期刊
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
卷 62, 期 2, 页码 971-981出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.iecr.2c03446
关键词
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In this study, a syndiotactic polypropylene (sPP)/ isotactic polypropylene (iPP) composite tube with reinforced hoop strength and considerable biocompatibility was demonstrated. An iPP network was constructed in situ by rotation extrusion technology, which increased the orientation degree in the hoop direction. The modulus of the iPP fiber-reinforced tubes reached 4.28 MPa/rad, about three times higher than that of the sPP tube. The biocompatibility of the as-prepared tube was evaluated and confirmed to have no impact on cell shape or proliferation, overcoming the current lack of composite materials for medical interventional tubes and expanding the application of sPP matrix.
Medical tubes are important medical devices for interventional therapy. However, current tubes suffer from poor biocompatibility due to the heterogeneity of composites. In this study, we demonstrated a syndiotactic polypropylene (sPP)/ isotactic polypropylene (iPP) composite tube with reinforced hoop strength and considerable biocompatibility. Taking advantage of the same backbone structure of PP, an iPP network was constructed in situ by rotation extrusion technology, which not only promoted interfacial crystallization but also increased the orientation degree in the hoop direction. As a result, the modulus of the iPP fiber-reinforced tubes reached 4.28 MPa/rad, which is about three times than that of the sPP tube. The biocompatibility of the as-prepared tube was evaluated in vitro and in vivo, and sPP/ iPP had no impact on the cell shape or proliferation. This work overcomes the current bottleneck of a lack of composite materials for medical interventional tubes and simultaneously broadens the application of the sPP matrix.
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