期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 81, 期 18, 页码 8436-8443出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.6b01594
关键词
-
资金
- National NaturalScience Foundation of China [21202049]
- Recruitment Program of Global Experts (1000 Talents Plan)
- Natural Science Foundation of Fujian Province [2016J01064]
- Fujian Hundred Talents Plan
- Program of Innovative Research Team of Huaqiao University [Z14X0047]
Fe-catalyzed aerobic oxidative esterifications of arylacetonitriles with alcohols, tri alkoxsilanes, silicate esters, or borate esters have been developed. The acyl groups which were in situ generated via chemoselective C(CO)-CN bond cleavage were directly used as electrophiles, leading to corresponding aryl esters in good to excellent yields under molecular oxygen when attacked by alcohols or alcohol surrogates. Dioxygen serves as both oxidant and reactant in this protocol. The reaction has a very broad substrate scope. Cheap starting materials as well as environmentally benign and inexpensive iron catalyst and ideal oxidant O-2 feature this transformation and make it a practical and sustainable protocol to afford esters.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据