A new potential ONO Schiff-Base ligand and its Cu(II), Zn(II) and Cd(II) Complexes: Synthesis, structural Elucidation, theoretical and bioactivity studies

Article Biochemistry & Molecular Biology

A Treatise on Furan Cored Schiff Base Cu(II), Ni(II) and Co(III) Complexes Accentuating Their Biological Efficacy: Synthesis, Thermal and Spectroscopic Characterization, DNA Interactions, Antioxidant and Antibacterial Activity Studies

Kadtala Venkateswarlu et al.

Summary: Three metal complexes were synthesized and characterized, and their interactions with DNA, DNA cleavage ability, and antibacterial activity were investigated. Complex 3 exhibited the strongest activity among all the complexes.

CHEMISTRY & BIODIVERSITY (2022)

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Article Chemistry, Inorganic & Nuclear

Binuclear Zn(II) Schiff base complexes: Synthesis, spectral characterization, theoretical studies and antimicrobial investigations

Hadi Kargar et al.

Summary: Binuclear zinc(II) Schiff base complexes were synthesized and characterized through spectroscopic analysis, revealing their centrosymmetric nature and enhanced antimicrobial activity compared to the ligands. Additionally, theoretical calculations using density functional theory supported the experimental findings.

INORGANICA CHIMICA ACTA (2022)

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Article Chemistry, Physical

Synthesis, molecular docking, molecular dynamic, quantum calculation, and antibacterial activity of new Schiff base-metal complexes

Heba E. Hashem et al.

Summary: The study focused on the synthesis, characterization, in vitro evaluation, and molecular dynamics study of Co(II) and Cu(II) metal containing Schiff base-metal complexes. The metal complexes showed higher antibacterial activity than the metal free ligands, with the highest activity observed against P. vulgaris. Computational tools, such as Density Functional Theory (DFT), molecular docking, and molecular dynamics, were used to evaluate the theoretical and biological activity, with results showing the Cobalt complex {L1-Co (4)} exhibiting the highest biological activity.

JOURNAL OF MOLECULAR STRUCTURE (2022)

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Article Chemistry, Applied

DNA binding, cleavage, docking, biological and kinetic studies of Cr(III), Fe(III), Co(II) and Cu(II) complexes with ortho-vanillin Schiff base derivative

Kavitha Bengi et al.

Summary: A new metal complex ligand was synthesized and characterized, showing octahedral and square planar geometries for different complexes. The complexes demonstrated strong DNA binding affinity and potential antitumor activity, with IC50 values indicating inhibitory efficiency.

APPLIED ORGANOMETALLIC CHEMISTRY (2022)

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Article Chemistry, Physical

Synthesis, characterization, DNA interaction, BSA/HSA binding activities of VO(IV), Cu(II) and Zn(II) Schiff base complexes and its molecular docking with biomolecules

Shunmugasundaram Gurusamy et al.

Summary: In this study, Schiff base metal complexes of VO(IV), Cu(II), and Zn(II) were synthesized and characterized. The metal complexes exhibited good antibacterial activity against Staphylococcus aureus and strong antioxidant activity against DPPH radicals. Spectroscopic studies confirmed the binding of the metal complexes with DNA and protein molecules. Molecular docking studies provided insights into the interactions between the metal complexes and biomolecules.

JOURNAL OF MOLECULAR LIQUIDS (2022)

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Article Chemistry, Physical

Three organotin(IV) Schiff-base carboxylates: Synthesis, structural characterization and in vitro cytotoxicity against cis-platin-resistent cancer cells

Shuxian Yu et al.

Summary: Three new organotin(IV) complexes have been synthesized by reacting organotin(IV) chlorides with Schiff base carboxylic acid ligand. The complexes were characterized and evaluated for their structural features and cytotoxicities. The results showed that the di-n-butyltin(IV) and triphenyltin(IV) complexes exhibited higher cytotoxicities, possibly due to the generation of intracellular reactive oxygen species (ROS).

JOURNAL OF MOLECULAR STRUCTURE (2022)

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Article Chemistry, Applied

Tetracoordinated ONNO donor purine-based Schiff base and its metal complexes: Synthesis, characterization, DNA binding, theoretical studies, and bioactivities

Anmol Singh et al.

Summary: A novel Schiff base compound and its metal complexes were synthesized and characterized. The complexes exhibited better antioxidant, anti-inflammatory, and antibacterial activities compared to the free ligand. The compounds showed potential as therapeutic agents.

APPLIED ORGANOMETALLIC CHEMISTRY (2022)

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Article Chemistry, Inorganic & Nuclear

Comparative study of palladium(II) complexes bearing tridentate ONS and NNS Schiff base ligands: Synthesis, characterization, DFT calculation, DNA binding, bioactivities, catalytic activity, and molecular docking

Anmol Singh et al.

