4.6 Editorial Material

ERH: a plug-and-play protein important for gene silencing and cell cycle progression

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Molecular basis for the recognition of CIZ1 by ERH

Xiaoyang Wang et al.

Summary: Enhancer of rudimentary homologue (ERH) is a small protein involved in a wide range of cellular events. This study reveals the molecular basis for the recognition between ERH and CDKN1A-interacting zinc finger protein 1 (CIZ1). The structure of ERH bound to CIZ1 is solved, providing new insights into the ligand-binding mode for ERH and the conserved roles of ERH orthologs.

FEBS JOURNAL (2023)

Article Cell Biology

Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans

Cecilia Perez-Borrajero et al.

Summary: The study reveals the architecture of the PETISCO complex in C. elegans and its interaction with RNA, as well as the definition of different biological functions by its effector proteins. It is shown to form an octameric assembly with each subunit present in two copies, playing roles in germ cells and early embryos.

GENES & DEVELOPMENT (2021)

Article Cell Biology

Diverse heterochromatin-associated proteins repress distinct classes of genes and repetitive elements

Ryan L. McCarthy et al.

Summary: McCarthy, Kaeding et al. identified H3K9me3-heterochromatin proteins that repress heterochromatic genes, with ERH playing a key role in global H3K9me3 maintenance in human cells. They also revealed four groups of srHC proteins that repress common genes and repeat elements, expanding our understanding of H3K9me3-based gene repression in vertebrates.

NATURE CELL BIOLOGY (2021)

Article Multidisciplinary Sciences

Molecular basis for PICS-mediated piRNA biogenesis and cell division

Xiaoyang Wang et al.

Summary: By studying the interaction network and structural details of the PICS complex, researchers have uncovered its essential roles in piRNA biogenesis and cell division. Understanding the structure and function of the PICS complex provides insights into its functions in cellular biology processes.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Formation of S. pombe Erh1 homodimer mediates gametogenic gene silencing and meiosis progression

Ditipriya Hazra et al.

SCIENTIFIC REPORTS (2020)

Review Genetics & Heredity

ERH proteins: connecting RNA processing to tumorigenesis?

Marc Graille et al.

CURRENT GENETICS (2020)

Article Biochemistry & Molecular Biology

ERH facilitates microRNA maturation through the interaction with the N-terminus of DGCR8

S. Chul Kwon et al.

NUCLEIC ACIDS RESEARCH (2020)

Article Cell Biology

PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability

Ricardo J. Cordeiro Rodrigues et al.

GENES & DEVELOPMENT (2019)

Article Multidisciplinary Sciences

A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing

Guodong Xie et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing

Gina Kavanaugh et al.

MOLECULAR AND CELLULAR BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Structure of the conserved transcriptional repressor enhancer of rudimentary homolog

C Wan et al.

BIOCHEMISTRY (2005)