDUSTRIAL CROPS AND PRODUCTS (2021)
Chromosome-level genome assembly of Ophiorrhiza pumila reveals the evolution of camptothecin biosynthesis
Amit Rai et al.
NATURE COMMUNICATIONS (2021)
The transcription factor OpWRKY2 positively regulates the biosynthesis of the anticancer drug camptothecin in Ophiorrhiza pumila
Xiaolong Hao et al.
HORTICULTURE RESEARCH (2021)
Alkaloids extracted from Uncaria rhynchophylla demonstrate neuroprotective effects in MPTP-induced experimental parkinsonism by regulating the PI3K/Akt/mTOR signaling pathway
Meizhu Zheng et al.
JOURNAL OF ETHNOPHARMACOLOGY (2021)
The Main Alkaloids in Uncaria rhynchophylla and Their Anti-Alzheimer's Disease Mechanism Determined by a Network Pharmacology Approach
Peng Zeng et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Unraveling the roles of plant specialized metabolites: using synthetic biology to design molecular biosensors
Constantine Garagounis et al.
NEW PHYTOLOGIST (2021)
Therapeutic potential of indole alkaloids in respiratory diseases: A comprehensive review
Saikat Mitra et al.
PHYTOMEDICINE (2021)
A chromosome-level Camptotheca acuminata genome assembly provides insights into the evolutionary origin of camptothecin biosynthesis
Minghui Kang et al.
NATURE COMMUNICATIONS (2021)
Properties, Pharmacology, and Pharmacokinetics of Active Indole and Oxindole Alkaloids in Uncaria Hook
Hirotaka Kushida et al.
FRONTIERS IN PHARMACOLOGY (2021)
Effect of Uncaria rhynchophylla against Thioacetamide-Induced Acute Liver Injury in Rat
Mi-Rae Shin et al.
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2021)
Uncaria rhynchophylla and its Major Constituents on Central Nervous System: A Review on Their Pharmacological Actions
Wen Yang et al.
CURRENT VASCULAR PHARMACOLOGY (2020)
Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions
Elisabeth Eger et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Heterologous overexpression of Nothapodytes foetida strictosidine synthase enhances levels of anti-cancer compound camptothecin in Ophiorrhiza rugosa
Sudhir Singh et al.
PLANT CELL TISSUE AND ORGAN CULTURE (2020)
Identifying Missing Biosynthesis Enzymes of Plant Natural Products
Thomas Duge de Bernonville et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2020)
Nimble Cloning: A Simple, Versatile, and Efficient System for Standardized Molecular Cloning
Pu Yan et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)
Indole Alkaloids with Potential Anticancer Activity
Dan Xu et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2020)
TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data
Chengjie Chen et al.
MOLECULAR PLANT (2020)
Discovery and engineering of colchicine alkaloid biosynthesis
Ryan S. Nett et al.
NATURE (2020)
Beyond the semi-synthetic artemisinin: metabolic engineering of plant-derived anti-cancer drugs
Ines Carqueijeiro et al.
CURRENT OPINION IN BIOTECHNOLOGY (2020)
Computational Study of Pictet-Spenglerase Strictosidine Synthase: Reaction Mechanism and Origins of Enantioselectivity of Natural and Non-Natural Substrates
Xiang Sheng et al.
ACS CATALYSIS (2020)
Completion of the canonical pathway for assembly of anticancer drugs vincristine/vinblastine in Catharanthus roseus
Yang Qu et al.
PLANT JOURNAL (2019)
Evaluation of the effects of Uncaria rhynchophylla alkaloid extract on LPS-induced preeclampsia symptoms and inflammation in a pregnant rat model
Liang-Zhi Wu et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2019)
A specialized metabolic network selectively modulates Arabidopsis root microbiota
Ancheng C. Huang et al.
SCIENCE (2019)
Uncarialins A-I, Monoterpenoid Indole Alkaloids from Uncaria rhynchophylla as Natural Agonists of the 5-HT1A Receptor
Jia-Hao Liang et al.
JOURNAL OF NATURAL PRODUCTS (2019)
Cross-family transcription factor interaction between MYC2 and GBFs modulates terpenoid indole alkaloid biosynthesis
Xueyi Sui et al.
JOURNAL OF EXPERIMENTAL BOTANY (2018)
MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms
Sudhir Kumar et al.
MOLECULAR BIOLOGY AND EVOLUTION (2018)
Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle
Lorenzo Caputi et al.
SCIENCE (2018)
Assessing Flux Distribution Associated with Metabolic Specialization of Glandular Trichomes
Jordan J. Zager et al.
TRENDS IN PLANT SCIENCE (2018)
A differentially regulated AP2/ERF transcription factor gene cluster acts downstream of a MAP kinase cascade to modulate terpenoid indole alkaloid biosynthesis in Catharanthus roseus
Priyanka Paul et al.
NEW PHYTOLOGIST (2017)
Chemical and biological comparison of different sections of Uncaria rhynchophylla (Gou-Teng)
Jian-Gang Zhang et al.
