☆ 4.8 Article

Photoinduced, metal- and photosensitizer-free decarboxylative C-H (amino)alkylation of heteroarenes in a sustainable solvent

GREEN CHEMISTRY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Multidisciplinary

Visible-light-induced direct perfluoroalkylation/heteroarylation of [1.1.1]propellane to diverse bicyclo[1.1.1]pentanes (BCPs) under metal and photocatalyst-free conditions

Jiashun Zhu et al.

Summary: A green and novel multi-component reaction for direct perfluoroalkylation/heteroarylation of [1.1.1]propellane with heteroarenes and perfluoroalkyl iodines is described. This transformation is facilitated by visible light in the absence of any transition-metal catalysts and photocatalysts. Various heteroarenes and perfluoroalkyl iodines are well compatible, providing the corresponding products in moderate-to-good yields. The control experiments demonstrate that a radical-relay mechanism is responsible for the cascade reaction. Such a methodology offers an efficient and practical access to diverse 1-perfluoroalkyl-3-heteroaryl bicyclo[1.1.1]pentanes (BCPs) with the potential for various applications in organic synthesis.

GREEN CHEMISTRY (2023)

添加到收藏夹

Article Chemistry, Organic

Copper-catalysed α-functionalization of ketones with nucleophiles: universal and efficient access to nafimidone derivatives

Jiabin Shen et al.

Summary: In this study, we report the discovery of a convenient and efficient method to construct various C-X bonds using a copper catalytic system. This strategy offers mild reaction conditions and easy formation of different C-X bonds (C-O, C-Cl, C-Br, C-I, C-F and C-S). This methodology provides a universal and practical approach for synthesizing potentially bioactive nafimidone derivatives, thereby expanding the compound library for medicinal screening purposes.

ORGANIC CHEMISTRY FRONTIERS (2023)

添加到收藏夹

Review Chemistry, Multidisciplinary

Photoredox-Catalyzed C-H Functionalization Reactions

Natalie Holmberg-Douglas et al.

Summary: The fields of C-H functionalization and photoredox catalysis have gained significant interest and utility in various scientific disciplines. This review focuses on the use of photoredox catalysis in C-H functionalization reactions, highlighting both inorganic/organometallic and organic-based photoredox catalytic systems. The subdivision by reaction class (sp(2) or sp(3) C-H functionalization) provides perspective and tactical strategies for synthetic applications.

CHEMICAL REVIEWS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Metal-free visible-light-initiated direct C3 alkylation of quinoxalin-2(1H)-ones and coumarins with unactivated alkyl iodides

Jun Sun et al.

Summary: A new visible-light-promoted direct C3 alkylation method was reported for obtaining various valuable compounds at room temperature, showing convenient reaction conditions, broad substrate scope, and high functional-group tolerance without the need for metal or external photocatalysts.

GREEN CHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Application of Langlois' reagent (NaSO2CF3) in C-H functionalisation

Jiabin Shen et al.

Summary: This review provides an overview of the recent advances in the selective introduction of CF3 group into organic molecules using solid sodium trifluoromethanesulfinate. The eco-friendly and cost-effective nature of this method has made it a valuable tool for organic chemists in synthesizing various natural and bioactive compounds.

CHINESE CHEMICAL LETTERS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nontraditional Fragment Couplings of Alcohols and Carboxylic Acids: C(sp3)-C(sp3) Cross-Coupling via Radical Sorting

Holt A. Sakai et al.

Summary: Alcohols and carboxylic acids are important functional groups in organic chemistry that can undergo radical activation and transition metal catalysis under visible light photoredox catalysis. In this report, a dual combination of NHC-mediated deoxygenation and hypervalent iodine-mediated decarboxylation is used to achieve the C(sp3)-C(sp3) cross-coupling of alcohols and carboxylic acids. This method offers a mild and practical approach for the synthesis of alkyl-alkyl cross-coupled products.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enantioselective Giese Additions of Prochiral α-Amino Radicals

Antti S. K. Landenpera et al.

Summary: This study reveals a strategy to exert control over the newly formed stereocenter in radical reactions by incorporating a removable basic heteroarene, enabling the catalyst to exert control during the C-C bond forming step.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nickel Catalysis via SH2 Homolytic Substitution: The Double Decarboxylative Cross-Coupling of Aliphatic Acids

Artem Tsymbal et al.