Summary: This study synthesized two palladium (II) Schiff base complexes and characterized their structures using various analytical techniques. The results showed that these complexes exhibited biological activities when reacted with specific acids, bases, or enzymes. Additionally, molecular docking experiments demonstrated the binding mechanisms of these complexes with DNA and certain enzymes.

POLYHEDRON (2022)

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Article Chemistry, Multidisciplinary

Template synthesis, DNA binding, antimicrobial activity, Hirshfeld surface analysis, and 1D helical supramolecular structure of a novel binuclear coppe(II) Schiff base complex

Hamid Goudarziafshar et al.

Summary: A new binuclear copper(I) Schiff base complex was synthesized using a template method, and its unique structural features and intermolecular interactions were revealed. The complex was found to bind with CT-DNA and exhibit significant antibacterial activities.

RSC ADVANCES (2022)

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Article Chemistry, Inorganic & Nuclear

Novel copper(II) and zinc(II) complexes of halogenated bidentate N,O-donor Schiff base ligands: Synthesis, characterization, crystal structures, DNA binding, molecular docking, DFT and TD-DFT computational studies

Hadi Kargar et al.

Summary: Eight novel complexes containing four bidentate N,O-donor halogenated bis-Schiff base ligands were synthesized and their structures were confirmed by various spectroscopic techniques. Both experimental and theoretical results demonstrated that the DNA-binding affinity of the complexes increases with decreasing electronegativity of the substituted halogen atom.

INORGANICA CHIMICA ACTA (2021)

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Article Materials Science, Multidisciplinary

Influence of Thermal Processing for 3D Printed Components

Dragos Alexandrescu et al.

Summary: Additive manufacturing process by fused deposition modeling plays an important role in the medical field due to its ability to create complex organic geometries and high customization. Thermal processing is used to alleviate anisotropy and improve mechanical behavior of 3D printed parts, although samples may become more brittle during the process.

MATERIALE PLASTICE (2021)

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Review Chemistry, Medicinal

Pt(II) and Au(III) complexes containing Schiff-base ligands: A promising source for antitumor treatment

Ying Sun et al.

Summary: The Pt(II) and Au(III) Schiff-base complexes as potential antitumor agents have shown remarkable biological activities and good stability. They act through different mechanisms, providing a feasible solution for improving the side effects of metal chemotherapy.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)

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Article Chemistry, Physical

Synthesis, characterization, catalytic, DNA binding and antibacterial activities of Co(II), Ni(II) and Cu(II) complexes with new Schiff base ligand

Ola A. El-Gammal et al.

Summary: The synthesis, characterization, and bioactivities of a new Schiff base ligand and its metal complexes, including coordination mode, DNA binding behavior, antimicrobial activity, antioxidant activity, and anticancer activity, were investigated in this study.

JOURNAL OF MOLECULAR LIQUIDS (2021)

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Article Chemistry, Multidisciplinary

Nickel(II), copper(II) and zinc(II) complexes containing symmetrical Tetradentate Schiff base ligand derived from 3,5-diiodosalicylaldehyde: Synthesis, characterization, crystal structure and antimicrobial activity

Hadi Kargar et al.

Summary: Novel transition metal complexes of nickel(II), copper(II) and zinc(II) with a symmetrical tetradentate Schiff base have been synthesized and characterized, showing significant antibacterial potential compared to the Schiff base ligand.

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Inorganic & Nuclear

Some new Cu(II) complexes containing O,N-donor Schiff base ligands derived from 4-aminoantipyrine: synthesis, characterization, crystal structure and substitution effect on antimicrobial activity

Hadi Kargar et al.

Summary: A series of new mononuclear Cu(II) complexes with bis-O,N-bidentate Schiff base ligands have been synthesized and characterized, with C4 showing a highly distorted square planar geometry. Antibacterial activity studies revealed a wide range of antimicrobial activity due to different electronic environments of the substituents on the phenolic moiety.

JOURNAL OF COORDINATION CHEMISTRY (2021)

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Article Chemistry, Physical

Structural characterization and biological activity of a new metal complexes based of Schiff base

Ola A. El-Gammal et al.

Summary: Metal complexes of Co(II), Ni(II) and Cu(II) with a new Schiff base have been synthesized and characterized. The study suggests potential therapeutic applications against cancer and COVID-19. Additionally, antioxidant and antibacterial activities of these complexes have been evaluated.

JOURNAL OF MOLECULAR LIQUIDS (2021)

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Article Chemistry, Physical

Synthesis, crystal structure, theoretical calculation, spectroscopic and antibacterial activity studies of copper(II) complexes bearing bidentate schiffbase ligands derived from 4-aminoantipyrine: Influence of substitutions on antibacterial activity

Hadi Kargar et al.

