期刊
INFLAMMATORY BOWEL DISEASES
卷 29, 期 1, 页码 167-171出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/ibd/izac244
关键词
Crohn's disease; inflammatory bowel syndrome; mucin glycans; human stools; diagnosis
This study used mass spectrometry to analyze the fecal mucins of Crohn's disease patients and found a significant decrease in sialylated glycans compared to the control group. This may propose a new noninvasive tool for screening intestinal diseases.
Lay Summary For the first time, fecal mucins of Crohn's disease patients were analyzed by mass spectrometry. Compared with control subjects, Crohn's disease patients showed a significant decrease in sialylated glycans that we propose as new noninvasive tool for screening of intestinal diseases.
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