Summary: In this study, a dual photo/nickel catalytic manifold was described, which includes a complementary sequence involving free radical generation, radical sorting via selective binding to a Ni(II) center, and bimolecular homolytic substitution (S(H)2) at a high-valent nickel-alkyl complex. This catalytic manifold enables the elusive cross-coupling of diverse aliphatic carboxylic acids to generate valuable C(sp(3))-C(sp(3))-products. The discovery provides important insights for addressing the long-standing challenge in fragment coupling chemistry.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Remote C(sp3)-H heteroarylation of N-fluorocarboxamides with quinoxalin-2(1H)-ones under visible-light-induced photocatalyst-free conditions

Liangming Xuan et al.

Summary: A visible-light-promoted remote benzylic/aliphatic C(sp(3))-H heteroarylation of N-fluorocarboxamides with quinoxalin-2(1H)-ones is reported for the first time. This transformation allows the synthesis of a wide range of biologically important 3-alkylated quinoxalin-2(1H)-ones under metal- and external photocatalyst-free conditions. The method shows good substrate scope, functional group tolerance, chemoselectivity, and regioselectivity.

GREEN CHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Photocatalytic C(sp3) radical generation via C-H, C-C, and C-X bond cleavage

Chia-Yu Huang et al.

Summary: This review presents recent advancements and representative examples in photocatalytic generation of C(sp(3)) radicals (R), categorized into C-H, C-C, and C-X bond cleavages based on key bond cleavages. A general mechanistic scenario and key steps in R formation are discussed in each section.

CHEMICAL SCIENCE (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis of β-hydroxysulfides via visible-light-driven and EDA complex-promoted hydroxysulfenylation of styrenes with heterocyclic thiols in EtOH under photocatalyst-free conditions

Ziren Chen et al.

Summary: A visible-light-promoted, electron donor-acceptor complex has been developed for the hydroxysulfenylation of styrenes, using eco-friendly air and green ethanol as the oxygen source and solvent respectively. This approach offers a novel strategy for the synthesis of beta-hydroxysulfides, with high yields and regioselectivity, without the need for external photocatalysts and transition metals.

GREEN CHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Visible-light induced dearomatization reactions

Yuan-Zheng Cheng et al.

Summary: This article presents an overview of visible-light-induced dearomatization reactions and their applications. These reactions provide a rapid and efficient way to synthesize complex molecules from simple aromatic compounds and have significant implications in the synthesis of natural products, medicinal chemistry, and materials science.

CHEMICAL SOCIETY REVIEWS (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Transition-Metal-Catalyzed Divergent C-H Functionalization of Five-Membered Heteroarenes

Siyeon Jeong et al.

Summary: The regiodivergent, non-directed C-H functionalization of five-membered heteroarenes with alkenes and alkynes has been successfully achieved, allowing systematic diversification of common structural cores. A carefully devised transition metal catalytic system and a judicious choice of metals, ligands, acid and base additives, and solvents are critical for achieving high selectivity in these reactions.

ACCOUNTS OF CHEMICAL RESEARCH (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Recent advances on non-precious metal-catalyzed C-H functionalization of N-heteroarenes

Atanu Bera et al.

Summary: This review article summarizes recent advances in the catalysis of C-H bond functionalization reactions of N-heteroarenes, focusing on sp(2) and sp(3) activation, categorized into various reactions like alkylation, alkenylation, borylation, cyanation, and annulation. It also discusses the practical utility of these catalytic protocols in late-stage drug development, as well as the scope for developing newer catalytic protocols and mechanistic studies of crucial processes.

CHEMICAL COMMUNICATIONS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

4CzIPN-tBu-Catalyzed Proton-Coupled Electron Transfer for Photosynthesis of Phosphorylated N-Heteroaromatics

Yan Liu et al.

Summary: 4,5,6-Tetrakis (3,6-di-tert-butyl-9H-carbazol-9-yl)-isophthalonitrile (4CzIPN-Bu-t) was developed as a photocatalyst for the phosphorus-radical-initiated cascade cyclization reaction of isocyanides. By using 4CzIPN-Bu-t as catalyst, a visible light-induced proton-coupled electron transfer strategy was developed for the generation of phosphorus-centered radicals, leading to the successful construction of phosphorylated phenanthridines, quinolines, and benzothiazoles.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Article Chemistry, Organic

Synthesis of (E)-Quinoxalinone Oximes through a Multicomponent Reaction under Mild Conditions

Jun Xu et al.

