☆ 4.6 Editorial Material

Transbronchial cryobiopsy in lung transplantation: risk, reward and relevance

EUROPEAN RESPIRATORY JOURNAL (2023)

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Article Respiratory System

Lung allograft transbronchial cryobiopsy for critical ventilated patients: a randomised trial

Karina Loor et al.

Summary: This study compared transbronchial lung biopsy with 1.9mm and 2.4mm cryoprobes for critically ill lung transplant recipients requiring mechanical ventilation. The results showed that the 2.4mm cryoprobe group had the best quality of lung samples, providing the most definitive diagnoses, especially for acute lung rejection and rejection severity. The samples collected with the 2.4mm cryoprobe were larger, had more adequate alveolar tissue, more vessels per procedure, and no significant crush artefacts. Moderate bleeding was observed in 23% of cases, but no severe bleeding occurred.

EUROPEAN RESPIRATORY JOURNAL (2023)

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Article Respiratory System

European Respiratory Society guidelines on transbronchial lung cryobiopsy in the diagnosis of interstitial lung diseases

Daniel A. Korevaar et al.

Summary: This guideline provides evidence-based clinical practice recommendations for the role of transbronchial lung cryobiopsy (TBLC) in obtaining tissue-based diagnosis in patients with undiagnosed interstitial lung diseases (ILD). TBLC provides important diagnostic information with lower diagnostic yield compared to surgical lung biopsy (SLB), at reduced serious adverse events and length of hospitalisation.

EUROPEAN RESPIRATORY JOURNAL (2022)

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Article Respiratory System

Diagnostic yield, safety, and impact of transbronchial lung biopsy in mechanically ventilated, critically ill patients: a retrospective study

Alessandro Ghiani et al.

Summary: Transbronchial lung biopsy is a valuable alternative to surgical lung biopsy in mechanically ventilated critically ill patients, with a high diagnostic yield. However, potential adverse events and limited impact on treatment decisions should be considered when choosing this procedure.

BMC PULMONARY MEDICINE (2021)

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Article Respiratory System

Implementation of transbronchial lung cryobiopsy in a tertiary referral center for interstitial lung diseases: a cohort study on diagnostic yield, complications, and learning curves

Jesper Romhild Davidsen et al.

Summary: This study reports the experience of outpatient TBLC implementation in a tertiary referral ILD center from the largest investigated TBLC cohort in Scandinavia. The diagnostic yield and prevalence of complications obtained by TBLC in unclassifiable ILD patients support outpatient TBLC as a valuable and safe alternative for diagnosing ILD in well-selected patients. The learning curves for TBLC were acceptable under experienced bronchoscopists.

BMC PULMONARY MEDICINE (2021)

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Article Critical Care Medicine

Interstitial Lung Disease 2021 2 Early diagnosis of fibrotic interstitial lung disease: challenges and opportunities

Paolo Spagnolo et al.

Summary: This article discusses the challenges faced by patients and physicians in making an early diagnosis of fibrotic ILD, as well as strategies to facilitate early identification of patients with the disease. Timely identification and accurate diagnosis of fibrotic ILD poses substantial clinical challenges, but could potentially improve outcomes through early initiation of appropriate management.

LANCET RESPIRATORY MEDICINE (2021)

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Review Respiratory System

Transbronchial Cryobiopsy in Interstitial Lung Diseases State-of-the-Art Review for the Interventional Pulmonologist

Sameer K. Avasarala et al.

Summary: Interstitial lung diseases are a diverse group of disorders that are difficult to diagnose precisely, requiring various information for correct diagnosis. Transbronchial cryobiopsy has become a popular method for obtaining tissue samples, with significant research supporting its feasibility and safety over the past decade.

JOURNAL OF BRONCHOLOGY & INTERVENTIONAL PULMONOLOGY (2021)

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Article Critical Care Medicine

Diagnostic accuracy of transbronchial lung cryobiopsy for interstitial lung disease diagnosis (COLDICE): a prospective, comparative study

Lauren K. Troy et al.

LANCET RESPIRATORY MEDICINE (2020)

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Article Respiratory System

Bleeding risk of transbronchial cryobiopsy compared to transbronchial forceps biopsy in interstitial lung disease - a prospective, randomized, multicentre cross-over trial

Juergen Hetzel et al.

RESPIRATORY RESEARCH (2019)

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Article Cell Biology

The role of transbronchial cryobiopsy in lung transplantation

M. Angeles Montero et al.

HISTOPATHOLOGY (2018)

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Article Respiratory System

Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure

Juergen Hetzel et al.

RESPIRATION (2018)

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Article Critical Care Medicine

Cryoprobe Transbronchial Lung Biopsy in Patients After Lung Transplantation A Pilot Safety Study

Lonny Yarmus et al.

CHEST (2013)

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Review Critical Care Medicine

The Role of Surveillance Bronchoscopy Post-Lung Transplantation

Allan R. Glanville

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2013)

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Article Respiratory System

British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE

I. A. Du Rand et al.

THORAX (2013)

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Article Cardiac & Cardiovascular Systems

Single-institution Study Evaluating the Utility of Surveillance Bronchoscopy After Lung Transplantation

Vincent G. Valentine et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2009)

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Article Cardiac & Cardiovascular Systems

Surveillance Bronchoscopy in Lung Transplant Recipients: Risk versus Benefit

Tanya J. McWilliams et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2008)

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Article Immunology

The significance of a single episode of minimal acute rejection after lung transplantation

RR Hachem et al.

TRANSPLANTATION (2005)

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Article Surgery

Minimal acute rejection after lung transplantation: A risk for bronchiolitis obliterans syndrome

AP Khalifah et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2005)

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Article Cardiac & Cardiovascular Systems

Diagnostic properties of transbronchial biopsy in lung transplant recipients who require mechanical ventilation

KEA Burns et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2003)

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