期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 81, 期 2, 页码 715-722出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b02410
关键词
-
资金
- Dalian Institute of Chemical Physics, Chinese Academy of Sciences
- NSFC [21472186, 21272231]
Formal regiodivergent C-H alkynylation of 2-pyridones bearing different N-substituents has been realized under Au(I) and Rh(III) catalysis using a hypervalent iodine alkyne reagent. When catalyzed by Au(I), the alkynylation occurred at the most electron-rich 5-position via an electrophilic alkynylation pathway. The selectivity was switched to the 6-position under assistance of an N-chelation group when a Rh(III) catalyst was employed. A rhodacylic complex has been isolated as a key intermediate.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据