Summary: This research presents a novel method for synthesizing (E)-quinoxalinone oximes through a multicomponent reaction under mild conditions, yielding moderate-to-good results. The combination of Mannich-type reaction and radical coupling in this methodology offers a green and practical approach for the synthesis of potentially bioactive quinoxalinone-containing molecules.

ORGANIC LETTERS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Remarkable Activity of Potassium-Modified Carbon Nitride for Heterogeneous Photocatalytic Decarboxylative Alkyl/Acyl Radical Addition and Reductive Dimerization of para-Quinone Methides

Qian Yang et al.

Summary: By modifying the structure of carbon nitride, a heterogeneous photocatalytic system for both decarboxylative addition and reductive dimerization has been developed with remarkable catalytic activity. The system offers advantages such as lower catalyst loading, enhanced optical absorption, improved electron-hole separation, good recyclability, broad substrate scope, and easy scale-up in continuous flow for valued target synthesis.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2021)

添加到收藏夹

Article Chemistry, Organic

Photo-Induced Cross-Dehydrogenative Alkylation of Heteroarenes with Alkanes under Aerobic Conditions

Jun Xu et al.

Summary: A Minisci-type cross-dehydrogenative alkylation was reported using cerium chloride as a photocatalyst and air as an oxidant, showing excellent tolerance to functional groups and suitability for both heteroarene and alkane substrates, providing an alternative approach for late-stage functionalization of valuable substrates.

JOURNAL OF ORGANIC CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Thiol-Mediated α-Amino Radical Formation via Visible-Light-Activated Ion-Pair Charge-Transfer Complexes

Keishi Kohara et al.

Summary: Visible-light-activated electron donor-acceptor complexes provide unique reaction pathways for the synthesis of complex molecules under mild conditions. This study demonstrates a method for the reductive generation of α-amino radicals through the reaction of a visible-light-activated ion-pair charge-transfer complex, allowing for the development of a multicomponent coupling reaction to form substituted aminomethyl-cyclopentanes. The operationally straightforward transformation is versatile and enables the generation of cyclic amine-containing scaffolds from readily available feedstocks.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Silver-catalyzed decarboxylative C-H functionalization of cyclic aldimines with aliphatic carboxylic acids

Jingjing Wang et al.

Summary: The silver-catalyzed decarboxylative C-H alkylation of cyclic aldimines with abundant aliphatic carboxylic acids has been achieved under mild reaction conditions, producing moderate to good yields (32%-91%). The study also demonstrated the potential of the technology in gram-scale reactions and late-stage modification of drugs.

CHINESE CHEMICAL LETTERS (2021)

添加到收藏夹

Article Chemistry, Organic

Photoinduced Rapid Multicomponent Cascade Reaction of Aryldiazonium Salts with Unactivated Alkenes and TMSN3

Jiabin Shen et al.

Summary: This study demonstrates a photoinduced rapid multicomponent cascade reaction of aryldiazonium salts with unactivated alkenes and trimethylsilyl azide under oxidant-free conditions, providing a synthetic route for a wide range of unsymmetric azo compounds. The compounds are obtained in good to excellent yields under mild reaction conditions. The control experiment confirms the reaction mechanism follows a radical pathway.

ORGANIC LETTERS (2021)

添加到收藏夹

Article Chemistry, Physical

Metal-Free Heterogeneous Semiconductor for Visible-Light Photocatalytic Decarboxylation of Carboxylic Acids

Jiale Shi et al.

Summary: A protocol utilizing metal-free ceramic BCN for the photocatalytic decarboxylation of carboxylic acids has been developed, demonstrating efficient formation of carbon-centered radicals and carbon-carbon bonds, showing practicality and wide application prospects.

ACS CATALYSIS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Multicomponent Bifunctionalization of Methyl Ketones Enabled by Heterogeneous Catalysis and Solar Photocatalysis in Water

Jun Xu et al.