Summary: A series of novel Cu(II) complexes with four bis-N,O-bidentate Schiffbase ligands were synthesized and characterized. The crystal structures of some complexes were determined by single crystal X-ray analysis, confirming the coordination mode. Theoretical calculations and biological activity evaluation showed promising results for potential antimicrobial agents.

JOURNAL OF MOLECULAR STRUCTURE (2021)

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Article Chemistry, Physical

Synthesis, characterization and DNA interaction of a novel Pt(II) macroacyclic Schiff base complex containing the piperazine moiety and its cytotoxicity and molecular docking

Leila Nemati et al.

Summary: A new platinum Schiff base complex has been synthesized and studied for its interactions with DNA, showing significant interactions including partial intercalation mode with DNA and strong cytotoxic effects on human prostate carcinoma cells.

JOURNAL OF MOLECULAR LIQUIDS (2021)

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Article Chemistry, Physical

Studies on the effect of remote substituents on the DNA binding activity of novel chiral Schiff bases

Aditi Bora et al.

Summary: Three new chiral Schiff Bases (L-1, L-2, and L-3) were synthesized and characterized, with their crystal structures determined for L-1 and L-2. The study revealed the impact of remote substituents on both structure and biological activity of the Schiff bases, and investigated their interaction with calf-thymus DNA using various methods. The DNA binding affinity was found to be highest for L-3 among the three Schiff Bases.

JOURNAL OF MOLECULAR STRUCTURE (2021)

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Article Biochemistry & Molecular Biology

Synthesis, characterization, and DNA binding study of ruthenium(II/III) complexes containing ONS donor Schiff base

Anmol Singh et al.

Summary: A chelating ligand with thioether and ONS donor, Schiff base HL, was synthesized alongside its corresponding metal complexes RuL1 and RuL2. The binding ability studies showed that the ligand HL and complex RuL1 interact with calf-thymus DNA through an intercalative binding mode, while the complex RuL2 did not show any interaction with DNA due to steric effects.

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2021)

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Article Chemistry, Physical

Synthesis, characterization, molecular docking and DNA cleavage study of transition metal complexes of o-vanillin and glycine derived Schiff base ligand

Anindita De et al.

JOURNAL OF MOLECULAR STRUCTURE (2020)

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Article Chemistry, Applied

Synthesis, structural characterization, and properties of triorganotin complexes of Schiff base derived from 3-aminobenzoic acid and salicylaldehyde or 2,4-pentanedione

Lexing Chen et al.

APPLIED ORGANOMETALLIC CHEMISTRY (2020)

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Article Chemistry, Multidisciplinary

Synthesis, structural characterization and biological activities of metal(II) complexes with Schiff bases derived from 5-bromosalicylaldehyde: Ru(II) complexes transfer hydrogenation

Kenan Buldurun et al.

JOURNAL OF SAUDI CHEMICAL SOCIETY (2019)

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Article Chemistry, Applied

Inner metal complexes of tetradentate Schiff base: Synthesis, characterization, biological activity and molecular docking studies

M. A. Diab et al.

APPLIED ORGANOMETALLIC CHEMISTRY (2019)

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Article Chemistry, Applied

Synthesis, characterization of Schiff base metal complexes and their biological investigation

A. Z. El-Sonbati et al.

APPLIED ORGANOMETALLIC CHEMISTRY (2019)

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Article Chemistry, Inorganic & Nuclear

Synthesis, structural characterization, antioxidant, antimicrobial, DNA incision evaluation and binding investigation studies on copper(II) and cobalt(II) complexes of benzothiazole cored Schiff bases

Sreenu Daravath et al.

JOURNAL OF COORDINATION CHEMISTRY (2019)

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Article Chemistry, Physical

Synthesis, characterization, anticancer properties and theoretical study of asymmetrical Cd(II)-N2-Schiff base complexes

Zahra Saedi et al.

JOURNAL OF MOLECULAR STRUCTURE (2019)

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Article Chemistry, Inorganic & Nuclear

Synthesis, DNA binding and antibacterial activity of metal(II) complexes of a benzimidazole Schiff base

Khalid Mahmood et al.

POLYHEDRON (2019)

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Article Chemistry, Physical

Studies on DNA binding properties of new Schiff base ligands using spectroscopic, electrochemical and computational methods: Influence of substitutions on DNA-binding

Arezoo Jamshidvand et al.

JOURNAL OF MOLECULAR LIQUIDS (2018)

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Article Chemistry, Physical

New transition metal complexes of 2,4-dihydroxybenzaldehyde benzoylhydrazone Schiff base (H2dhbh): Synthesis, spectroscopic characterization, DNA binding/cleavage and antioxidant activity

Seyada A. Aboafia et al.

