相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Targeting CDK4 and CDK6 in cancer
Shom Goel et al.
NATURE REVIEWS CANCER (2022)
Noncanonical TGF-β signaling leads to FBXO3-mediated degradation of ΔNp63α promoting breast cancer metastasis and poor clinical prognosis
Mengmeng Niu et al.
PLOS BIOLOGY (2021)
E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma
Jing Xu et al.
CELL DEATH & DISEASE (2021)
Hif-1α/Hsf1/Hsp70 signaling pathway regulates redox homeostasis and apoptosis in large yellow croaker (Larimichthys crocea) under environmental hypoxia
Sheng-Yu Luo et al.
ZOOLOGICAL RESEARCH (2021)
Transcriptional suppression of AMPKα1 promotes breast cancer metastasis upon oncogene activation
Yong Yi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Emerging roles of HSF1 in cancer: Cellular and molecular episodes
Ge Wang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2020)
Prognostic and predictive significance of nuclear HIF1α expression in locally advanced HNSCC patients treated with chemoradiation with or without nimotuzumab
Usha Patel et al.
BRITISH JOURNAL OF CANCER (2020)
HNSCC: Tumour Antigens and Their Targeting by Immunotherapy
Adrian von Witzleben et al.
CELLS (2020)
Head and neck squamous cell carcinoma
Daniel E. Johnson et al.
NATURE REVIEWS DISEASE PRIMERS (2020)
Survival rates of head and neck cancers in Ghana: a retrospective study at the Komfo Anokye Teaching Hospital
Osei Owusu-Afriyie et al.
BMC RESEARCH NOTES (2020)
HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia
Federica Frezzato et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Clinical update on head and neck cancer: molecular biology and ongoing challenges
Elham Alsahafi et al.
CELL DEATH & DISEASE (2019)
Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase
Kuo-Hui Su et al.
MOLECULAR CELL (2019)
Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress
Yang Wang et al.
REDOX BIOLOGY (2019)
TIP60 up-regulates?Np63? to promote cellular proliferation
Andrew J. Stacy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study
Barbara Burtness et al.
LANCET (2019)
Delta Np63 alpha down-regulates c-Myc modulator MM1 via E3 ligase HERC3 in the regulation of cell senescence
Yonglong Chen et al.
CELL DEATH AND DIFFERENTIATION (2018)
Small Molecule Inhibitors of HSF1-Activated Pathways as Potential Next-Generation Anticancer Therapeutics
Chiranjeev Sharma et al.
MOLECULES (2018)
A double dealing tale of p63: an oncogene or a tumor suppressor
Yonglong Chen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
CDK4 in lung, and head and neck cancers in old age: evaluation as a biomarker
J. Banerjee et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2017)
Metformin Promotes AMP-activated Protein Kinase-independent Suppression of ΔNp63α Protein Expression and Inhibits Cancer Cell Viability
Yong Yi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
C-Myc regulates radiation-induced G2/M cell cycle arrest and cell death in human cervical cancer cells
Fengmei Cui et al.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2017)
Loss of AMPK activation promotes the invasion and metastasis of pancreatic cancer through an HSF1-dependent pathway
Ke Chen et al.
MOLECULAR ONCOLOGY (2017)
ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis
Linshan Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
The HSF1-PARP13-PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis
Mitsuaki Fujimoto et al.
NATURE COMMUNICATIONS (2017)
Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis
Antonio Cigliano et al.
ONCOTARGET (2017)
Tobacco-related carcinogenesis in head and neck cancer
Ashok R. Jethwa et al.
CANCER AND METASTASIS REVIEWS (2017)
Heat stress-induced phosphorylation of FoxO3a signalling in rat skeletal muscle
T. Yoshihara et al.
ACTA PHYSIOLOGICA (2016)
Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial
Tanguy Y. Seiwert et al.
LANCET ONCOLOGY (2016)
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
R. L. Ferris et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma
Bo Mi Ku et al.
ONCOTARGET (2016)
The Heat Shock Transcription Factor HSF1 Induces Ovarian Cancer Epithelial-Mesenchymal Transition in a 3D Spheroid Growth Model
Chase D. Powell et al.
PLOS ONE (2016)
Unexpected role of CDK4 in a G2/M checkpoint
Karen E. Sheppard et al.
CELL CYCLE (2015)
Comprehensive genomic characterization of head and neck squamous cell carcinomas
Michael S. Lawrence et al.
NATURE (2015)
ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis
J. Bergholz et al.
ONCOGENE (2014)
A gain-of-function mutant p53-HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress
D. Li et al.
CELL DEATH & DISEASE (2014)
Heat Shock Factor 1 (HSF1) Controls Chemoresistance and Autophagy through Transcriptional Regulation of Autophagy-related Protein 7 (ATG7)
Shruti Desai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive Biomarkers
Vivian W. Y. Lui et al.
CANCER DISCOVERY (2013)
HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers
Marc L. Mendillo et al.
CELL (2012)
Heat Shock Factor Hsf1 Cooperates with ErbB2 (Her2/Neu) Protein to Promote Mammary Tumorigenesis and Metastasis
Caixia Xi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Functional HSF1 requires aromatic-participant interactions in protecting mouse embryonic fibroblasts against apoptosis via G2 cell cycle arrest
Ziwei Chang et al.
MOLECULES AND CELLS (2012)
Role of p63 in Development, Tumorigenesis and Cancer Progression
Johann Bergholz et al.
CANCER MICROENVIRONMENT (2012)
ΔNp63 Versatilely Regulates a Broad NF-κB Gene Program and Promotes Squamous Epithelial Proliferation, Migration, and Inflammation
Xinping Yang et al.
CANCER RESEARCH (2011)
KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to the hsp70 Promoter
Young Ju Yoon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cytoplasmic p63 immunohistochemistry is a useful marker for muscle differentiation: an immunohistochemical and immunoelectron microscopic study
Sarah E. Martin et al.
MODERN PATHOLOGY (2011)
Loss of HSF1 Results in Defective Radiation-Induced G2 Arrest and DNA Repair
Qiang Li et al.
RADIATION RESEARCH (2011)
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
Nicolas Stransky et al.
SCIENCE (2011)
Transcriptional Repression of miR-34 Family Contributes to p63-Mediated Cell Cycle Progression in Epidermal Cells
Dario Antonini et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2010)
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth
Y. H. Zhao et al.
ONCOGENE (2009)
Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer:: Pooled analysis in the international head and neck cancer epidemiology consortium
Mia Hashibe et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Identification of new p63 targets in human keratinocytes
Barbara Testoni et al.
CELL CYCLE (2006)
p63 regulates an adhesion programme and cell survival in epithelial cells
Danielle K. Carroll et al.
NATURE CELL BIOLOGY (2006)
p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
JW Rocco et al.
CANCER CELL (2006)
c-Myc alters the DNA damage-induced G2/M arrest in human mammary epithelial cells
JH Sheen et al.
BRITISH JOURNAL OF CANCER (2003)
Identification of CDK4 as a target of c-MYC
H Hermeking et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)