期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 81, 期 24, 页码 12514-12519出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.6b02404
关键词
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资金
- Russian Scientific Fund [14-50-00069]
- Russian Science Foundation [14-50-00069] Funding Source: Russian Science Foundation
N-Arylation of 2-imidazolines with arylboronic acids promoted by copper(II) acetate in DMSO provides an attractive alternative to the earlier reported transition metal-catalyzed approaches employing (hetero)aryl halides as it taps into the vast reagent space of commercially available boronic acids and proceeds at ambient temperature. Many of the resulting compounds are distinctly lead-like, thus positioning the method developed well within the toolbox of lead-oriented synthesis.
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