EUROPEAN JOURNAL OF MASS SPECTROMETRY (2017)
A Global Coexpression Network Approach for Connecting Genes to Specialized Metabolic Pathways in Plants
Jennifer H. Wisecaver et al.
PLANT CELL (2017)
Integrated omics analysis of specialized metabolism in medicinal plants
Amit Rai et al.
PLANT JOURNAL (2017)
A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate
Evangelos C. Tatsis et al.
NATURE COMMUNICATIONS (2017)
Hirsutine, an Indole Alkaloid of Uncaria rhynchophylla, Inhibits Late Step in Dengue Virus Lifecycle
Takayuki Hishiki et al.
FRONTIERS IN MICROBIOLOGY (2017)
Discovery and metabolic engineering of iridoid/secoiridoid and monoterpenoid indole alkaloid biosynthesis
Antje M. K. Thamm et al.
PHYTOCHEMISTRY REVIEWS (2016)
The basic helix-loop-helix transcription factor BIS2 is essential for monoterpenoid indole alkaloid production in the medicinal plant Catharanthus roseus
Alex Van Moerkercke et al.
PLANT JOURNAL (2016)
An integrated strategy for the systematic characterization and discovery of new indole alkaloids from Uncaria rhynchophylla by UHPLC/DAD/LTQ-Orbitrap-MS
Huiqin Pan et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2015)
Medicinal uses, phytochemistry and pharmacology of the genus Uncaria
Qian Zhang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2015)
MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis
Hiroshi Tsugawa et al.
NATURE METHODS (2015)
De novo production of the plant-derived alkaloid strictosidine in yeast
Stephanie Brown et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus
Alex Van Moerkercke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone
Warren Lau et al.
SCIENCE (2015)
Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila
Lijie Cui et al.
SCIENTIFIC REPORTS (2015)
De novo transcriptome sequencing and digital gene expression analysis predict biosynthetic pathway of rhynchophylline and isorhynchophylline from Uncaria rhynchophylla, a non-model plant with potent anti-alzheimer's properties
Qianqian Guo et al.
BMC GENOMICS (2014)
Genomic Signatures of Specialized Metabolism in Plants
Lee Chae et al.
SCIENCE (2014)
The seco-iridoid pathway from Catharanthus roseus
Karel Miettinen et al.
NATURE COMMUNICATIONS (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
A review on indole alkaloids isolated from Uncaria rhynchophylla and their pharmacological studies
Andre Ndagijimana et al.
FITOTERAPIA (2013)
MYC2: The Master in Action
Kemal Kazan et al.
MOLECULAR PLANT (2013)
Suppression of camptothecin biosynthetic genes results in metabolic modification of secondary products in hairy roots of Ophiorrhiza pumila
Takashi Asano et al.
PHYTOCHEMISTRY (2013)
Co-expression and co-responses: within and beyond transcription
Takayuki Tohge et al.
FRONTIERS IN PLANT SCIENCE (2012)
Convergent Evolution in Plant Specialized Metabolism
Eran Pichersky et al.
ANNUAL REVIEW OF PLANT BIOLOGY, VOL 62 (2011)
The basic helix-loop-helix transcription factor CrMYC2 controls the jasmonate-responsive expression of the ORCA genes that regulate alkaloid biosynthesis in Catharanthus roseus
Hongtao Zhang et al.
PLANT JOURNAL (2011)
The Transcription Factor CrWRKY1 Positively Regulates the Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus
Nitima Suttipanta et al.
PLANT PHYSIOLOGY (2011)
Formation of plant metabolic gene clusters within dynamic chromosomal regions
Ben Field et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Phylogenetic and transcriptional analysis of a strictosidine synthase-like gene family in Arabidopsis thaliana reveals involvement in plant defence responses
M. M. Sohani et al.
PLANT BIOLOGY (2009)
3D-Structure and function of strictosidine synthase - the key enzyme of monoterpenoid indole alkaloid biosynthesis
Joachim Stoeckigt et al.
PLANT PHYSIOLOGY AND BIOCHEMISTRY (2008)
Downregulation of terpenoid indole alkaloid biosynthetic pathway by low temperature and cloning of a AP2 type C-repeat binding factor (CBF) from Catharanthus roseus (L). G. Don
Ajaswrata Dutta et al.
PLANT CELL REPORTS (2007)
Molecular architecture of strictosidine glucosidase:: The gateway to the biosynthesis of the monoterpenoid indole alkaloid family
Leif Barleben et al.
PLANT CELL (2007)
Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's β-amyloid proteins
Hironori Fujiwara et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2006)
STEM: a tool for the analysis of short time series gene expression data
J Ernst et al.
BMC BIOINFORMATICS (2006)
The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed β-propeller fold in plant proteins
XY Ma et al.
PLANT CELL (2006)
Chemistry and biology of monoterpene indole alkaloid biosynthesis
Sarah E. O'Connor et al.
NATURAL PRODUCT REPORTS (2006)
Inhibitory effects of Choto-san (Diao-teng-san), and hooks and stems of Uncaria sinensis on free radical-induced lysis of rat red blood cells
N Sekiya et al.
PHYTOMEDICINE (2002)
ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism
L van der Fits et al.
SCIENCE (2000)
分享论文