Summary: A novel and green multicomponent transformation for the alpha-bifunctionalization of methyl ketones has been successfully achieved by combining heterogeneous catalysis and solar photocatalysis, offering a sustainable and practical alternative for the modification of ketone derivatives in water and under an air atmosphere.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Rapid alkenylation of quinoxalin-2(1H)-ones enabled by the sequential Mannich-type reaction and solar photocatalysis

Lin Huang et al.

Summary: This study demonstrates a rapid alkenylation of quinoxalin-2(1H)-ones enabled by a combination of Mannich-type reaction and solar photocatalysis, providing a practical solution for the synthesis of potentially bioactive compounds containing a 3,4-dihydroquinoxalin-2(1H)-one structure.

CHINESE CHEMICAL LETTERS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Photoinduced Enhanced Decomposition of TBHP: A Convenient and Greener Pathway for Aqueous Domino Synthesis of Quinazolinones and Quinoxalines

Daisy Sarma et al.

Summary: The study presents a catalyst-free photoinduced process for the synthesis of N-heterocyclic moieties in aqueous medium using TBHP as an oxidizing agent, driven by the enhanced rate of decomposition under visible light irradiation. This environmentally friendly pathway eliminates the need for metal catalysts or photocatalysts, offering a green and sustainable approach in organic synthesis.

ACS OMEGA (2021)

添加到收藏夹

Article Chemistry, Organic

Visible-Light-Induced C-H Bond Aminoalkylation of Heterocycles by the Decarboxylation Coupling of Amino Acids

Yifan Li et al.

Summary: This study presents an efficient visible-light-induced decarboxylative coupling reaction of N-protecting alpha-amino acids with heterocycles for the generation of aminoalkylated heterocycles. A series of aminoalkylated heterocycles were obtained in moderate to good yields, utilizing an inexpensive organic photocatalyst under transition-metal-free conditions.

ORGANIC LETTERS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

A cross-dehydrogenative C(sp3)-H heteroarylation via photo-induced catalytic chlorine radical generation

Chia-Yu Huang et al.

Summary: Hydrogen atom abstraction from C(sp(3))-H bonds of naturally abundant alkanes for alkyl radical generation represents a promising yet underexplored strategy in the alkylation reaction designs. The authors demonstrate a photo-induced and chemical oxidant-free cross-dehydrogenative coupling between alkanes and heteroarenes using catalytic chloride and cobalt catalyst, achieving successful couplings with satisfactory yields. The dual catalytic platform features the in situ engendered chlorine radical for alkyl radical generation and exploits the cobaloxime catalyst for catalytic turnover enabling hydrogen evolution.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Direct para-C-H heteroarylation of anilines with quinoxalinones by metal-free cross-dehydrogenative coupling under an aerobic atmosphere

Jun Xu et al.

Summary: This study introduces a green and efficient metal-free cross-dehydrogenative coupling (CDC) method for the direct para-C-H heteroarylation of anilines with quinoxalinones. The reaction, performed in H2O/DMSO using air as the sole oxidant, shows good compatibility with various anilines and quinoxalinones, yielding moderate-to-good products. This methodology offers an environmentally friendly and efficient alternative for late-stage modification of nitrogen-containing compounds.

GREEN CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Selective oxidation of alkenes to carbonyls under mild conditions

Jun Xu et al.

Summary: This method describes a practical and sustainable way to synthesize aldehydes, ketones, and carboxylic acids from inexpensive olefinic feedstock. It utilizes commercially available and inexpensive tetrahydrofuran as the additive, molecular oxygen as the sole oxidant, and water as the solvent. A radical mechanism was found to be responsible for the oxidation reaction, enabling moderate-to-good yields of carbonyl compounds from a wide range of substituted alkenes.

GREEN CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Organic

Decarboxylative C-H alkylation of heteroarenes by copper catalysis

Xiaolong Zhu et al.

Summary: A versatile decarboxylative C-H alkylation method for heteroarenes using various alkyl carboxylic acids was developed with Cu(OTf)(2) and 4,4'-di-tert-butyl-2,2'-bipyridine as catalysts. The protocol extends the limited number of copper catalytic decarboxylation couplings, especially in the construction of C-sp(2)-C-sp(3) bonds.

ORGANIC CHEMISTRY FRONTIERS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds

Rolando Cannalire et al.

