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Article
Cardiac & Cardiovascular Systems
Ravi B. B. Patel et al.
Summary: This study evaluated the prevalence of AF among patients hospitalized for HFpEF and found that the prevalence is increasing. AF was significantly associated with increased risks of mortality and readmission within 12 months, particularly in HFpEF. The use of pharmacological rhythm control was found to be low.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Review
Medicine, General & Internal
Alberto Maria Marra et al.
Summary: HFpEF is a major healthcare issue with a high degree of disease heterogeneity, making it difficult to demonstrate the impact of drugs on morbidity and mortality in clinical trials.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Hajime Fujimoto et al.
Summary: This study found that patients with heart failure and reduced left ventricular ejection fraction (LVEF) had a higher risk for a composite of all-cause death, heart failure hospitalization, and stroke or systemic embolism after atrial fibrillation (AF) ablation compared to patients with mid-range or preserved LVEF. Reduced LVEF was identified as the most significant independent risk factor for this outcome.
Editorial Material
Cardiac & Cardiovascular Systems
Giuseppe Boriani et al.
Summary: This article discusses a post-hoc analysis of the ATHENA trial on the use of dronedarone for treating atrial fibrillation with concomitant heart failure. The findings suggest that dronedarone may have potential benefits in the treatment of this condition.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Medicine, General & Internal
Jacopo Francesco Imberti et al.
Summary: Clinical practice in atrial fibrillation patient management is constantly evolving. Various new guidelines have been published in the past few years, and they differ in key elements such as thromboembolic risk assessment, oral anticoagulants prescription, bleeding risk evaluation, and integrated patient management. The importance of an integrated and multidisciplinary approach to patient care is emerging.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Medicine, General & Internal
Luigi Tavazzi et al.
Summary: The use of catheter ablation of atrial fibrillation in heart failure patients is increasing, with current research focused mainly on patients with reduced left ventricular ejection fraction, while there is a lack of studies on patients with preserved ejection fraction. The current guidelines on catheter ablation of atrial fibrillation in heart failure patients may be inconsistent due to the lack of robust evidence.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Giuseppe Boriani et al.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Gesa von Olshausen et al.
Summary: This study investigates the association between catheter ablation for atrial fibrillation (AF) and mortality as well as hospitalization for heart failure (HF) in patients with HF across the ejection fraction (EF) spectrum. The results show that catheter ablation is associated with a lower risk of the primary outcome (all-cause mortality/first HF hospitalization) in HF patients, and this association remains consistent across different EF subgroups.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Medicine, General & Internal
Giulio Francesco Romiti et al.
Summary: Adherence to the ABC pathway reduces the risk of major outcomes in clinically complex AF patients, including all-cause death and major adverse cardiovascular events. Ensuring adherence to the ABC pathway is essential to improve clinical outcomes among these patients.
Article
Cardiac & Cardiovascular Systems
Lars Eckardt et al.
Summary: A strategy of systemic, early rhythm control has been found to improve cardiovascular outcomes in atrial fibrillation patients. The presence of sinus rhythm at 12 months is identified as a key mediator of this effect.
EUROPEAN HEART JOURNAL
(2022)
Article
Medicine, General & Internal
Prado Salamanca-Bautista et al.
Summary: Cardiovascular causes were the most frequent in deaths among heart failure patients, regardless of age, sex, and LVEF. More than half of patients died due to worsening HF, with stroke being more common among elderly patients, women, and those with preserved LVEF. Non-CV causes, particularly infectious diseases, accounted for a significant proportion of deaths, especially in the elderly and those with preserved LVEF.
INTERNAL AND EMERGENCY MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Adrianne Casebeer et al.
Summary: This study characterized subgroups of patients with newly identified HFpEF using unsupervised machine learning, identifying three distinguishable patient clusters representing different phenotypes. The study also evaluated 1-year heart failure related hospitalization rates, suggesting that patient subtypes may respond differently to treatments or interventions.
JOURNAL OF CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Biykem Bozkurt et al.
Summary: This document proposes a universal definition of heart failure as a clinical syndrome and revised stages of HF, as well as a new classification based on left ventricular ejection fraction (LVEF) levels. The classification includes HFrEF, HFmrEF, HFpEF, and HFimpEF based on LVEF percentages.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
Article
Medicine, General & Internal
Giuseppe Boriani et al.
Summary: The study aimed to assess the prevalence of unknown atrial fibrillation (AF) among adults during single-time point rhythm screening. Results showed a higher prevalence of unknown AF in the age group of >= 65 years, while no positive cases were found in the group aged below 50 years. Risk stratification based on certain criteria had high sensitivity and negative predictive value for AF detection.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Giuseppe Boriani et al.
Summary: Atrial fibrillation presents in various patterns and is associated with an increased risk of stroke, which is related to the duration of AF episodes. Monitoring AF burden and understanding factors that condition AF susceptibility are important for managing the disease and predicting adverse outcomes.
CARDIOVASCULAR RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Alicia Uijl et al.
Summary: This study identified five distinct clusters of HFpEF patients with different clinical characteristics, heart failure drug therapy, and prognosis, confirming the heterogeneity of HFpEF and providing a basis for tailoring drug therapy to individualized in HFpEF patients. Patients in cluster 1 had the best prognosis, while patients in clusters 3 and 5 had the worst age- and sex-adjusted prognosis.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
Review
Medicine, General & Internal
Daria Sgreccia et al.
Summary: Analysis of 10 studies showed no significant differences in all-cause mortality, cardiovascular death, stroke, and stroke/TE risks between symptomatic and asymptomatic AF patients. Therefore, the symptomatic status of AF patients does not impact mortality and stroke/TE events, suggesting that management strategies should not be solely based on symptomatic clinical presentation.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Vincenzo Livio Malavasi et al.
Summary: The study found that for patients with non-permanent atrial fibrillation, age, left atrial enlargement, severity of AF symptoms, antiarrhythmic drugs, and valvular disease are all associated with AF progression. Adding left atrial dilation to clinical scores can improve the prediction accuracy of progression to permanent AF.
INTERNAL AND EMERGENCY MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Biykem Bozkurt et al.
Summary: This document proposes a universal definition, revised stages, and new classification of heart failure based on left ventricular ejection fraction. The classification includes HF with reduced, mildly reduced, preserved, and improved ejection fraction, each with specific LVEF thresholds.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
