4.7 Article

Digestion, absorption, and transport properties of soy-fermented douchi hypoglycemic peptides VY and SFLLR under simulated gastrointestinal digestion and Caco-2 cell monolayers

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Food Science & Technology

Anti-diabetic effects of bioactive peptides: recent advances and clinical implications

Caleb Acquah et al.

Summary: Diabetes, especially type 2 diabetes, is a significant global health issue with increasing prevalence worldwide. Healthy diet, physical activity, maintaining a healthy weight, and medication are effective strategies to prevent and control diabetes. Majority of diabetic patients reside in countries with poor healthcare systems and financial infrastructure, making diabetes management cost-prohibitive. Bioactive peptides derived from food proteins have the potential to be used as nutraceuticals and drugs in combating metabolic disorders without known complications. Coupled with lifestyle modifications, bioactive peptides can influence enzyme activities to maintain normal blood sugar levels.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Review Food Science & Technology

Traditional fermented soybean products: processing, flavor formation, nutritional and biological activities

Libo Liu et al.

Summary: Traditional fermented soybean food has become an important part of people's diet due to its unique flavors and improved health benefits. This review comprehensively discusses the historical evolution, distribution, traditional fermentation processing, main sources and characteristics of fermented strains, flavor components, nutritional properties, and biological activities of four traditional fermented soybean foods including douchi, sufu, dajiang, and soy sauce. The review also identifies four major challenges faced by traditional fermented soybean foods, including high salt content, formation of biogenic amine, the presence of pathogenic microorganisms and mycotoxins, and quality inconsistency. It concludes that establishing scientific quality standards and innovative fermentation processes are potential solutions to address these issues and improve the safety of traditional fermented soybean products.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Article Biochemistry & Molecular Biology

Purification and characterization of hypoglycemic peptides from traditional Chinese soy-fermented douchi

Songfeng Yu et al.

Summary: This study identified two hypoglycemic peptides from douchi and found that they can promote glucose uptake by activating the AMPK and MAPK signaling pathways.

FOOD & FUNCTION (2022)

Review Food Science & Technology

Application of static in vitro digestion models for assessing the bioaccessibility of hydrophobic bioactives: A review

Yunbing Tan et al.

Summary: In vitro digestion models are valuable tools for studying the bioavailability of hydrophobic bioactives. Food matrix effects play a significant role in influencing the bioaccessibility of these bioactives in emulsified foods. Optimization of food matrix composition and structure can enhance bioaccessibility and potentially lead to healthier food products.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2022)

Review Chemistry, Applied

A comprehensive review on the glucoregulatory properties of food-derived bioactive peptides

Forough Jahandideh et al.

Summary: Research indicates that bioactive peptides in dietary proteins have potential positive effects on treating diabetes, but there are challenges in incorporating them into functional foods and nutraceuticals.

FOOD CHEMISTRY-X (2022)

Review Endocrinology & Metabolism

Exocytosis Proteins: Typical and Atypical Mechanisms of Action in Skeletal Muscle

Jinhee Hwang et al.

Summary: The impaired GLUT4 translocation and defects in SNARE proteins and their regulators are closely related to the pathogenesis of diabetes. Novel functions of SNARE proteins in pathways not typically associated with SNAREs may provide new therapeutic targets for combating insulin resistance and diabetes.

FRONTIERS IN ENDOCRINOLOGY (2022)

Article Food Science & Technology

Novel antioxidant and ACE inhibitory peptide identified from Arthrospira platensis protein and stability against thermal/pH treatments and simulated gastrointestinal digestion

Kai Wang et al.

Summary: Novel antioxidant and ACE inhibitory peptides VTAGLVGGGAGK and PTGNPLSP were screened from Arthrospira platensis protein hydrolysates, exhibiting high stability under thermal processing and various pH conditions. PTGNPLSP showed higher stability during in vitro gastrointestinal digestion compared to VTAGLVGGGAGK.

FOOD RESEARCH INTERNATIONAL (2021)

Article Agriculture, Multidisciplinary

Peptide Analogues of VPP and IPP with Improved Glucose Uptake Activity in L6 Myotubes can be Released from Cereal Proteins

Ling Liu et al.

Summary: The study investigated the effect of peptide analogues of VPP and IPP on glucose uptake activity, finding that IQP, IPQ, VPE, and VEP showed significantly higher glucose uptake activity than their parent peptides. These peptides were shown to promote glucose uptake via the adenosine monophosphate-activated protein kinase pathway accompanied by glucose transporter type 4 (Glut4) translocation rather than the insulin signaling pathway.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Article Chemistry, Applied

Purification and identification of novel ACE inhibitory and ACE2 upregulating peptides from spent hen muscle proteins

Hongbing Fan et al.

Summary: The study investigated the use of spent hen as a starting material for preparing antihypertensive peptides with both ACE inhibitory (ACEi) and ACE2 upregulating (ACE2u) activities. Several potent ACEi and ACE2u peptides were identified, supporting the potential use of spent hens as functional food ingredients and nutraceuticals for hypertension treatment.

FOOD CHEMISTRY (2021)

Review Food Science & Technology

Recently isolated antidiabetic hydrolysates and peptides from multiple food sources: a review

Bababode Adesegun Kehinde et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2020)

Review Biochemistry & Molecular Biology

Molecular interactions, bioavailability, and cellular mechanisms of angiotensin-converting enzyme inhibitory peptides

Hongbing Fan et al.