Summary: Late stage functionalization is a powerful tool for accelerating the identification of structure-activity relationships and optimizing ADME profiles of drugs. Visible-light photocatalysis offers a smooth and clean functionalization approach for drugs, with a critical assessment of current literature and highlighting expected future progress and potential applications in the field.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A combination of heterogeneous catalysis and photocatalysis for the olefination of quinoxalin-2(1H)-ones with ketones in water: a green and efficient route to (Z)-enaminones

Jun Xu et al.

Summary: This study describes a novel aqueous reaction for the olefination of quinoxalin-2(1H)-ones with ketones through a combinational strategy under mild conditions using a simple and cheap catalyst to synthesize (Z)-enaminones with moderate-to-good yields. This methodology successfully combines the heterogeneous Mannich reaction with photocatalysis, providing a green and practical approach for the synthesis of potentially bioactive (Z)-enaminones with a 3,4-dihydroquinoxalin-2(1H)-one skeleton.

GREEN CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Aryl acyl peroxides for visible-light induced decarboxylative arylation of quinoxalin-2(1H)-ones under additive-, metal catalyst-, and external photosensitizer-free and ambient conditions

Long-Yong Xie et al.

Summary: Aryl radicals were successfully generated from affordable aryl acyl peroxides in eco-friendly ethyl acetate under visible-light illumination without the need for any additive, metal catalyst, or external photosensitizer. The arylation of quinoxalin-2(1H)-ones was chemoselective and regioselective, allowing for good access to various 3-arylquinoxalin-2(1H)-ones.

GREEN CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Photo-triggered self-catalyzed fluoroalkylation/cyclization of unactivated alkenes: synthesis of quinazolinones containing the CF2R group

Jin Yang et al.

Summary: A novel photo-triggered self-catalyzed fluoroalkylation/cyclization of quinazolinones containing unactivated alkenes with various fluoroalkyl bromides has been developed. This transformation exhibits excellent substrate generality with respect to both the coupling partners. The method is the first example describing the C-sp(3)-Br bond homolysis of alkyl bromides via a substrate induced energy transfer process, and the mild conditions, tolerance to a wide range of functional groups, and operational simplicity make it practical for the synthesis of fluorine-containing ring-fused quinazolinones.

GREEN CHEMISTRY (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Electron-deficient boron-based catalysts for C-H bond functionalisation

Yuanhong Ma et al.

Summary: Boron-based catalytic systems have shown great potential in C-H functionalization, enriching the chemistry field and providing opportunities in synthetic chemistry, materials chemistry, and chemical biology.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Article Chemistry, Organic

Aroylation of Electron-Rich Pyrroles under Minisci Reaction Conditions

Joydev K. Laha et al.

ORGANIC LETTERS (2020)

添加到收藏夹

Article Chemistry, Physical

Bromide-Promoted Visible-Light-Induced Reductive Minisci Reaction with Aldehydes

Zhongzhen Wang et al.

ACS CATALYSIS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Electrophotocatalytic Decarboxylative C-H Functionalization of Heteroarenes

Xiao-Li Lai et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Chemistry, Organic

Metal-Free Radical-Mediated C(sp3)-H Heteroarylation of Alkanes

Xin Shao et al.

ORGANIC LETTERS (2020)

添加到收藏夹

Article Chemistry, Organic

Photocatalyst-, metal- and additive-free, direct C-H arylation of quinoxalin-2(1H)-ones with aryl acyl peroxides induced by visible light

Jun Xu et al.

ORGANIC CHEMISTRY FRONTIERS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Visible-light-mediated photoredox minisci C-H alkylation with alkyl boronic acids using molecular oxygen as an oxidant

Jianyang Dong et al.

CHEMICAL COMMUNICATIONS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Visible-light-mediated minisci C-H alkylation of heteroarenes with 4-alkyl-1,4-dihydropyridines using O2as an oxidant

Jianyang Dong et al.

GREEN CHEMISTRY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Visible light-induced direct α C-H functionalization of alcohols

Linbin Niu et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent Advances in the Catalytic Synthesis of 4-Quinolones

Chao Shen et al.

CHEM (2019)

添加到收藏夹

Article Chemistry, Organic

Visible Light-Promoted Aliphatic C-H Arylation Using Selectfluor as a Hydrogen Atom Transfer Reagent

Hong Zhao et al.