JOURNAL OF MOLECULAR STRUCTURE (2018)

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Article Chemistry, Multidisciplinary

Synthesis, characterization, crystal structures and antibacterial activities of some Schiff bases with N2O2 donor sets

Amir Adabi Ardakani et al.

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2018)

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Article Chemistry, Physical

Distorted square-antiprism geometry of new zirconium (IV) Schiff base complexes: Synthesis, spectral characterization, crystal structure and investigation of biological properties

Atefeh Sahraei et al.

JOURNAL OF MOLECULAR STRUCTURE (2017)

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Article Chemistry, Physical

Synthesis, characterization, DFT calculations and biological studies of Mn(II), Fe(II), Co(II) and Cd(II) complexes based on a tetradentate ONNO donor Schiff base ligand

Laila H. Abdel-Rahman et al.

JOURNAL OF MOLECULAR STRUCTURE (2017)

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Article Chemistry, Inorganic & Nuclear

Synthesis, characterization, crystal structures and biological activities of eight-coordinate zirconium(IV) Schiff base complexes

Atefeh Sahraei et al.

TRANSITION METAL CHEMISTRY (2017)

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Article Biochemical Research Methods

Co-culture engineering for microbial biosynthesis of 3-amino-benzoic acid in Escherichia coli

Haoran Zhang et al.

BIOTECHNOLOGY JOURNAL (2016)

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Article Chemistry, Physical

Synthesis, characterization, crystal structure and HSA binding of two new N,O,O-donor Schiff-base ligands derived from dihydroxybenzaldehyde and tert-butylamine

Iman Khosravi et al.

JOURNAL OF MOLECULAR STRUCTURE (2016)

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Article Biochemical Research Methods

Co-culture engineering for microbial biosynthesis of 3-amino-benzoic acid in Escherichia coli

Haoran Zhang et al.

BIOTECHNOLOGY JOURNAL (2016)

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Article Chemistry, Inorganic & Nuclear

Synthesis, characterization and biological activity of two Schiff base ligands and their nickel(II), copper(II), zinc(II) and cadmium(II) complexes derived from S-4-picolyldithiocarbazate and X-ray crystal structure of cadmium(II) complex derived from pyridine-2-carboxaldehyde

Teng-Jin Khoo et al.

INORGANICA CHIMICA ACTA (2014)

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Article Biochemistry & Molecular Biology

Spectroscopic, electrochemical DNA binding and in vivo anti-inflammatory studies on newly synthesized Schiff bases of 4-aminophenazone

Nasima Arshad et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2014)

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Article Chemistry, Multidisciplinary

Synthesis and characterization of some new Cd(II) and Zn(II) macrocyclic Schiff base complexes derived from cyclocondensation of three new linear aromatic (N4) amines and 2,6-diacetylpyridine. Crystal structure and biological activity studies

Hassan Keypour et al.

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2014)

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Article Chemistry, Physical

Synthesis, spectroscopic characterization and antimicrobial studies of Co(II), Ni(II), Cu(II) and Zn(II) complexes with Schiff bases derived from 5-bromo-salicylaldehyde

Ahmed Nuri Kursunlu et al.

JOURNAL OF MOLECULAR STRUCTURE (2013)

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Article Spectroscopy

Synthesis, spectroscopic studies, molecular modeling and antimicrobial activity of binuclear Co(II) and Cu(II) complexes of 4,6-diacetylresorcinol

Magdy Shebl et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2013)

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Article Chemistry, Multidisciplinary

Design, synthesis, DNA binding ability, chemical nuclease activity and antimicrobial evaluation of Cu(II), Co(II), Ni(II) and Zn(II) metal complexes containing tridentate Schiff base

N. Raman et al.

JOURNAL OF SAUDI CHEMICAL SOCIETY (2013)

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Article Chemistry, Multidisciplinary

Synthesis, spectroscopic characterization and thermal studies of some rare earth metal complexes of unsymmetrical tetradentate Schiff base ligand

V. A. Shelke et al.

ARABIAN JOURNAL OF CHEMISTRY (2012)

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Article Spectroscopy

Spectroscopic characterization and biological activity of Zn(II), Cd(II), Sn(II) and Pb(II) complexes with Schiff base derived from pyrrole-2-carboxaldehyde and 2-amino phenol

Bibhesh K. Singh et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2010)

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Article Chemistry, Inorganic & Nuclear

Multispectroscopic DNA interaction studies of a water-soluble nickel(II) complex containing different dinitrogen aromatic ligands

Nahid Shahabadi et al.

TRANSITION METAL CHEMISTRY (2010)

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Article Chemistry, Multidisciplinary

A short history of SHELX

George M. Sheldrick

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES (2008)

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A new potential ONO Schiff-Base ligand and its Cu(II), Zn(II) and Cd(II) Complexes: Synthesis, structural Elucidation, theoretical and bioactivity studies

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