JOURNAL OF FOOD BIOCHEMISTRY (2019)

Article Biochemical Research Methods

INFOGEST static in vitro simulation of gastrointestinal food digestion

Andre Brodkorb et al.

NATURE PROTOCOLS (2019)

Article Agriculture, Multidisciplinary

Transport, Bioavailability, Safety, and Calmodulin-Dependent-Phosphodiesterase-Inhibitory Properties of Flaxseed-Derived Bioactive Peptides

Ifeanyi D. Nwachukwu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)

Review Endocrinology & Metabolism

Patient and physician preferences for type 2 diabetes medications: a systematic review

Mahdi Toroski et al.

JOURNAL OF DIABETES AND METABOLIC DISORDERS (2019)

Article Agriculture, Multidisciplinary

Identification of New Anti-inflammatory Peptides from Zein Hydrolysate after Simulated Gastrointestinal Digestion and Transport in Caco-2 Cells

Qiufang Liang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

Article Agriculture, Multidisciplinary

Stability and Transport of Spent Hen-Derived ACE-Inhibitory Peptides IWHHT, IWH, and IW in Human Intestinal Caco-2 Cell Monolayers

Hongbing Fan et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

Article Agriculture, Multidisciplinary

Transepithelial Transport of YWDHNNPQIR and Its Metabolic Fate with Cytoprotection against Oxidative Stress in Human Intestinal Caco-2 Cells

Feiran Xu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

Article Agriculture, Multidisciplinary

Transport Study of Egg-Derived Antihypertensive Peptides (LKP and IQW) Using Caco-2 and HT29 Coculture Monolayers

Qingbiao Xu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

Article Agriculture, Multidisciplinary

Peptidomics of Peptic Digest of Selected Potato Tuber Proteins: Post-Translational Modifications and Limited Cleavage Specificity

Subin R. C. K. Rajendran et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2016)

Review Nutrition & Dietetics

Bioavailability of milk protein-derived bioactive peptides: a glycaemic management perspective

Katy Horner et al.

NUTRITION RESEARCH REVIEWS (2016)

Article Food Science & Technology

Transepithelial transport of dry-cured ham peptides with ACE inhibitory activity through a Caco-2 cell monolayer

Marta Gallego et al.

JOURNAL OF FUNCTIONAL FOODS (2016)

Article Agriculture, Multidisciplinary

Transport of Antihypertensive Peptide RVPSL, Ovotransferrin 328-332, in Human Intestinal Caco-2 Cell Monolayers

Long Ding et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2015)

Article Agriculture, Multidisciplinary

Transport of Egg White ACE-Inhibitory Peptide, Gln-Ile-Gly-Leu-Phe, in Human Intestinal Caco-2 Cell Monolayers with Cytoprotective Effect

Long Ding et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)

Review Nutrition & Dietetics

Are intact peptides absorbed from the healthy gut in the adult human?

Warren M. Miner-Williams et al.

NUTRITION RESEARCH REVIEWS (2014)

Article Agriculture, Multidisciplinary

Transport of IRW, an Ovotransferrin-Derived Antihypertensive Peptide, in Human Intestinal Epithelial Caco-2 Cells

Satyanarayana Bejjani et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

Review Pharmacology & Pharmacy

Oral delivery of peptides and proteins using lipid-based drug delivery systems

Ping Li et al.

EXPERT OPINION ON DRUG DELIVERY (2012)

Article Agriculture, Multidisciplinary

The Bioavailable Octapeptide Gly-Ala-Hyp-Gly-Leu-Hyp-Gly-Pro Stimulates Nitric Oxide Synthesis in Vascular Endothelial Cells

Kazuo Shimizu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)

Article Food Science & Technology

The (193-209) 17-residues peptide of bovine β-casein is transported through Caco-2 monolayer

Daniela Regazzo et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2010)

Article Biochemistry & Molecular Biology

Transepithelial Transport Characteristics of the Antihypertensive Peptide, Lys-Val-Leu-Pro-Val-Pro, in Human Intestinal Caco-2 Cell Monolayers

Haiyan Sun et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2009)

Review Biochemistry & Molecular Biology

Serine peptidases: Classification, structure and function

M. J. Page et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Article Food Science & Technology

Bioavailability of the antihypertensive peptide LHLPLP:: Transepithelial flux of HLPLP

Ana Quiros et al.

INTERNATIONAL DAIRY JOURNAL (2008)

Article Biochemistry & Molecular Biology

Transport of a tripeptide, Gly-Pro-Hyp, across the porcine intestinal brush-border membrane

Misako Aito-Inoue et al.

JOURNAL OF PEPTIDE SCIENCE (2007)

Review Cell Biology

The GLUT4 glucose transporter

Shaohui Huang et al.

CELL METABOLISM (2007)

Article Biochemistry & Molecular Biology

Transport of angiotensin peptides across the Caco-2 monolayer

HL Chua et al.

PEPTIDES (2004)

Article Biochemistry & Molecular Biology

Transepithelial transport of the bioactive tripeptide, Val-Pro-Pro, in human intestinal Caco-2 cell monolayers

M Satake et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2002)