ORGANIC LETTERS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Visible-Light-Photosensitized Aryl and Alkyl Decarboxylative Functionalization Reactions

Tuhin Patra et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Chemistry, Applied

Metal-Free C3 Hydroxylation of Quinoxalin-2(1H)-ones in Water

Sha Peng et al.

ADVANCED SYNTHESIS & CATALYSIS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Visible-light-induced radical cyclization of N-allylbenzamides with CF3SO2Na to trifluoromethylated dihydroisoquinolinones in water at room temperature

Long Zou et al.

GREEN CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Visible-light-mediated Minisci C-H alkylation of heteroarenes with unactivated alkyl halides using O2 as an oxidant

Jianyang Dong et al.

CHEMICAL SCIENCE (2019)

添加到收藏夹

Review Chemistry, Organic

Photochemical C-H bond coupling for (hetero)aryl C(sp2)-C(sp3) bond construction

Yating Zhao et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Catalyst-free visible-light-initiated oxidative coupling of aryldiazo sulfones with thiols leading to unsymmetrical sulfoxides in air

Qishun Liu et al.

GREEN CHEMISTRY (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Visible-Light Photocatalysis: Does It Make a Difference in Organic Synthesis?

Leyre Marzo et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Decarboxylative reactions with and without light - a comparison

Johanna Schwarz et al.

GREEN CHEMISTRY (2018)

添加到收藏夹

Article Chemistry, Organic

Metal-Free-Visible Light C-H Alkylation of Heteroaromatics via Hypervalent Iodine-Promoted Decarboxylation

Julien Genovino et al.

ORGANIC LETTERS (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Catalytic enantioselective Minisci-type addition to heteroarenes

Rupert S. J. Proctor et al.

SCIENCE (2018)

添加到收藏夹

Article Chemistry, Organic

Selective remote C-H trifluoromethylation of aminoquinolines with CF3SO2Na under visible light irradiation in the absence of an external photocatalyst

Lulu Zhao et al.

ORGANIC CHEMISTRY FRONTIERS (2018)

添加到收藏夹

Review Chemistry, Organic

Recent developments in palladium-catalysed non-directed coupling of (hetero) arene C-H bonds with C-Z (Z = B, Si, Sn, S, N, C, H) bonds in bi(hetero)aryl synthesis

Pui Ying Choy et al.

ORGANIC CHEMISTRY FRONTIERS (2018)

添加到收藏夹

Article Chemistry, Organic

Metal-, Photocatalyst-, and Light-Free, Late-Stage C-H Alkylation of Heteroarenes and 1,4-Quinones Using Carboxylic Acids

Daniel R. Sutherland et al.

ORGANIC LETTERS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Visible-Light-Driven Iminyl Radical-Mediated C-C Single Bond Cleavage/Radical Addition Cascade of Oxime Esters

Xiao-Ye Yu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

添加到收藏夹

Article Chemistry, Physical

Photoredox/Bronsted Acid Co-Catalysis Enabling Decarboxylative Coupling of Amino Acid and Peptide Redox-Active Esters with N-Heteroarenes

Wan-Min Cheng et al.

ACS CATALYSIS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

The E factor 25 years on: the rise of green chemistry and sustainability

Roger A. Sheldon

GREEN CHEMISTRY (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Catalyst-Free and Redox-Neutral Innate Trifluoromethylation and Alkylation of Aromatics Enabled by Light

Peng Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

添加到收藏夹

Article Chemistry, Organic

Silver-Catalyzed Minisci Reactions Using Selectfluor as a Mild Oxidant

Jordan D. Galloway et al.

ORGANIC LETTERS (2017)

添加到收藏夹

Article Chemistry, Organic

Molecular Oxygen-Mediated Minisci-Type Radical Alkylation of Heteroarenes with Boronic Acids

Lizhi Zhang et al.

ORGANIC LETTERS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Direct Cα-heteroarylation of structurally diverse ethers via a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction

Shihui Liu et al.

CHEMICAL SCIENCE (2017)

添加到收藏夹

Article Chemistry, Physical

Visible Light-Mediated Direct Decarboxylative C-H Functionalization of Heteroarenes

R. Aleyda Garza-Sanchez et al.

ACS CATALYSIS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Simple and Clean Photo-induced Methylation of Heteroarenes with MeOH

Wenbo Liu et al.

