1,2-Alkylarylation of Styrenes with α-Carbonyl Alkyl Bromides and Indoles Using Visible-Light Catalysis

A new intermolecular 1,2-alkylarylation of styrenes with alpha-carbonyl alkyl bromides and indoles using fac-[Ir(ppy)(3)] as the photoredox catalyst has been developed. The method allows the simultaneous formation of two new carbon-carbon bonds through three component reaction, and represents a new single-electron transfer (SET) strategy for the 1,2-alkylarylation of the styrenes with broad substrate scope and excellent functional group tolerance.