期刊
EXPERT REVIEW OF NEUROTHERAPEUTICS
卷 22, 期 11-12, 页码 1031-1041出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14737175.2022.2155515
关键词
Attention impairment; memory impairment; meta-analysis; transcranial magnetic stimulation (TMS)
资金
- Zhejiang Medical and Health Research Project
- [2021ZH048]
Transcranial magnetic stimulation can significantly improve cognitive impairment, including attention and memory, in stroke patients, without increasing side effects. Further multi-center, high-quality, large-sample randomized controlled trials are needed to verify this effect.
BackgroundPrevious studies indicated inconsistent results for the treatment effect of repetitive transcranial magnetic stimulation (rTMS) on attention and memory impairment following stroke.MethodsRandomized controlled trials (RCTs) on TMS for the treatment of stroke were retrieved from Online databases. Data were analyzed by RevMan 5.3 software.ResultsTen RCTs performed in China were included, with a total of 591 younger post-stroke patients ranging in age from their 40s to their 60s. The meta-analysis indicated that TMS could significantly improve the recovery of cognitive impairment following a stroke, according to the Montreal Cognitive Assessment (MoCA) score (8 studies, MD = 2.69, 95% CI: 1.44 to 3.95, P < 0.0001), the Rivermead Behavioral Memory Test (RBMT) score (7 studies, MD = 1.74, 95% CI:1.13 to 2.34, P < 0.00001), and the Modified Barthel Index (MBI) for Activities of Daily Living (3 studies, MD = 8.83, 95% CI:5.34 to 12.32, P < 0.00001). Sub-group analysis of MoCA and RBMT suggested that a low-frequency (1 Hz) stimulation exhibited similar effect with a higher-frequency (10 Hz) treatment.DiscussionTMS might effectively improve the attention and memory impairment of stroke patients without increasing side effects. But this effect needs to be verified by more multi-center, high-quality, large-sample, rigorously designed RCTs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据