CHEM (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Copper-Catalyzed Intermolecular Heck-Like Coupling of Cyclobutanone Oximes Initiated by Selective C-C Bond Cleavage

Binlin Zhao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Deaminative Strategy for the Visible-Light-Mediated Generation of Alkyl Radicals

Felix J. R. Klauck et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

C-H Functionalization of Azines

Kei Murakami et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Metal-Catalyzed Decarboxylative C-H Functionalization

Ye Wei et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent Advances in Radical C-H Activation/Radical Cross-Coupling

Hong Yi et al.

CHEMICAL REVIEWS (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Synthetic Utilization of α-Aminoalkyl Radicals and Related Species in Visible Light Photoredox Catalysis

Kazunari Nakajima et al.

ACCOUNTS OF CHEMICAL RESEARCH (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Organic Photoredox Catalysis

Nathan A. Romero et al.

CHEMICAL REVIEWS (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mechanism of the Stereoselective α-Alkylation of Aldehydes Driven by the Photochemical Activity of Enamines

Ana Bahamonde et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

A decarboxylative approach for regioselective hydroarylation of alkynes

Jing Zhang et al.

NATURE CHEMISTRY (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles

Megan H. Shaw et al.

SCIENCE (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Photoredox-mediated Minisci C-H alkylation of N-heteroarenes using boronic acids and hypervalent iodine

Guo-Xing Li et al.

CHEMICAL SCIENCE (2016)

添加到收藏夹

Article Chemistry, Applied

Metal-Free Oxidative Decarbonylative Coupling of Aliphatic Aldehydes with Azaarenes: Successful Minisci-Type Alkylation of Various Heterocycles

Ren-Jin Tang et al.

ADVANCED SYNTHESIS & CATALYSIS (2015)

添加到收藏夹

Review Chemistry, Multidisciplinary

Visible-Light-Induced Decarboxylative Functionalization of Carboxylic Acids and Their Derivatives

Jun Xuan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Alcohols as alkylating agents in heteroarene C-H functionalization

Jian Jin et al.

NATURE (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Silver-Catalyzed Arylation of (Hetero)arenes by Oxidative Decarboxylation of Aromatic Carboxylic Acids

Jian Kan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

添加到收藏夹

Article Chemistry, Medicinal

Rings in Drugs

Richard D. Taylor et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

添加到收藏夹

Article Chemistry, Medicinal

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among US FDA Approved Pharmaceuticals

Edon Vitaku et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Reduction of aryl halides by consecutive visible light-induced electron transfer processes

Indrajit Ghosh et al.

SCIENCE (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Direct Selective Oxidative Cross-Coupling of Simple Alkanes with Heteroarenes

Andrey P. Antonchick et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

添加到收藏夹

Article Chemistry, Organic

Synthesis and Minisci Reactions of Organotrifluoroborato Building Blocks

Marc Presset et al.

JOURNAL OF ORGANIC CHEMISTRY (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Photochemical activity of a key donor-acceptor complex can drive stereoselective catalytic α-alkylation of aldehydes

Elena Arceo et al.

NATURE CHEMISTRY (2013)

添加到收藏夹

Review Chemistry, Multidisciplinary

Visible-Light Photoredox Catalysis

Jun Xuan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

添加到收藏夹

Article Chemistry, Multidisciplinary

A New Reagent for Direct Difluoromethylation

Yuta Fujiwara et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

Decarboxylative coupling reactions: a modern strategy for C-C-bond formation

Nuria Rodriguez et al.

CHEMICAL SOCIETY REVIEWS (2011)

添加到收藏夹

Article Chemistry, Medicinal

The Medicinal Chemist's Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

Stephen D. Roughley et al.

JOURNAL OF MEDICINAL CHEMISTRY (2011)

添加到收藏夹

Article Chemistry, Medicinal

Structure-based design of novel potent nonpeptide thrombin inhibitors

NH Hauel et al.

JOURNAL OF MEDICINAL CHEMISTRY (2002)

添加到收藏夹

Article Chemistry, Multidisciplinary

Atom efficiency and catalysis in organic synthesis

RA Sheldon

PURE AND APPLIED CHEMISTRY (2000)

添加到收藏夹

Review Chemistry, Multidisciplinary

Nitrogen-containing ligands for asymmetric homogeneous and heterogeneous catalysis

F Fache et al.

CHEMICAL REVIEWS (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.